If igf acts in a similar way to HGh (i.e. hyperplasia) why would you need to cycle it, as suggested by bobo? After all, users of HGh can usually take it for months with better results than they would get from a 5-week cycle (especially for fat loss). Is there a significant feedback mechanism that would down-regulate the body's own synthesis of IGF and take time to recover from IGF usage? From what I'm reading on this forum, the post-cycle effects of IGF only seem to be psychological anyways (withdrawal symptoms).