to quote one of the articles posted by bobo
100mcg PER kilogram of bodyweight TWICE a day to prevent protein breakdown? everyone suggests taking 20-40mcg a day (regardless of size)...... why?They divided the volunteers into three groups who got one of the following: IGF-1 alone, IGF-1 plus prednisone, and prednisone alone. The study found that IGF-1 at 100 micrograms per kilogram of body weight given twice daily enhanced the body's protein metabolism in the same way as growth hormone. Like growth hormone, it markedly decreased the protein breakdown in the volunteers who were taking prednisone.