Undermethylation and OverMethylation?

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    Quote Originally Posted by thenxtgrt1 View Post
    I believe I'm about to re-start a Sam-e protocol and also add in a few more ingredients. I'm not well-versed in under/over methylation. When I took sam-e in the past, I did notice positive well-being from it. And it seemed to help slightly with moderate back pain at the time.

    What I'd like to know presently...how does methlyation relate to inflammation? I haven't seen any literature that speaks directly on this. But I assume there is a correlation. A benefit often mentioned of Sam-e is reduction in joint pain. If I'm an under-methylator and I improve this, would inflammation also be reduced?
    SAm-3 increases glucosamine which helps in joint pains.
    I have all my athletes take it because it helps replenish gluthione stores
    along with 600-1200 mgs NAC.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.

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    I really find this information to be really informative. I suffer from Hg toxicity as I had amalgams in my mouth. ALso Cu i really high. I am taking Mo(Molybdenum) and VitC for this. Definitely, I am undermethyled as I have food allergies and MCS(mild). My eyes get really red when I go to the mall or shops. I have couple of questions

    1. Whenever I eat fatty foods evenlittle bit extremeties of my hand and feet get numb which to me is very clear from "Low Bile flow". I am sensitive to soy it effects my thyroid right away, i feel it. Took Milk thistle in the past now my saliva gets really foamy whenever I take it.
    What should I do.

    2. Tried taking TMG 50mg but experienced lot of anger so stopped. Why??? and what should I do???

    3. DIM makes my eyes red and feeel lot of burning. Isn't suppose to be good for you than why am I reacting to it????

    4. Wake up every night 3-4 hrs and can't go back to sleep.

    Thanks for listening !!!!
    Regards
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    Quote Originally Posted by EasyEJL View Post
    I'm doing it largely for the joint support, my thumb arthritis is nearing the point of needing surgery
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    I was talking with Dr E. Magaziner after my distal biceps tendon surgery.
    This theraphy was not applicable to speed healing of my tendon,
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    I also have arthritis in my thumb, so I asked about it.
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    Matrix - do you agree SAMe should be taken on an empty stomach??
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    Matrix - Need your input


    I really find your post about methylation to be very informative. I suffer from Hg toxicity as I had amalgams in my mouth. ALso Cu i really high. I am taking Mo(Molybdenum) and VitC for this. Definitely, I am undermethyled as I have food allergies and MCS(mild). My eyes get really red when I go to the mall or shops. I have couple of questions

    1. Whenever I eat fatty foods evenlittle bit extremeties of my hand and feet get numb which to me is very clear from "Low Bile flow". I am sensitive to soy it effects my thyroid right away, i feel it. Took Milk thistle in the past now my saliva gets really foamy whenever I take it.
    What should I do.

    2. Tried taking TMG 50mg but experienced lot of anger so stopped. Why??? and what should I do???

    3. DIM makes my eyes red and feeel lot of burning. Isn't suppose to be good for you than why am I reacting to it????

    4. Wake up every night 3-4 hrs and can't go back to sleep.

    Thanks for listening !!!!
    Regards[/QUOTE]
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    Quote Originally Posted by coolhammer View Post
    I really find your post about methylation to be very informative. I suffer from Hg toxicity as I had amalgams in my mouth. ALso Cu i really high. I am taking Mo(Molybdenum) and VitC for this. Definitely, I am undermethyled as I have food allergies and MCS(mild). My eyes get really red when I go to the mall or shops. I have couple of questions

    1. Whenever I eat fatty foods evenlittle bit extremeties of my hand and feet get numb which to me is very clear from "Low Bile flow". I am sensitive to soy it effects my thyroid right away, i feel it. Took Milk thistle in the past now my saliva gets really foamy whenever I take it.
    What should I do.

    2. Tried taking TMG 50mg but experienced lot of anger so stopped. Why??? and what should I do???

    3. DIM makes my eyes red and feeel lot of burning. Isn't suppose to be good for you than why am I reacting to it????

    4. Wake up every night 3-4 hrs and can't go back to sleep.

    Thanks for listening !!!!
    Regards
    [/QUOTE]


    Dim can be over loading the liver and methylation cycle. If you are already low on methylation you are getting over flood of the bad estrogens that are being recirulated back in to blood stream and not being escorted out proprely so you are getting an estrogen over load from the metabolites lingering around. This is putting more stress on your liver. I would swith to i50 mgs od iodoral which converts the bad estrones into estriol which is the protective kind. This would reduce liver stress tremendously by reducing stress on methylation cyles

    When ever my e2 goes high my eyes will start burning at night time for no reason once e2 is in check that stops the next night. You can also look at the bowel as primary source of estrogen because dyboisis will increase cirulatng estrogens as well which have not been properly packaged for removal.

    Every 3-4 hours is a sign your liver is imbalanced or your cortisol/thyroid is out of wack. Simple cortisol saliva test would answer that. in order to interpret your thyroid function you need to have proper lab work done. Please start a new thread so it could be easier to follow.

    Moly, seleneium are essential for proper methylation as b-12, folonic acid, p5p,

    if you are serious about your health and want to get better PM
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by jmh80 View Post
    Matrix - do you agree SAMe should be taken on an empty stomach??
    Yes 20-30 minutes before meals best time are before breakfast and mid afternoon give good stablility.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by The Matrix View Post
    Yes 20-30 minutes before meals best time are before breakfast and mid afternoon give good stablility.
    Hey bro, have a question. When people come out to see you, do you muscle test with foods and supplements to see what someone needs?
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    Quote Originally Posted by health4life24 View Post
    Hey bro, have a question. When people come out to see you, do you muscle test with foods and supplements to see what someone needs?
    Muscle testing I have mastered to accuracy of 98% as i have proved time and time again. Even the skeptics minds are changed. The technique I use is not used by traditional testers and allows me to further assesment.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by The Matrix View Post
    Muscle testing I have mastered to accuracy of 98% as i have proved time and time again. Even the skeptics minds are changed. The technique I use is not used by traditional testers and allows me to further assesment.
    That's cool! So through muscle testing, you know what supplements and diet someone needs to be on? I used to go to a holistic doctor that did muscle testing. I'm wondering that if you put different food and supplement items within someone's energy field if you could tell whether it was beneficial or not. Would help eliminate allot of guessing.
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    Some more info regarding this topic.

    I have been looking into P5P. The active form of Vitamin B6.

    If you have Mortons toe , toe next to big toe is longer than big toe ,this means you can't convert pyrodoxine into pyrodoxine 5 phosphate.

    I have this.

    I have figured out that folic acid is useless for those who have high histamine as this increases histamine levels even further. Also if you have MTHFR mutation this form of folate will do you no good. So you need to be using L-5-methyl tetrahydrofolate (L-5-MTHF).


    And in regards to vitamin B6 many people cannot convert it into its active form P5P in the liver due to medications (high blood pressure, arthritic meds), genetics, and any diseases they may have. So the P5P form needs to be used.

    P5P is the coenzyme for all enzymes involved in the conversion process for amino acids. P5P is also needed for hemoglobin production as well as for fatty acid and prostaglandin metabolism. It is also necessary for neurotransmitter production. It is also necessary for healthy functioning of the immune system and proper production of Red Blood Cells.

    Finally cyanocobalmin on its own isnt effective because the liver converts this to the active form methycobalamin. And this conversion again isnt always good depending on the individual. Methycobalamin protects brain cells, regenerates nerve tissues, improves methylation and gives you energy. So you need something like B12 Extreme or Methy B12 injections.
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    Quote Originally Posted by MetalMX View Post
    Some more info regarding this topic.

    I have been looking into P5P. The active form of Vitamin B6.

    If you have Mortons toe , toe next to big toe is longer than big toe ,this means you can't convert pyrodoxine into pyrodoxine 5 phosphate.

    I have this.

    I have figured out that folic acid is useless for those who have high histamine as this increases histamine levels even further. Also if you have MTHFR mutation this form of folate will do you no good. So you need to be using L-5-methyl tetrahydrofolate (L-5-MTHF).


    And in regards to vitamin B6 many people cannot convert it into its active form P5P in the liver due to medications (high blood pressure, arthritic meds), genetics, and any diseases they may have. So the P5P form needs to be used.

    P5P is the coenzyme for all enzymes involved in the conversion process for amino acids. P5P is also needed for hemoglobin production as well as for fatty acid and prostaglandin metabolism. It is also necessary for neurotransmitter production. It is also necessary for healthy functioning of the immune system and proper production of Red Blood Cells.

    Finally cyanocobalmin on its own isnt effective because the liver converts this to the active form methycobalamin. And this conversion again isnt always good depending on the individual. Methycobalamin protects brain cells, regenerates nerve tissues, improves methylation and gives you energy. So you need something like B12 Extreme or Methy B12 injections.
    i am already light years ahead of you

    THis will all be incorportate in to ones recommendations to cicumvent all of these chemical alterations. LET the experts do the thinking and you take a break from things. This will all be explained when time comes. When you are the patient you need to put trust into the treating medical practioner. i am telling you learn from my mistakes because it will only add more stress. ro many people get information over load. i have been to the worlds leading expert on methylation and i was actually a patient many years ago. From that time i have grown leaps and bounds in understanding the genetic mutations that occur and how to circumvent them. just sit back and relax and enjoy life and let the person treating you do their jobs. When it comes to methylation it gets extremely complicated and in some cases certain supplements that are normally used can be poison to the system.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by The Matrix View Post
    i am already light years ahead of you

    THis will all be incorportate in to ones recommendations to cicumvent all of these chemical alterations. LET the experts do the thinking and you take a break from things. This will all be explained when time comes. When you are the patient you need to put trust into the treating medical practioner. i am telling you learn from my mistakes because it will only add more stress. ro many people get information over load. i have been to the worlds leading expert on methylation and i was actually a patient many years ago. From that time i have grown leaps and bounds in understanding the genetic mutations that occur and how to circumvent them. just sit back and relax and enjoy life and let the person treating you do their jobs. When it comes to methylation it gets extremely complicated and in some cases certain supplements that are normally used can be poison to the system.


    Im only in the very beginnings of understanding all this.

    Yeah your right im in information overload, time to chilax a bit.

    Although once i get cured i will be very interested in possibly studying this. When i see people having so many problems medically and not getting the proper help i feel like i want to help them.

    Can you provide some examples of supplements that could be hazardous?
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    BUMP.

    Any new findings on methylation?
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    Does MSM improve methylation? I've read conflicting studies. I hate swallowing big pills and MSM powder tastes way better than methionine. Methionine is not tolerable as a powder, instant gag reflex!
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    Quote Originally Posted by LeanGuy View Post
    Does MSM improve methylation? I've read conflicting studies. I hate swallowing big pills and MSM powder tastes way better than methionine. Methionine is not tolerable as a powder, instant gag reflex!
    I think that methylation can be improved if molybednum and MSM are in proper balance because sulfur can deplete moly and moly is needed to keep methylation going as it is needed to convert sulfites to sulfates. But over all sam-e is the best for undermethylators provided proper b-12 and folate levels are present.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by The Matrix View Post
    I think that methylation can be improved if molybednum and MSM are in proper balance because sulfur can deplete moly and moly is needed to keep methylation going as it is needed to convert sulfites to sulfates. But over all sam-e is the best for undermethylators provided proper b-12 and folate levels are present.
    Cool, I take moly every day. For me sam-e increases anxiety after a few weeks... probably due to increased norepinephrine.
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    Quote Originally Posted by The Matrix View Post
    But over all sam-e is the best for undermethylators provided proper b-12 and folate levels are present.
    How is the combo of sam-e, methylfolate and methyl b-12 together?
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    Quote Originally Posted by Gutterpump View Post
    How is the combo of sam-e, methylfolate and methyl b-12 together?
    I recomend people on methy -12 and methyl folate first and then if no better then add in sam-e after a month or so..
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    I just started P5P and felt great after first dose. Mood up, my hands and body felt so warm and my muscles filled out, its probably because of my long term B6 deficiency in terms of an inability to convert regular B6 into the active P5P form. So the P5P form is great since it'll be boosting my serotonin as well.

    I will also be adding Folinic Acid 1mg and Methylcobalamin 5mg sublinguals + Moly to this undermethylation reigm which im about to order.

    Also i will be doing regular vitamin C and Glutathione IV pushes (2 amps) which my doctor thought would be a good idea with my chemical sensitivies and liver detoxification issues.
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    Better stock up on your P5P. Like all good supps that work, the FDA decided to make it a drug (or is in the process of banning it as a natural supp), so it will soon only be available via prescription.
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    Quote Originally Posted by Gutterpump View Post
    Better stock up on your P5P. Like all good supps that work, the FDA decided to make it a drug (or is in the process of banning it as a natural supp), so it will soon only be available via prescription.
    Nah not P5P ..
    Good thing I work for a MD no worrys there HAAH
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by MetalMX View Post
    I just started P5P and felt great after first dose. Mood up, my hands and body felt so warm and my muscles filled out, its probably because of my long term B6 deficiency in terms of an inability to convert regular B6 into the active P5P form. So the P5P form is great since it'll be boosting my serotonin as well.

    I will also be adding Folinic Acid 1mg and Methylcobalamin 5mg sublinguals + Moly to this undermethylation reigm which im about to order.

    Also i will be doing regular vitamin C and Glutathione IV pushes (2 amps) which my doctor thought would be a good idea with my chemical sensitivies and liver detoxification issues.
    If you like P5P
    you will love Pyridoxamine
    ---------------------------------------------------------------------\\\
    http://www.lef.org/Vitamins-Suppleme...mine-Caps.html


    There are three different forms of vitamin B6 (pyridoxine, pyridoxal, pyridoxamine). All are important and can be converted in the body to the active form of B6 called PLP or P5P which the body uses in many pathways. The pyridoxamine form is considered to be the most potent antiaging form because of its ability to enhance glucose metabolism, quench toxic free radicals1, and help block formation of advanced glycation end-products (AGEs).

    .
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    in the United States, the FDA ruled in January 2009 that pyridoxamine must be regulated as a pharmaceutical drug because it is the active ingredient in Pyridorin, a drug designed to prevent the progression of diabetic nephropathy.[1] Consequently, pyridoxamine can no longer be marketed in the United States as a dietary supplement.
    Another one bites the dust....stock up!
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    I remember a study about the use of Zantac because its a H2 Antagonist & will block the production & release of histamine, lowering the affects of the Histadelia

    It was originally posted on an acne forum years back

    Google "ACNE THE NEW THEORY" & you will see it, I cant post any links yet apparently


    & any thoughts on it?
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    As far as P-5-P, L-Methylfolate, Methylcobalamin, Niacinamide go..... Any recommended doses?

    Would really appreciate some input... Im new to this whole Undermethylation process but I KNOW for a fact that I am Histadelic, I almost fell out when I was reading the symptoms because they fit me to a TEE
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    Quote Originally Posted by SENSEZFAIL View Post
    As far as P-5-P, L-Methylfolate, Methylcobalamin, Niacinamide go..... Any recommended doses?

    Would really appreciate some input... Im new to this whole Undermethylation process but I KNOW for a fact that I am Histadelic, I almost fell out when I was reading the symptoms because they fit me to a TEE
    Before supplementing I have all my clients have some kind of clinical basis for recommending these supplements. When dealing with methylation you need to know what the hell you are doing other wise it can make matters even worse.
    Metal MX has that validation which makes it much more easier to recommend for his individual need ..
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    How can I go about that?

    Certain testing that I should ask for?
    PM you exact symptoms?

    Im at a desperate stage right now......
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    Quote Originally Posted by SENSEZFAIL View Post
    How can I go about that?

    Certain testing that I should ask for?
    PM you exact symptoms?

    Im at a desperate stage right now......
    If you have insurance then do the Genova ONE test once you get results PM ME.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    No type of insurance, Im 19 & just got laid off from my first job... Generally how much would a test be minus insurance & how standard are they as far as where you can get them done at?

    Also, how much of an impact does a Histidine diet have on this issue? Ive read to avoid foods such as Chicken, Beef, High Protein & even things like Spinach & Peas? This has been an issue for me seeing as I already feel I have a dairy & wheat allergy possibly caused by leaky gut from a Th2:Th1 imbalance
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    You read too much as do many people and need to sift through the nonsense and what is fact. If you have leaky gut then you need to start treating with it, but with out knowing ones biochemistry it could end up through people into seizures if one trys to supplement the wrong thing. To me it sounds like you are overstressed and in a bad position right now. In your case stress management would be the most logical choice as well as supplements to calm your sympathetic nervous system down. Try to relax before going to bed at night by staying off the computer and trying to self diagnose your self. When I first start handling people this is the best piece of advice I can give them is to let the experts do the thinking that is they get paid for. If you do not trust your health advisier then find another one..You can hire and fire at will. The power is yours. i have been in your shoes and it can be a very difficult time in life, but where there is a will there is a way to get back to your wellness. Take one step at a time and look at all the positive things you have going in life instead of focusing on the negative.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    No, It's much deeper then Leaky Gut & it won't let me send you a PM... Is there any way I could contact you just so you can hear me out?
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    Quote Originally Posted by SENSEZFAIL View Post
    No, It's much deeper then Leaky Gut & it won't let me send you a PM... Is there any way I could contact you just so you can hear me out?
    Trust me when I start digging there are alot of issue that are resulting in leaky gut ..I look at the person from all angles even their child hood if there is trama and current living situation and everything ..there are also could be a hidden factor such as infection that has not been discovered or dybiosis
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Well it seems after only three days of use of the LMethylFolate, MethylB12 and P5P i am noticing improvments. I went through what i would call a "healing crisis" on day two and felt worse then ever with bone pains and flu like feeling then this subsided and i woke up feeling pretty damn good!

    My muscles have like popped out or started growing or something i duno but i like it, its literally noticable after 2-3 days. I have also gotten some dull liver aches like my liver is kickstarting itself back up.

    All i can say is i hope to see a lot more improvments, Thanks Matrix. Its amazing what a little of the right supplementation can do.
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    Quote Originally Posted by MetalMX View Post
    Well it seems after only three days of use of the LMethylFolate, MethylB12 and P5P i am noticing improvments. I went through what i would call a "healing crisis" on day two and felt worse then ever with bone pains and flu like feeling then this subsided and i woke up feeling pretty damn good!

    My muscles have like popped out or started growing or something i duno but i like it, its literally noticable after 2-3 days. I have also gotten some dull liver aches like my liver is kickstarting itself back up.

    All i can say is i hope to see a lot more improvments, Thanks Matrix. Its amazing what a little of the right supplementation can do.
    If more people and Dr's would start recognising this..After about 4-5 weeks you should really kick in. I just had a lady come to me yesterday with dna testing as well. I told her I did not want to see the results untill I got done with her muscle testing. Amazingly after i tested the supplements and told her what supplements she tested for. Then after looking at the results the muscle testing showed methy folate , methyl b-12, but not TMG and P5P.
    Amazing she had mutation of mthfrr and also methione synthase on her DNA report, When I showed her the results she tripped out. I do this every time to prove my point that its not a psudo science but based upon real validity.

    What did you dr say when you presented what supplements i recommended and we never even conversed LOL Plus you are not on a boat load of stuff just what body requires.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Quote Originally Posted by The Matrix View Post
    If more people and Dr's would start recognising this..After about 4-5 weeks you should really kick in. I just had a lady come to me yesterday with dna testing as well. I told her I did not want to see the results untill I got done with her muscle testing. Amazingly after i tested the supplements and told her what supplements she tested for. Then after looking at the results the muscle testing showed methy folate , methyl b-12, but not TMG and P5P.
    Amazing she had mutation of mthfrr and also methione synthase on her DNA report, When I showed her the results she tripped out. I do this every time to prove my point that its not a psudo science but based upon real validity.

    What did you dr say when you presented what supplements i recommended and we never even conversed LOL Plus you are not on a boat load of stuff just what body requires.

    He didn't say much besides that he knows its for methylation. The only thing he saw was the lack of B6 P5P on the ONE test i don't think he noticed my folic acid/B12 problem on their, i was the one who asked him for the MethylB12 and Folinic Acid for an order form. He seemed like he was rushing with me when i first saw him but when he saw my mum he was taking his time and did the biofeedback testing with her but not me. But ill ask him to do it next time. I hate doctors ****ing rushing with me when i'm paying them a ****load of money.

    The supps are definitly helping. I know i have a problem with nerve damage but i don't know the cause.

    Did my doctor think for a second that my numbness and tingling, loss of sensation and muscle weakness could be attributed to nerve damage? No. Bascially all GP's i have seen completely useless id get more help from a deaf drunken hobo.

    My final conclusion Matrix is this could be pernicious anemia but i'll have to test for it, my tongue is red and swollen a bit seems like a symptom of the disease. Because my grandmother has low serum folic acid and B12 and is getting her intrinisic factor antibodies tested and parietal cell antibodies and my mum has low b12 too. Both my mum and grandmother have tingling and my mother has mild sense reduction and slight neurological symptoms. It would be a good idea to rule it out.

    Or it could be a really bad cause of undermethylation just by itself.

    Main thing is things are getting better. You should be the doctor's doctor my man.

    I think people should get use to regular doctors being excellent at diagnosing only acute medical problems (which they are) that are life and death and nothing else. Any other problems... nope can't help you their.

    What kind of DNA testing did she undergo?
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    This thread should be a sticky.


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    Quote Originally Posted by MetalMX View Post
    He didn't say much besides that he knows its for methylation. The only thing he saw was the lack of B6 P5P on the ONE test i don't think he noticed my folic acid/B12 problem on their, i was the one who asked him for the MethylB12 and Folinic Acid for an order form. He seemed like he was rushing with me when i first saw him but when he saw my mum he was taking his time and did the biofeedback testing with her but not me. But ill ask him to do it next time. I hate doctors ****ing rushing with me when i'm paying them a ****load of money.

    The supps are definitly helping. I know i have a problem with nerve damage but i don't know the cause.

    Did my doctor think for a second that my numbness and tingling, loss of sensation and muscle weakness could be attributed to nerve damage? No. Bascially all GP's i have seen completely useless id get more help from a deaf drunken hobo.

    My final conclusion Matrix is this could be pernicious anemia but i'll have to test for it, my tongue is red and swollen a bit seems like a symptom of the disease. Because my grandmother has low serum folic acid and B12 and is getting her intrinisic factor antibodies tested and parietal cell antibodies and my mum has low b12 too. Both my mum and grandmother have tingling and my mother has mild sense reduction and slight neurological symptoms. It would be a good idea to rule it out.

    Or it could be a really bad cause of undermethylation just by itself.

    Main thing is things are getting better. You should be the doctor's doctor my man.

    I think people should get use to regular doctors being excellent at diagnosing only acute medical problems (which they are) that are life and death and nothing else. Any other problems... nope can't help you their.

    What kind of DNA testing did she undergo?
    My specualtion is hypomethylation and hypothyroid are both at core source as well as stress (over traning, under eating, steroid use, enviormental effect) causing the accelerated mutations to be more apparent now then 40 years down the road. As both of these things run in your family history (genetic) and can geoghaphical stress such as powerlines, and power stations may be mold exposure could have been all contributing factors. Putting over 12 hours of research and correspondance back and forth to come up with viable scenerio
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Pretty much...

    Matrix do you know any links or pdfs or anything of the sort with diagrams of the methylation cycle and what it actually involves on an indepth manner?.

    I could only find one diagram couple months ago on a supplement website where it basically showed methylation is involved in - Energy production, mood (neurotransmitters) , healing, detoxification via production of glutathione, Immunity and DNA.

    Their doesn't seem to be much concrete data about it on the web, yet it is so vital for life.

    And how did you figure out mold exposure?

    I know i was always in one place for 2 years and i didn't get out much of that place (besides the gym). and the food i was eating was always cold from the fridge and out of cans and it was left out in the kitchen at times without any wrapping paper... so the mold issue would make sense. Not to mention i had really bad candida yeast infections and subsequent symptoms.
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    Quote Originally Posted by MetalMX View Post
    Pretty much...

    Matrix do you know any links or pdfs or anything of the sort with diagrams of the methylation cycle and what it actually involves on an indepth manner?.

    I could only find one diagram couple months ago on a supplement website where it basically showed methylation is involved in - Energy production, mood (neurotransmitters) , healing, detoxification via production of glutathione, Immunity and DNA.

    Their doesn't seem to be much concrete data about it on the web, yet it is so vital for life.

    And how did you figure out mold exposure?

    I know i was always in one place for 2 years and i didn't get out much of that place (besides the gym). and the food i was eating was always cold from the fridge and out of cans and it was left out in the kitchen at times without any wrapping paper... so the mold issue would make sense. Not to mention i had really bad candida yeast infections and subsequent symptoms.
    just not looking in right places.
    http://www.ihop-net.org/UniPub/iHOP/...?pmid=16445837

    http://www.heartfixer.com/AMRI-Nutrigenomics.htm
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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