Russianstar " EXPERIENCES WITH CJC-1295 DAC"

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    Russianstar " EXPERIENCES WITH CJC-1295 DAC"


    Written by Russianstar, This information is copyrited.

    Firstly lets explain what the peptide CJC-1295 DAC is.

    Molecular Formula: C152H252N44O42

    Molecular Weight: 3368.7

    Sequence of CJC1295 (modified) without DAC:

    H-Tyr-(D)Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-

    Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

    CJC-1295 is a GHRH (the 44-amino acid long version) with 15 aminos removed, thus a total of 29 amino acids, and bound to DAC it is also called Drug Affinity Complex, and CJC-1295 is often referred to as GHRH with Drug Affinity Complex, this essentialy lengthens its life span.
    This is how its life is lengthened.
    The modification of growth hormone releasing factor with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 2 create a much more stable peptide with the substitution at position 2 to prevent DPP-IV cleavage, position 8 to reduce asparagine rearrangement or amide hydrolysis to aspartic acid, position 15 to enhance bioactivity, and position 27 to prevent methionine oxidation. By utilising the Drug Affinity Complex technology to GRF, the peptide selectively binds to circulating albumin after subcutaneous administration, thus prolonging its half-life.
    As you may notice its basicly semorelin with 15 aminos removed. This was because semorelin degrades too rapidly to really make it a viable cost efficient option.
    So they bonded it with an attached 3-maleimidopropionic acid (MPA) unit, which results in binding to albumin after exogenous injection into blood plasma, and creates a far longer half life, this is the DAC, or druf affinity complex i made referance to earlier.
    Now it works by this action as its a GHRH, or growth hormone releasing hormone, In the healthy human body, large amounts of growth hormone are stored in the pituitary. The cells within the pituitary release growth hormone in response to signalling by GHRH (Growth Hormone Releasing Hormone) Then the peptide Ghrelin is (of which GHRPs - Growth Hormone Releasing Peptides - are mimetics), inhibited from releasing these stores by Somatostatin. GHRH and Ghrelin act on different populations of somatotropes (GH releasing cells). GHRP and Ghrelin increase the number of somatotropes releasing GH but not the amount released by each cell.
    GHRH affects both the number of secreting cells and - moreso - the amount they are actualy able to secrete. GHRH and Ghrelin are released in specific patterns that vary depending on what the person involved is doing, or has been doing post-exercise. Now CJC-1295 DAC has been proven to stimulate slow wave sleep, and this is the period of sleep when most of your bodys repairing work takes place on muscles and tissues etc.
    Now most people can and will make GH in their own pituitary gland, but not everyone can release it in the amounts needed, so from a medicinal point CJC-1295 DAC can be very beneficial.

    Now for its benefits to reach full potential, somatostatin needs to be inhibited because we have just seen it inhibits gh release, so by using a compound known as an Acetylcholineesterase inhibitor, now Acetylcholineesterase inhibits acetylcholine, and Acetylcholine inhibits somatostatin, so we want Acetylcholine in abundance, so by using an Acetylcholineesterase inhibitor, we allow acetylcholine to inhibit somatostatin, so increasing the amount of gh released when using CJC-1295DAC. Got it? Ok re read that last passage.
    The best of these Acetylcholineesterase inhibitors and there are lots like..
    Physostigmine
    Neostigmine
    Pyridostigmine
    Ambenonium
    Demarcarium
    Rivastigmine
    Phenanthrene derivatives
    Galantamine
    Piperidines
    Donepezil, also known as E2020
    Tacrine, also known as tetrahydroaminoacridine (THA')
    Edrophonium
    Huperzine A
    Ladostigil,
    Of the ones ive tried Huperzine A is the very best, and fairly cheap, now by adding ECGCs from green tea, as these ECGCs will transport the huperzine better so finding the receptor it needs the effects are even stronger on inhbiting the acetylcholineesterase.
    Otherwise a really good one i used recently was Horny goat weed, its the only one i know that actualy increases acetylcholine as it inhibits the enzyme acetylcholinesterase.
    Personaly i rate this as my favourite peptide, you get nearly a constant surge in gh especialy if you add in say huperzine A, you get all the benefits of hgh, improved body composition, anabolic effects, injury recovery, improved skin, the full works, and at a very good price, far cheaper than real gh.
    I have found that between 2000mcg -5000mcg a week has given me great results, increased bodymass over a 15 week period of nearly 9lbs, thats not weight gained, thats pure muscle and fat loss, You get all the same benefits of hgh, but you get them constantly, not just in one or 2 surges when you use the injections.
    Now i would use this in fat deposits as i noticed a reduction when i did so quite quickly, and directly into a muscle with this is quite painfull to say the least, so thats a no no from me.
    Expect to see results after just a couple of weeks, and the large amounts of igf-1 released will really add some muscle when incoorporated with a good diet and training regime.

    There are no sides ive seen with cjc just positive ones except for the amazingly strong head rush you get about 20 mins after the injection, this a tell tale sign as to wether or not you have the real thing.
    Remember the pulses are not as big as when you use GHRP-6, but rather its a continuous elevation of gh secretion peaking about 2 hours after the injection and staying elevated for 14 days. I use it 4 times a week in 500mcg doses and find this to be perfect for maintaining muscle when unable to train, say because of injury, and improving skin tone and health.
    3500mcg is a far more anabolic dose and muscle mass will be noticeably improved after 4 weeks, and the skin will start to take on that shredded ultra thin look that gh users get before competitions.
    All the benefits of real GH, less injections, less sides, a lot less money.... need i say more.
    Only one thing i should make mntion of, is that according to dat, it can cause gh bleeding, possibly causing reduced gh sensitivity over time.

    I hope you have found this information helpfull, i feel its one of the very best peptides if not the best.

    Russianstars peptide rating 9/10

    Kind regards RS
    Gause institute member

    Need2slin designer.Product designer/ **** admin.

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    Thanks for this write up...

    I have been looking into this over the past 12 months for some help with disk issues. Though, I have read where some people have not had much success using it for torn disk.
    ---The internet is the father of the electronic lynch-mob---
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    Quote Originally Posted by hardknock View Post
    Thanks for this write up...

    I have been looking into this over the past 12 months for some help with disk issues. Though, I have read where some people have not had much success using it for torn disk.
    I would use a transdermal lovastatin, or igf-lr3 probably.

    I was reading a study the other day about igf-lr3 caused bone regrowth, lovastatin in a transdermal is very effective too, you can make it yourself.

    I read something else too, il look it up and post it here if i can find it.

    RS
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    Great info on cjc. I've been looking into starting a cycle but I'm not sure of a reputable company to buy good peps from. Can u help ?
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    Quote Originally Posted by rocko1 View Post
    Great info on cjc. I've been looking into starting a cycle but I'm not sure of a reputable company to buy good peps from. Can u help ?
    I think the best thing to do is come to **********************, then pm me there im russianstar on all forums, il help you out anyway i can bro. rs
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    Thanks I'll do that I appreciate it
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    Quote Originally Posted by rocko1 View Post
    Thanks I'll do that I appreciate it
    Thanks man, read your pm's i hope ive helped.

    RS
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    Need2slin designer.Product designer/ **** admin.
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    Quote Originally Posted by russianstar View Post
    I would use a transdermal lovastatin, or igf-lr3 probably.

    I was reading a study the other day about igf-lr3 caused bone regrowth, lovastatin in a transdermal is very effective too, you can make it yourself.

    I read something else too, il look it up and post it here if i can find it.

    RS
    Thanks man!

    BTW: I looked back on **** site the other day and spotted you in my request list. My bad, I have so many sites that i am on now i totally forgot I was a member there.
    ---The internet is the father of the electronic lynch-mob---
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    I saw your other thread about GHRP-6 and you noted a pec tear. I am currently in recovery for tearing two heads of my pec off the humerous as well. I just finished running IGF-1 following the surgery and thinking of going into GHRP-6 and CJC-1295 dac.

    With your injury you recomended pinning in the muscle close to the tear which is what I have done with the IGF. I'm just not clear on if I should do the same with the CJC or just go sub Q. pinning IM would be easier since I could just mix with the GHRP for one shot 3x/day.

    Thanks for your input.
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    any reliable board sponsors that one of you can recommend in a PM?
    "The Iron never lies to you."~Henry Rollins
    "People have to get away from the dogma that it's all free weights or all machines. They can have sex. You can do both."~Dave Tate
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    since the gh levels stay elevated for 14 days would it be necessary to inject every week?
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    RS,

    I did some reading in this thread:

    http://www.professionalmuscle.com/fo...ic-guides.html

    It seems to suggest that 100mcg/day is the "sweet spot" dose, and stacking with a GHRP is synergistic.

    Thoughts on this? What doses of Huper/EGCG were you using?
    Paging Dr. Banner. . .
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    my goal: build some muscle while i lose fat.
    question: you said you pinned 3500mcgs 4x week. do you recomended me doing the same thing for my frist time? and you ment 3500mcgs in 1 shot in the stomach fat lets say right ?
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    Quote Originally Posted by GLHF View Post
    my goal: build some muscle while i lose fat.
    question: you said you pinned 3500mcgs 4x week. do you recomended me doing the same thing for my frist time? and you ment 3500mcgs in 1 shot in the stomach fat lets say right ?
    i've read the bible on this, and no more than 2.1 mgs per week, for 6-12 wks. you risk damaging your pituitary and growing your organs at that dose. there's just no good reason for that, IMO. then again, i am not a bodybuilder, nor do i want to look like one, which i say without any judgment once so ever. good luck.
    "The Iron never lies to you."~Henry Rollins
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    Hey man I have a few questions about the CJC1295 DAC Gh stacked with Huperzine A...can I run Forma Stanzol with it as well? And if so how long would I run this cycle for and the doses used? One more thing, would i have to run a PCT like the one you threaded about earlier after this cycle?? Thanks bro
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    Quote Originally Posted by OnTheRoadTo View Post
    RS,

    I did some reading in this thread:
    prof musc site

    It seems to suggest that 100mcg/day is the "sweet spot" dose, and stacking with a GHRP is synergistic.

    Thoughts on this? What doses of Huper/EGCG were you using?
    from that link
    This Article is now out of date. CJC-1295 is counterproductive should not be used because of its effect on GH "bleed".

    it also mentioned that modified GRF(1-29) together with a modulator GHRP-2 should be used
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    Quote Originally Posted by kadox View Post
    from that link
    This Article is now out of date. CJC-1295 is counterproductive should not be used because of its effect on GH "bleed".

    it also mentioned that modified GRF(1-29) together with a modulator GHRP-2 should be used
    oh yeah, the bleed. same reason that hCG shouldn't be used ... because your bleeding test all day, every day. LOL. seriously, read up on what the "bleed" is ... an increase of trough levels, from which the pulses occur.
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    I'm fairly new to CJC-1295 and Ipamorellin but have done my research I was wondering if you could review my cycle and give me any advice on their use?

    I currently am taking CJC-1295 without DAC ( I realize now I maybe should have ordered with DAC?)
    And Ipamorellin

    I currently inject 100mcg of each 5 times per day
    1 upon waking
    1 after training
    2 more throughout the day
    1 Dose before bed

    I am also currently taking Horny Goat weed but will aquire Huperzine A and EGCG in short order

    I have been Dosing some Intramuscularily and some Subcutaneously just to avoid feeling like a pin cushion.

    I can also add that my post workout Dose is double to gain increased effect.

    Diet Training and Cardio are very consistent and daily.

    I also have Methyl-1-Test pills 10 mg and 4-AD 250mg
    which I plan to start soon I was just hoping to gain some new muscle fiber satellite cells before starting that regimen added to the peptides.

    If you could give me some guidance or improvements to my regimen I would be most gratefull

    Thank You
  

  
 

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