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Benzodiazapines block igf-1?

  1.  01-22-2010  06:44 AM
    Registered User hulky10's Avatar
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    Benzodiazapines block igf-1?


    I take kilonopin for anxiety and just read a study the mentioned it has an effect on igf-1 secretion. And since I'm taking igf-1, this wouldn't be good.... Any insight appreciated.



  2.  01-23-2010  08:22 PM
    Registered User saemc's Avatar
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    IDK?.I hope not,i take an occassional benzo 4 sleep and haven't noticed any negative effects or lack there of,but i don't take regularly/daily,so maybe it possibly could??..I need more info on this!!

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  3.  01-24-2010  09:41 AM
    Registered User hulky10's Avatar
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    Bump

  4.  01-25-2010  08:24 PM
    Registered User CrazyChemist's Avatar
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    Originally Posted by hulky10 View Post
    I take kilonopin for anxiety and just read a study the mentioned it has an effect on igf-1 secretion. And since I'm taking igf-1, this wouldn't be good.... Any insight appreciated.
    Correct me if I'm wrong but if you are on IGF-1 then your natural secretion of IGF-1 is negligible. Isn't the body's natural level <1mcg? So you are already taking at least 40i.u.. Why worry about the benzos effect on your natural secretion?
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  5.  07-11-2010  12:23 AM
    Registered User Evan Bageris's Avatar
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    There are no known contraindications regarding Benzo's taken concurrently with IGF-1.
    Benzo's don't block Igf-1 nor the other way around. BTW, Klonopin isn't classified as a benzo, although it certainly fits the bill structurally and is often prescribed for the same symptoms as Xanax, Ativan, Valium etc. This has led many to believe it is not addictive in the same way as the above mentioned, but that is pure fallacy. The rehabs across America are filled with people who need long term care to D/C Klonopin. It still won't affect your exo or endo IGF.

  6.  07-11-2010  12:28 AM
    Registered User GnastyMcNasty's Avatar
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    Originally Posted by Evan Bageris View Post
    There are no known contraindications regarding Benzo's taken concurrently with IGF-1.
    Benzo's don't block Igf-1 nor the other way around. BTW, Klonopin isn't classified as a benzo, although it certainly fits the bill structurally and is often prescribed for the same symptoms as Xanax, Ativan, Valium etc. This has led many to believe it is not addictive in the same way as the above mentioned, but that is pure fallacy. The rehabs across America are filled with people who need long term care to D/C Klonopin. It still won't affect your exo or endo IGF.
    Klonopin (clonazepam) most certainly IS a benzodiazepine, and is just as addictive as the rest of them. What makes it different from one like xanax is its long half-life (6 days) as opposed to xanax's which is like 6 hours or something. So klonopin's addictive potential in terms of withdrawal is less because it does not cause as large a rebound. This is why it is often used to "ween" off of other fast-acting, harsher benzos like xanax, ativan, valium, etc. But it is a benzodiazepine by all accounts.

  7.  07-11-2010  12:34 AM
    Banned deadaim's Avatar
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    Klonopin has the largest half-life out of the big range of benzos, which does make it useful to wean people of shorter acting medicines like valium or xanax

  8.  07-11-2010  03:28 PM
    Registered User criticalbench's Avatar
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    This is interesting, I have to look into this. Good post bro.
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  9.  07-13-2010  03:31 AM
    Registered User slow's Avatar
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    I am curious about the first comment:

    "kilonopin for anxiety and just read a study the mentioned it has an effect on igf-1 secretion"

    Where did you read this?


    Btw: Valium and its metabolites have a long half life.

  10.  07-14-2010  10:49 AM
    Registered User GrowthMan1's Avatar
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    Originally Posted by hulky10 View Post
    I take kilonopin for anxiety and just read a study the mentioned it has an effect on igf-1 secretion. And since I'm taking igf-1, this wouldn't be good.... Any insight appreciated.

    Can we see the study?

  11.  07-14-2010  11:00 AM
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    Valium may have a long half-life but its acute half-life, or the length of time where its effects can really be felt is only about 6-8 hours. Klonopin is more in the 12-14 range.

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