Medrol Vs. Hydrocortisone
- 04-07-2009, 03:24 PM
Medrol Vs. Hydrocortisone
I'm having major problems metabolizing HC (Cortef) way too fast. I can take 10 mg of HC and feel really good for about 45 min. & then it wears off quickly. It's causing some major ups & downs and I need to figure out if I need to switch to a longer acting corticosteroid like Medrol.
I have read though about the potential long term use of Medrol & some of the nasty sides associated with it. I'm also not sure if I want to put myself at risk for life time dependency if it permanently shuts down cortisol production. I'm hoping one day I can recover fully and if I should either really up my dosage of HC (would probably need around 50 mg a day the way I'm metabolizing it to feel stable)
I'm also wondering if anyone has experience with a sustained release version of HC & if that's a viable option. So, my options are to up my HC to a much higher dosage or switch over to Medrol. I'm trying to figure out the best course of action and if the risk & potential sides are worth switching over to Medrol. Does anyone have an opinion on what would be safer? High dosage HC throughout day versus one single dosage of Medrol? What's the safer option? Any opinions on sustained release HC, does it work? For those taking Medrol that have taken HC in the past, do you feel good & are you experiencing any bad side effects?
- 04-09-2009, 12:36 PM
Sounds to be like you are WAY overusing corts. Why not get down to the bottom of the issue of the pain? I think you are digging a deeper hole.
- 04-09-2009, 03:26 PM
04-09-2009, 05:31 PM
Medrol has serious side effects when used long term. I wouldnt go that route.
04-10-2009, 01:46 AM
04-10-2009, 11:01 AM
why not dose differently?
2.5mg every few hours?
04-10-2009, 03:33 PM
Be careful going by symptoms only, have you done a 4x cortisol test to show that its actually dropping out? These are not drugs to play around with (as I pop my 2.5mg HC afternoon dose)
04-10-2009, 06:26 PM
I'm actually slowly weaning off the HC because it obviously isn't working for me. I'm taking DHEA along with some other adrenal supplements while I'm doing this. I probably need to go back to baseline and figure out where I need to go from there.
04-14-2009, 02:43 PM
DHEAs(500-640)mcg/dL------------------major player, 95% time overlooked
Jan's BloodTest April13/2007
MESO-Rx - View Single Post - alternatives to HC
Corticosteroids conversion calculator (hydrocortisone, dexamethasone, prednisone, methylprednisolone, betamethasone
04-14-2009, 05:06 PM
I'm currently taking about 200mg of DHEA. For whatever reason, my body really needs it and it makes me feel much better. I did a Rhein's and my DHEA was double the top of the range (this was before taking dhea or anything else).
I have no idea why my body needs such a high amount. My LH & FSH are rock bottom, even though Test has been decent. I have to wonder if allot of that DHEA is being converted to Test because I suspect a sluggish pituitary. This in turn has probably put stress on adrenals over time causing adrenal fatigue.
I've pretty much weaned off HC because it wasn't working that well because it wore off so quickly. I only stress dose when I really need it. I'm wondering if adrenals would recover if I went on TRT to put stress off adrenals, or if it's too late for my adrenals & I need to go on Medrol anyway. I'm going back to baseline until I can approach with extreme caution.
04-14-2009, 09:31 PM
take as much DHEA as need to get there.
Do not use more than 30mg Cortef (or equivalent dose of Medrol)
cortef 30 mg---->methylprednisolone (Medrol) 6 mg
hydrocortisone 1 -8 hours
methylprednisolone 18- 36 hours
If you have a decent TotalTestosterone but low LH, FSH
Check what is your actual BAT(BioAvailableTestosterone)
FreeTestosterone (using chart not a test)
if you need boost, you may need just HCG.
To heal adrenals you need good sleep, DHEAs and decent testosterone.
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