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no libido !!

  1.  08-01-2008  05:58 PM
    Registered User Roms's Avatar
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    no libido !!


    Hi Guys,

    I am currently treated for hypopituitarism meaning I am secondary (prednisolone,dhea,armour and HCG 800 ius EOD)

    After a few months now on hcg only where I feel I am doing pretty good and my T levels seem ok as well as my E2 levels ... I am trying to find other causes that would explain my complete lack of sex drive.

    You know, I have been on TRT with very high levels of testosterone and I have been high and low on E2 but in every case I would never have any sexual thoughts or morning wood,never ...TT and free over the range with E2 at about 28 wouldn't do the trick.

    Looking back on one of my latest result something puzzles me, I have a very high progesterone level : 1.11 ng/ml (0.1-0.65).

    From Dr Lam site, I understand that high progesterone in men can block the convertion from Testosterone to DHT thus creating a low level of DHT that would lead to a low libido.

    Sadly, informations on high progesterone in men are hard to find and I don't have yet a DHT test result.

    Can you confirm that low DHT means low libido ?

    Have you heard anything like that before and do you know how to reduce progesterone ?

    Thank you for your input.



  2.  08-01-2008  10:55 PM
    Registered User brentf13's Avatar
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    Well DHT does mean low libido. If you'd like to see if that's your issue try Proviron. If that doesn't fix you you're probably in the same boat as me. I have the same exact issue only I'm 100% fixed for the first few days of TRT and then the same. I've done this several times with the same result with E2 in check. It sounds like I'm responding to the dopamine rush from starting TRT which fades quickly. Bottom line is I respond to the initial antidepressant response of T but the T itself does nothing for me. (My TT, free T were off the map on my last labs and E2 28.) Against my better judgment I just started taking Cymbalta and I've been having a flicker of libido. I've also read a few posts where guys have been put on an AD and there T went up. Depression can cause poor HPTA function. Then again low T can cause depression. It's a chicken or the egg problem. I decided to treat both and see how I make out. Luckily if you're on T and you want to try an AD you shouldn't suffer bad sexual sides. Some ADs are notorious for lowering free T thus inducing dysfunction.

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  3.  08-02-2008  12:42 AM
    Registered User Hyde12's Avatar
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    Originally Posted by brentf13 View Post
    Well DHT does mean low libido. If you'd like to see if that's your issue try Proviron. If that doesn't fix you you're probably in the same boat as me. I have the same exact issue only I'm 100% fixed for the first few days of TRT and then the same. I've done this several times with the same result with E2 in check. It sounds like I'm responding to the dopamine rush from starting TRT which fades quickly. Bottom line is I respond to the initial antidepressant response of T but the T itself does nothing for me. (My TT, free T were off the map on my last labs and E2 28.) Against my better judgment I just started taking Cymbalta and I've been having a flicker of libido. I've also read a few posts where guys have been put on an AD and there T went up. Depression can cause poor HPTA function. Then again low T can cause depression. It's a chicken or the egg problem. I decided to treat both and see how I make out. Luckily if you're on T and you want to try an AD you shouldn't suffer bad sexual sides. Some ADs are notorious for lowering free T thus inducing dysfunction.
    I would love to see how the Cymbalta works for you in the long run. SSRIs and SNRIs have a long history of lowering libido and causing ED in men. Wellbutrin (Buproprion) is another story.

  4.  08-02-2008  12:54 AM
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    Tried Wellbutrin once for 2 months and it did nothing but make me break out horrible and gave me nasty hot flashes. Cymbalta I researched quite a bit and the sexual sides seem to be just about zip. (I researched actual reviews from people using it not what their website says.) A funny thing about those drugs is if libido is your problem sometimes it has the opposite effect.

    Anyway I'm on T cyp, Proviron, HCG, and Adex and zero luck so far. You know whats funny is Tribex worked great for me for about two months. So far that's been my best experience.

  5.  08-02-2008  01:09 AM
    Banned Iron Lungz's Avatar
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    Coming back from my last stint in the sand, my DR put me on Wellbutrin because I was experiencing a lot of PTSS. Before taking it, I had horrible nightmares/night terrors and would sweat like no other. After a few weeks on Wellbutrin, it got worse. Even to the point to where I would feel wired all day and night, could not sleep... but damn I could get a raging boner for no reason. I stopped taking that crap and a few weeks later I was back to normal. No more nightmares, sweats... but the raging boners stayed! Crazy drugs - That's exactly why I hate taking anything that affects the brain.

  6.  08-02-2008  04:51 AM
    Registered User Roms's Avatar
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    If high progesterone is the cause blocking testosterone convertion to DHT then how to reduce high progesterone ?

    If proviron was working,would it be used as a lifelong treatment at a dosage of 25 mg per day ?

  7.  08-02-2008  05:22 PM
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    Originally Posted by Hyde12 View Post
    I would love to see how the Cymbalta works for you in the long run. SSRIs and SNRIs have a long history of lowering libido and causing ED in men. Wellbutrin (Buproprion) is another story.

    I'm trying an SSRA (stablon - much better than any SSRI imo) with a bit of wellbutrin and some HCG (even though my LH wasn't that bad) and things are definately much improved. Still don't think that HCG is the full answer for me though, but bloodwork will tell. Things definately seemed to be improving libido wise when I started the stablon though, I think there's definately something to that..I'm getting random wood now throughout the day and having a lot of dreams about sex at night..that hasn't been happening to me since I was in my teens, or since I tried epistane/on cycle (for the first couple weeks of it).

  8.  08-02-2008  05:27 PM
    Registered User Gutterpump's Avatar
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    Originally Posted by Iron Lungz View Post
    Coming back from my last stint in the sand, my DR put me on Wellbutrin because I was experiencing a lot of PTSS. Before taking it, I had horrible nightmares/night terrors and would sweat like no other. After a few weeks on Wellbutrin, it got worse. Even to the point to where I would feel wired all day and night, could not sleep... but damn I could get a raging boner for no reason. I stopped taking that crap and a few weeks later I was back to normal. No more nightmares, sweats... but the raging boners stayed! Crazy drugs - That's exactly why I hate taking anything that affects the brain.
    I've tried up to 450mg of wellbutrin and it never got me that agitated or wired. I wonder if I have poor adrenals atm, or maybe just didn't respond well to it though. Definately liking a mild dose of it now though at 150mg. I can tell a mild change when I forget a dose.

  9.  08-02-2008  05:28 PM
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    reducing prolacting......

    cabergoline .5mg every 3 days or every other day if need be.

    this may help you with that problem

  10.  08-02-2008  07:44 PM
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    How's your thyroid... can have a profound effect on libido

  11.  08-02-2008  08:22 PM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Roms View Post
    Hi Guys,

    I am currently treated for hypopituitarism meaning I am secondary (prednisolone,dhea,armour and HCG 800 ius EOD)

    After a few months now on hcg only where I feel I am doing pretty good and my T levels seem ok as well as my E2 levels ... I am trying to find other causes that would explain my complete lack of sex drive.

    You know, I have been on TRT with very high levels of testosterone and I have been high and low on E2 but in every case I would never have any sexual thoughts or morning wood,never ...TT and free over the range with E2 at about 28 wouldn't do the trick.

    Looking back on one of my latest result something puzzles me, I have a very high progesterone level : 1.11 ng/ml (0.1-0.65).

    From Dr Lam site, I understand that high progesterone in men can block the convertion from Testosterone to DHT thus creating a low level of DHT that would lead to a low libido.

    Sadly, informations on high progesterone in men are hard to find and I don't have yet a DHT test result.

    Can you confirm that low DHT means low libido ?

    Have you heard anything like that before and do you know how to reduce progesterone ?

    Thank you for your input.
    Your progesterone levels aren't very high. I take progesterone daily, and my levels are more than double yours (2.9). I have DHT is in the upper range (75). Progesterone helps your nads produce testosterone.

    Like you, I'm on HCG only, but my protocol is 1500 IUs E3D. I also have E2 in check (23). Have you tested DHT? Also, what are your numbers for testosterone (free/total) and E2?

  12.  08-02-2008  08:38 PM
    Registered User Hyde12's Avatar
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    Originally Posted by colkurtz_spf View Post
    Your progesterone levels aren't very high. I take progesterone daily, and my levels are more than double yours (2.9). I have DHT is in the upper range (75). Progesterone helps your nads produce testosterone.

    Like you, I'm on HCG only, but my protocol is 1500 IUs E3D. I also have E2 in check (23). Have you tested DHT? Also, what are your numbers for testosterone (free/total) and E2?
    I can't believe you would actually WANT to supplement with progesterone.Then again, everyones body is different. You are better off supplementing with Pregnenolone because it is more of a balancing hormone. Have you read the experience Leanguy had with Progesterone?

  13.  08-02-2008  11:06 PM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Hyde12 View Post
    I can't believe you would actually WANT to supplement with progesterone.Then again, everyones body is different. You are better off supplementing with Pregnenolone because it is more of a balancing hormone. Have you read the experience Leanguy had with Progesterone?

    My doctor prescribes the progesterone. He believes it enhances the effects of HCG - it's a more direct path than pregnenolone. I've been on it for nearly a year and have had no problem with it. It may be the reason I'm doing well on lower doses of HCG. My total T is 1144 - I feel great and my libido is through the roof. I'm not saying it's for everyone. I get tested every 90 days, and I'm under the supervision of an excellent doctor. What I am saying is that a progesterone level of 1.1 is not high.

  14.  08-03-2008  09:32 AM
    Registered User Hyde12's Avatar
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    Originally Posted by colkurtz_spf View Post
    My doctor prescribes the progesterone. He believes it enhances the effects of HCG - it's a more direct path than pregnenolone. I've been on it for nearly a year and have had no problem with it. It may be the reason I'm doing well on lower doses of HCG. My total T is 1144 - I feel great and my libido is through the roof. I'm not saying it's for everyone. I get tested every 90 days, and I'm under the supervision of an excellent doctor. What I am saying is that a progesterone level of 1.1 is not high.
    Sounds like you have a good doctor. Are you seeing Dr. Crisler? My Endocrinologist is an idiot.

  15.  08-03-2008  01:11 PM
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    I always thought that pregnenalone is mainly converted to progesterone in the body first before anything else.

    My own experience with preg @ 50mg ed, doubled my progesterone to twice the upper limit on my bloodwork, but I only noticed postive effects and continue to supplement with this.

  16.  08-03-2008  01:31 PM
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    Originally Posted by Hyde12 View Post
    Sounds like you have a good doctor. Are you seeing Dr. Crisler? My Endocrinologist is an idiot.
    Hyde,

    What are your T levels now?

  17.  08-03-2008  05:10 PM
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    Originally Posted by darkblue1 View Post
    Hyde,

    What are your T levels now?
    around 800.

  18.  08-03-2008  06:18 PM
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    Originally Posted by Hyde12 View Post
    Sounds like you have a good doctor. Are you seeing Dr. Crisler? My Endocrinologist is an idiot.
    I think I do have a good doctor. His practice is in South Florida. If you're interested PM me.

  19.  08-04-2008  07:47 AM
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    Originally Posted by colkurtz_spf View Post
    Your progesterone levels aren't very high. I take progesterone daily, and my levels are more than double yours (2.9). I have DHT is in the upper range (75). Progesterone helps your nads produce testosterone.

    Like you, I'm on HCG only, but my protocol is 1500 IUs E3D. I also have E2 in check (23). Have you tested DHT? Also, what are your numbers for testosterone (free/total) and E2?
    Thanks a lot for your interest.
    My numbers are all in the top of the range exept estradiol at 25 or a bit less. I will soon have updated numbers.

    I don't have yet my DHT results but according to my good testosterone/estradiol levels and and my complete lack of libido, I am really hoping to find a low DHT as the missing piece of the puzzle.

    I take 800 ius EOD of HCG coming from 400ius ED because I am not sure HCG stays as effective when you dose it every 3 days.It's more or less the same weekly dosage as you take I think.

    One of my last test in the morning after I had a 500 ius HCG shot during the evening showed a total test of 836.28ng/dl.

    Do you know if DHT participate on how you feel as well ?

    If low DHT was my issue, would the use of proviron be one of the best option to increase it ?

  20.  08-04-2008  10:17 AM
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    Proviron won't increase your DHT it is DHT. It would be something that you could try and see if it picks up your libido. It will also free up more T and decrease E2 further.

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