[Samson4]

It's pretty well known that igf is eventually "figured out" by the body. My question is, why would a low dose cycle be any different? Also, how much natural igf do we have on average?

[wrangler3456]

Our body naturally produces around 1mcg a day

[pudzian2]

Originally Posted by Samson4

It's pretty well known that igf is eventually "figured out" by the body. My question is, why would a low dose cycle be any different? Also, how much natural igf do we have on average?

by "figured out" do you mean that it recognizes exogenous IGF-1 and therefor possibly downregulates natural production?

or are you askign whether after a certain amount of time using IGF-1, the body stops reacting to it's effects?

[Samson4]

The body stops reacting to exogenous igf.

[pudzian2]

Originally Posted by Samson4

The body stops reacting to exogenous igf.

I haven't read too much about that. Although no matter what systems we talk about, the body always tends to create a state of homeostasis. (or at least tries)....

There really hasnt been too much write up that i've seen suggesting that exogenous IGF-1 shuts down natty production (and if it does, people dont seem to concerned about bouncing back). Taking too much IGF-1 at once is just wasteful, so that is why people are having better success with low dose, long cycles (from what I have read). i am trying one for myself. I do however plan on running some GH boosters like pGH occasionally and coming off IGF-1 for a week or a few every so often just becuase I feel that IF it does hamper natty production of IGF or GH in any way, that will give the body some time to recovery.

Also, if concerned about IGF-1 loosing effect, coming off every so often will help refresh the receptors.

[Samson4]

That's what I was asking, so no matter how low you go with your dose, your body will eventually recognize the exogenous igf, and disable it? Causing the need to cycle it?

I'm trying to decide if it would be wiser to use 60mcg Mon,wed,friday for 4 weeks on 4 weeks off. Or use 20mcg mon,wed,friday for a longer cycle. I'm a competitive weightlifter and will be site injecting not just for strength, but for connective tissue strengthening and increased recovery.

[Samson4]

I almost forgot, I lift heavy mon,wed,friday. I do upperbody training in the morning and lower body in the evening. I'll be site injecting in my triceps and quads after the corresponding workout, very close to the knee and elbow joints.

[pudzian2]

Originally Posted by Samson4

I almost forgot, I lift heavy mon,wed,friday. I do upperbody training in the morning and lower body in the evening. I'll be site injecting in my triceps and quads after the corresponding workout, very close to the knee and elbow joints.

dont shoot it in the joint. Shoot it in the muscle as close as possible. dont stick the needle where you would for a cortisone shot.

I too use it for connective tissue repair and strength because I have some issues with my tendons (partial tears, tendinitis etc).

I think one other thing that has been proven (I may have read it somewhere) is that over time the body will upregulate IGF-1 binding protein which is to IGF-1 as SHBG is to testosterone.

[Samson4]

Yes, the shot will be in the quads and triceps as close as possible to the joint. It will end up being 15mcg per shot, twice in the morning and twice in the evening. I wonder how much of presence it will have, when it comes to homeostasis.

[pudzian2]

Originally Posted by Samson4

Yes, the shot will be in the quads and triceps as close as possible to the joint. It will end up being 15mcg per shot, twice in the morning and twice in the evening. I wonder how much of presence it will have, when it comes to homeostasis.

as far as the homeostasis comment, I would like to know as well. Unfortunately there hasnt been too much written about that. (that I have found at least)...

If you are using IGF-1LR3 then I don't even know if site injections are worth while. I do them anyway so as not to risk them being worthwile, but because of the LR3 I think they float around systematically a lot more than IGF-1 (no LR3)

[Samson4]

How coudd I include pegmgf into my igf cycle?

[pudzian2]

Originally Posted by Samson4

How coudd I include pegmgf into my igf cycle?

I haven't done too much research on it, however once you decide on a dose, I heard it was best used something like twice per week 24hours before training or something like that.