Ok, Methyl 1-D is always being questioned, so I thought I would write a quick explanation on the science behind it and why the knock off products are no where near as good. You can get an idea of the time spent on the product.
Methyl 1-D isn't just DHEA, we use a DHEA Ethanoate Ester. Ethanoate Esters help improve functional absorbtion while (my theory) blocking some of the effects of Sulfotransferase. Sufation is the main way Androsterones get inactivated in the body and the Ethanoate Ester occupies the same spot as the Sufate, so in theory it should increase the bioavailability of the molecule. Sulfation is the main reason you need to take a thousand milligrams of a diol to make it effective. Blocking Sulfation was started in this industry by US!
Ingredient # 1 - ATD
ATD blocks aromatase and keeps more of the conversion process in check, so more DHEA is available to convert into Testosterone.
Ingredient # 2 - Ellagic Acid
A natural SERM derivied from raspberries. Ellagic Acid would serve to block any intrinsic estrogenic effects of the 5-ENE molecule.
Ingredient # 3 - Milk Thistle
Milk Thistle isn't just for livers, it blocks the second big route of excretion, Glucoronidation. The standardized Milk Thistle we use, inhibits Glucoronidase.
Ingredient # 4 - Luteolin
Luteolin is a Sulfotransferase competitive inhibitor. Meaning it soaks up the Sulfotransferase enzyme so it can't act on the hormone. A HUGE percent of 3b-ol steroids get sulfated, which makes them inactive. Luteolin is a strong binder to Sulfotransferase, much stronger than a prohormone.
Ingredient # 5 - Stinging Nettle Extract
We all know that this blocks SHBG, freeing up more testosterone, but the full plant extract is also a 5aReductase inhibitor, which means less converstion to DHT and much higher androgen levels.
Ingredient # 6 - Coleus Forskolin
CF upregulates 3bHSD, the enzyme responsible for converting the 3b-ol to the active. Since the gut contains a boat load of 17bHSD much of the oral hormone is turned into 5-AD, which if you block the estrogenic effects (which we have) is pretty potent.
Ingredient # 7 - Caprylic Acid
This is one half of Receptor, which makes the cells more sensitive to androgens.
Ingredient # 8 - Zinc Aspertate
The Z in ZMA is what does all the work. Zinc increases the effeciency of the Androgen receptor fingers.
Ingredient # 9 - Piperine
Piperine increases absorbtion by blocking Glucoronidase as well as increasing intestinal permeability.
So, when someone says "M1D is ****, it's just DHEA" post them this write up please...
Honestly, all hormones (except the 17aMethyl) could benefit from our delivery methods (patent pending). Making the stuff you have work better is what we are all about. We are not perfect, but as you can see I am quite proud of Methyl 1-D!