Growth Plates

Question, do HGH like igf-1 close off growth plates like aas do? Reason for asking is my little brother is getting 4 shots, i think if some type of HGH, to make him start peuberty i believe...but then i was wondering, how does it make u grow/start peuberty if it closes them off, maybe it doesnt? maybe he isnt taking a form of hgh like people use for muscle building.
 
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