Recent thread about Phil, he have a bone problems.
For many years he was using cortisol and DIM
Doubt if cortisol was causing problems, since he used physiological size doses.
But he was using DIM to control E2, Estrodial.
DIM is not AI, it helps with metabolites of E1 (estriol)
my guess is that his E1 was real low for long time.
I do not remember him testing for E1, he always checked E2 only.