3aHSD converts Androstanediol to Stanolone...

  1. 3aHSD converts Androstanediol to Stanolone...


    Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism . Best Practice & Research Clinical Endocrinology & Metabolism , Volume 15 , Issue 1 , Pages 79 - 94 Y . Jin

    5α-DHT is formed from circulating testosterone by the action of the type 2 steroid 5α-reductase (5α-R) and its action is terminated by the action of a reductive 3α-hydroxysteroid dehydrogenase (3α-HSD) which forms the weak androgen 3α-androstanediol. Oxidative 3α-HSD isoforms, however, can provide an alternative source of potent androgens by converting 3α-androstanediol to 5α-DHT.


    Over at bb.com they will tell you that 3aHSD is selective, and that may be somewhat true for ONE isoform, but never is the situation cut and dry that way.


  2. Quote Originally Posted by LegalGear View Post
    Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism . Best Practice & Research Clinical Endocrinology & Metabolism , Volume 15 , Issue 1 , Pages 79 - 94 Y . Jin

    5α-DHT is formed from circulating testosterone by the action of the type 2 steroid 5α-reductase (5α-R) and its action is terminated by the action of a reductive 3α-hydroxysteroid dehydrogenase (3α-HSD) which forms the weak androgen 3α-androstanediol. Oxidative 3α-HSD isoforms, however, can provide an alternative source of potent androgens by converting 3α-androstanediol to 5α-DHT.


    Over at bb.com they will tell you that 3aHSD is selective, and that may be somewhat true for ONE isoform, but never is the situation cut and dry that way.
    what the heck did you just say? man, that went right over my head.
    GOD, FAMILY, COUNTRY!!!
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