I've been on T replacement for almost a year now.
I was on the TD gel for many months and I did not absorb it well and had a lot of E2 symptoms. I was up to 2.5 ml of 10% gel and my levels barely hit 600.
I switched to the injections...they gave me tachycardia and heart palpitations especially when exerting myself or in heat. Even walking up stairs shot my heart to 130...this was consistent for over a month, it was terrible. Even when I lowered the injection amount and my T was around 600 again this still happened.
Going back on the cream resolves these issues in just a couple of days...this doesn't seem to be a bad reaction to the shot because for example, I can do a shot and have these symptoms but in 3-4 days if I add in some cream my heart calms down in like 24 hours.
My doc thinks these syptoms are due to my really low SHBG in combination with low E2. But that's just a theory...this is repeatable with 2 different brands of injectable... The only thing that would change between gel and injectable would seem to be E2 and DHT levels.
Anyone heard of this before?








