Mechano Growth Factor (MGF) and Insulin-Like Growth Factor-1 (IGF-1) Information Link

TheGame46 · 07-29-2006, 09:18 PM

Quote:

Originally Posted by CHAPS

Is the Igf-1 totally necessary? Or can we just run MGF on it's on?

You must remember that MGF only increases the number of staelite cells for use. Naturally you body uses another form of IGF very very similar to the systemic LR3 IGF available to then differentiation these new cells into components of adult muscle cells.

So is IGF necissary, NO I dont hink you have to have it b/c you have your own natural IGF and cna induce IGF productino through training but I think better results may be acheived using both, or using MGF in conjuction with AAS b/c they also induce differentiation

**Jayhawkk** · 07-29-2006, 09:29 PM

Since this continues on the sticky info i'm gonna copy this to the thread up there so there isn't scattered info on this all over the place.

TheGame46 · 07-29-2006, 09:35 PM

Ok just keep in mind this is unique to the PEGylated version. Could you edit the title so people know please?

**Jayhawkk** · 07-29-2006, 09:38 PM

Yeah, no foul meant Game. I've just been working hard on narrowing the info lately to make searching much easier.

That Dude · 09-14-2006, 01:32 PM

Your work is brilliant bro... Thanks for sharing! I have so much to read now... seriously thanks

logan22 · 10-09-2006, 03:41 PM

Quote:

Originally Posted by LakeMountD

Still the same info. The problem occurred in Dr. Goldspink's older studies. When he first began research on MGF he hypothesized that it was responsible for not only proliferation (brining in of myoblasts) but also for differentiation (activation of these myoblasts). This, however, proved to not be true in newer studies and actually it was wrong to a very large degree as it was found that not only did MGF not differentiate myoblasts but it actually inhibited myoblasts from differentiating (this is his newest hypothesis). They now say that IGF-1Ea is responsible for the differentiation, which is good for all the LR3 IGF-1 users out there. MGF still has its place as something that has a lot of potential, especially with the longer lasting PEGylated version coming out, but it will take much longer to figure out how to use it synergistically with LR3 IGF-1 since it does inhibit differentiation.

We basically have to determine how we can dose this stuff to where we get a large influx of myoblasts without inhibiting differentiation. I also still believe LR3 IGF-1 and MGF stacked together are the best way to go. With the large amount of IGF-1 we are getting, we need the extra myoblasts and with all the myoblasts being proliferated by the MGF, you are going to want the added anabolism.

You seem to be the Resident expert on IGF LR3 and MGF. This will be my first cycle of anything. Ive never been a fan of Steroids, but HGH, IGF, and MGF...interest me do to the fact they are natural functions of the body....just magnified. Any thoughts of a virgin stack of any of these or just alone? I was thinking HGH, but if the size comes for IGF LR3...maybe that is the more appropriate route....with a side of MGF? Thoughts?????

LakeMountD · 10-09-2006, 04:11 PM

I like LR3 IGF-1 the best personally, but then again have never tried hGH as I could never justify the price and the fact cycles have to be run for very long periods of time. Try getting 1-2mg of LR3 IGF-1 and run it at 20mg EOD or 30mg E3D and let me know how you liked it. Hunger should be way up, increased vascularity (through nitric oxide pathways), decrease in fat, slight increase in muscle mass, but this is the foundation that will be laid for later growth. You can also add in PEG-MGF 2x per week if you'd like. Search around professional muscle . com for some dosage schemes, we had some people trying it out over there who loved it.

logan22 · 10-09-2006, 04:52 PM

Quote:

Originally Posted by LakeMountD

I like LR3 IGF-1 the best personally, but then again have never tried hGH as I could never justify the price and the fact cycles have to be run for very long periods of time. Try getting 1-2mg of LR3 IGF-1 and run it at 20mg EOD or 30mg E3D and let me know how you liked it. Hunger should be way up, increased vascularity (through nitric oxide pathways), decrease in fat, slight increase in muscle mass, but this is the foundation that will be laid for later growth. You can also add in PEG-MGF 2x per week if you'd like. Search around professional muscle . com for some dosage schemes, we had some people trying it out over there who loved it.

Thanks.

IM...but site specific, bilateral or just quad and glute?

logan22 · 10-11-2006, 01:42 PM

Quote:

Originally Posted by LakeMountD

I like LR3 IGF-1 the best personally, but then again have never tried hGH as I could never justify the price and the fact cycles have to be run for very long periods of time. Try getting 1-2mg of LR3 IGF-1 and run it at 20mg EOD or 30mg E3D and let me know how you liked it. Hunger should be way up, increased vascularity (through nitric oxide pathways), decrease in fat, slight increase in muscle mass, but this is the foundation that will be laid for later growth. You can also add in PEG-MGF 2x per week if you'd like. Search around professional muscle . com for some dosage schemes, we had some people trying it out over there who loved it.

Also, I figure ill reconstitute both with AA. Then what do I backload my slin pins with and how much?

LakeMountD · 10-11-2006, 02:29 PM

Quote:

Originally Posted by logan22

Also, I figure ill reconstitute both with AA. Then what do I backload my slin pins with and how much?

PEG-MGF is water soluble, no need for AA.

logan22 · 10-13-2006, 02:53 PM

Quote:

Originally Posted by LakeMountD

PEG-MGF is water soluble, no need for AA.

Why EOD or E3D? Why not ED?

LakeMountD · 10-13-2006, 03:22 PM

Quote:

Originally Posted by logan22

Why EOD or E3D? Why not ED?

Receptor endocytosis, aka receptor down regulation

. But search the IGF-1 forum for posts by me and there is a thread about why EOD-E3D injections are best.

logan22 · 10-14-2006, 04:27 PM

Quote:

Originally Posted by LakeMountD

Receptor endocytosis, aka receptor down regulation

. But search the IGF-1 forum for posts by me and there is a thread about why EOD-E3D injections are best.

Do you have a link to it? I cant find the posting. So if I pin the MGF of Sunday, (everywhere) Then should I wait one day to pin the LR3, then every other day? Would that work

Sun MGF 250mcg
Tues, Thurs, Sat LR3 40mcg?

How does that sound?

logan22 · 10-17-2006, 12:37 PM

Quote:

Originally Posted by logan22

Do you have a link to it? I cant find the posting. So if I pin the MGF of Sunday, (everywhere) Then should I wait one day to pin the LR3, then every other day? Would that work

Sun MGF 250mcg
Tues, Thurs, Sat LR3 40mcg?

How does that sound?

Day one!

Started today...20/20mcg bilateral Shoulders. So far so good.

NattyNow · 11-15-2006, 11:49 PM

i was thinking of doing a somewhat large shot of mgf (say 200mcg) on sunday, working out mon and tues, wen off and then using igf pwo on thur and fri and maybe sat

i'd be training each bodypart about twice a week--once on the mgf and once on the igf

i've run a low dose of igf for 3 on, 4-off before and it worked well

has anyone tried anything similar yet?

UnicronSpawn · 11-16-2006, 06:31 AM

I tried 250mcgs peg-MGF once a wk w/ IGF 5 on 2 off @ about 20mcgs. Didnt use IGF on the day OF or the day AFTER the PEG-MGF shot. I got some ok gains w/ it, but I cant help but think Im not getting the most out of that combo. I just felt like there HAD to be a better more effective protocol possible. Because those gains I did make were along w/ Test, tren and GH. Id been on for awhile and my gains had been slowing down more and more despite adjustments in training and diet to get the ball rolling again. The PEG MGF/IGF helped me keep from completely hitting the wall, but I just think theres got to be a better way to cycle them. Im in PCT now and thinking of getting some more IGF and possibly more PEG MGF as well if I can afford it. Still takin the GH of course. Eating clean still(cept yesterday I caved in and had some fries w/ my chicken sandwich, cuz the sandwich