From some of the logs about there some people experience androgenic side effects such as prostate problems and high blood pressure.
I used Natadrol last year and after about 10 days felt fantastic with a real sense of well-being/alpha male feeling, high libido, all day muscle pumps, etc. but went to the doctor's for a regular check-up and my blood pressure was 160/105. I normally have slightly high bp at 130/80 but nothing near the level it was when using Natadrol. I stopped Natadrol straight away and went back to the doctor's a week later and my bp was back to its' normal 130/80.
If you are prone to androgenic side effects when using PHs/steroids then you may experience them with Natadrol so it's worth being careful.