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    Quote Originally Posted by mr.cooper69 View Post
    My guesses: creatine orotate, some form of ALA, beta-alanine, ALCAR, and something novel like Pyrroloquinoline quinone.
    Quote Originally Posted by dtrain13 View Post
    I was thinking BA, ALCAR and PQQ as well.
    I like those guesses.

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    Quote Originally Posted by mr.cooper69 View Post
    My guesses: creatine orotate, some form of ALA, beta-alanine, ALCAR, and something novel like Pyrroloquinoline quinone.
    Nope, nope, nope, nope annnd nope.

    I'll say this, though, we were really pursuing PQQ as an additive, but that sh't is expensive... and I mean expensive.

    We want this to retail for under $30 and that stuff, awesome as it is, would've pushed this into the 40s or even 50s.
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    Quote Originally Posted by Smitty77 View Post

    Nope, nope, nope, nope annnd nope.

    I'll say this, though, we were really pursuing PQQ as an additive, but that sh't is expensive... and I mean expensive.

    We want this to retail for under $30 and that stuff, awesome as it is, would've pushed this into the 40s or even 50s.
    It's insane how much some of these ingredients can run.
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    Quote Originally Posted by Tyler44 View Post
    It's insane how much some of these ingredients can run.
    Patrick Arnold once mentioned (and I paraphrase) that he'd have a million great ideas made into great products if it weren't for ingredient cost.
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    Believe me, I can definitely appreciate that creating a good formula is only like 5% of actually making it happen. I'm glad you didn't go with PQQ btw. It has a TON of therapeutic research but I was really on the fence about whether or not it would actually help healthy athletes. Its downstream effects are also quite varied and would be difficult to manipulate and isolate (i.e. concomitant activation of both oncogenes and tumor suppressors).
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    The above is my own opinion and does not reflect the opinion of PES
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    Is the flavoring system almost complete? I know it is tough to release the label before that is complete.
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    hope so. I will be receiving the latest tomorrow. Might not taste the best because of some of the ingredients are hard to flavor but if its ok well release. Ill be able to report tomorrow hopefully.
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    Quote Originally Posted by GENOMYX View Post
    hope so. I will be receiving the latest tomorrow. Might not taste the best because of some of the ingredients are hard to flavor but if its ok well release. Ill be able to report tomorrow hopefully.
    If it is a nice profile, I don't people will mind. I know flavoring does help sell products, but Clout sells pretty well even though it has a funky taste.
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    Quote Originally Posted by GENOMYX View Post
    hope so. I will be receiving the latest tomorrow. Might not taste the best because of some of the ingredients are hard to flavor but if its ok well release. Ill be able to report tomorrow hopefully.
    Toss it into Protocol = Profit?

    I know I personally don't care too much (had plenty of Clout and Ultima before) but understand the masses tend to complain about such things.
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    Quote Originally Posted by mr.cooper69 View Post
    Believe me, I can definitely appreciate that creating a good formula is only like 5% of actually making it happen. I'm glad you didn't go with PQQ btw. It has a TON of therapeutic research but I was really on the fence about whether or not it would actually help healthy athletes. Its downstream effects are also quite varied and would be difficult to manipulate and isolate (i.e. concomitant activation of both oncogenes and tumor suppressors).
    How does PQQ differ from CoQ10?

    I've read that unlike CoQ10, which is located in the mitochondria's electron transport chain, PQQ is located in the cytoplasm. Is that correct?

    Can you shed a bit of info on PQQ?
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    Quote Originally Posted by Smitty77 View Post
    Nope, nope, nope, nope annnd nope.
    Damn. CoQ10 then. LOL
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    Quote Originally Posted by mr.cooper69 View Post
    Believe me, I can definitely appreciate that creating a good formula is only like 5% of actually making it happen. I'm glad you didn't go with PQQ btw. It has a TON of therapeutic research but I was really on the fence about whether or not it would actually help healthy athletes. Its downstream effects are also quite varied and would be difficult to manipulate and isolate (i.e. concomitant activation of both oncogenes and tumor suppressors).
    We were really focused on mitochrondrial/cellular health with this one, some favorable information related to that, of course. However, in our search for a replacement, we honed in on something that functions in that capacity, and presents with a multitude of other benefits.

    We're fans of Ayurvedic herbs, so, you know how it goes.
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    Quote Originally Posted by Smitty77 View Post
    We were really focused on mitochrondrial/cellular health with this one, some favorable information related to that, of course. However, in our search for a replacement, we honed in on something that functions in that capacity, and presents with a multitude of other benefits.

    We're fans of Ayurvedic herbs, so, you know how it goes.
    Would most be familiar with the ingredient panel? Or, have do you guys have some novel inclusions?
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    Quote Originally Posted by domore View Post
    Would most be familiar with the ingredient panel? Or, have do you guys have some novel inclusions?
    It's 4 ingredients... one of which can be considered a novel inclusion.
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    Quote Originally Posted by Smitty77 View Post
    It's 4 ingredients... one of which can be considered a novel inclusion.
    Thanks, Smitty.

    If it suits my fancy, I'll add it to my Protocol stash.
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    Quote Originally Posted by Smitty77 View Post
    It's 4 ingredients... one of which can be considered a novel inclusion.
    I really like the simple approach you guys take with formulations in terms of amount ingredients. Short and to the point so to speak.
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    Quote Originally Posted by domore View Post
    How does PQQ differ from CoQ10?

    I've read that unlike CoQ10, which is located in the mitochondria's electron transport chain, PQQ is located in the cytoplasm. Is that correct?

    Can you shed a bit of info on PQQ?
    PQQ is ultimately nothing like CoQ10 save for its extremely high oxidoreductase potential. It is more of a signaling molecule and cofactor than a medium for electron transport to complex III. Whereas Coq10 seems to optimize ETC-dependent mitochondrial function on a mitochondrion per mitochondrion basis, PQQ simply increases the number of mitochondria (via PGC-1alpha). Stimulating PGC-1alpha is actually being investigated in the treatment of mitochondrial diseases (e.g. Subacute Necrotizing Encephalomyelopathy), as researchers figure that if the baseline mitochondrial function is far below normal (accounting for heterogeneity), increasing total mitochondrial content of mt-dependent cells (e.g. brain and muscle' hence, encephalomyelopathies) may ameliorate symptoms. So far though, the research has been unsuccessful, so I wouldn't get my hopes too hung up on PQQ. Not to mention that due to homology between mitochondria and prokaryotes, PQQ can stimulate bacterial infection if taken systemically.
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
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    Quote Originally Posted by mr.cooper69 View Post
    PQQ is ultimately nothing like CoQ10 save for its extremely high oxidoreductase potential. It is more of a signaling molecule and cofactor than a medium for electron transport to complex III. Whereas Coq10 seems to optimize ETC-dependent mitochondrial function on a mitochondrion per mitochondrion basis, PQQ simply increases the number of mitochondria (via PGC-1alpha). Stimulating PGC-1alpha is actually being investigated in the treatment of mitochondrial diseases (e.g. Subacute Necrotizing Encephalomyelopathy), as researchers figure that if the baseline mitochondrial function is far below normal (accounting for heterogeneity), increasing total mitochondrial content of mt-dependent cells (e.g. brain and muscle' hence, encephalomyelopathies) may ameliorate symptoms. So far though, the research has been unsuccessful, so I wouldn't get my hopes too hung up on PQQ. Not to mention that due to homology between mitochondria and prokaryotes, PQQ can stimulate bacterial infection if taken systemically.
    Would activating PCG-1a be beneficial for infants who are looking for improved mitochondrial biogenesis? I did read that small amounts (really small) of PQQ are found in breast milk.

    On a side note, is this protein also related to controlling blood pressure?
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    Quote Originally Posted by Smitty77 View Post
    It's 4 ingredients... one of which can be considered a novel inclusion.
    So, four ingredients with one (at least) being a form of creatine. May I ask how many of the three are Ayurvedic herbs? I heard they were causing the watermelon-lime flavor to be thrown off.

    And...Project Blue?
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    CREignite


    There will be some form of creatine in it.
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    Quote Originally Posted by MM11 View Post
    There will be some form of creatine in it.
    Haha, thanks
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    This looks somewhat interesting. I already have creatine though and 1 tub lasts me a year at less than $20.
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    Right now I'm using di creatine malate. Costs me around 3$ a month. Mono destroys me.
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    Quote Originally Posted by MM11 View Post
    Right now I'm using di creatine malate. Costs me around 3$ a month. Mono destroys me.
    Well, since Smitty said it isn't creatine orotate, I hope it is MCC or creatine nitrate.
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    Name:  547556_10151309230239016_1953765056_n.jpg
Views: 178
Size:  11.1 KB

    Can I have this, please?
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    Quote Originally Posted by domore View Post
    Name:  547556_10151309230239016_1953765056_n.jpg
Views: 178
Size:  11.1 KB

    Can I have this, please?
    Me too?
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    Quote Originally Posted by domore View Post
    Name:  547556_10151309230239016_1953765056_n.jpg
Views: 178
Size:  11.1 KB

    Can I have this, please?
    bahahaha loved it mixed with ORIGIN, and PROTOCOL. endurance was off the chain
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    Quote Originally Posted by vicesoldier View Post
    bahahaha loved it mixed with ORIGIN, and PROTOCOL. endurance was off the chain


    I need some to stack with Protocol!
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    It will come. Soon
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    Saw the flavor was finally approved. Bring on the Watermelon.
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    Quote Originally Posted by bolt10 View Post
    Saw the flavor was finally approved. Bring on the Watermelon.
    I didn't see that! I'm in for some watermelon!
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    Quote Originally Posted by domore View Post
    I didn't see that! I'm in for some watermelon!
    Once we have a set date for release we will post up the profile and ETA to retailers
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    Quote Originally Posted by vicesoldier View Post
    Once we have a set date for release we will post up the profile and ETA to retailers
    My goodness, I have been waiting to the profile for a while.
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    Updates?
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    Flavor has been completed and the product has already headed into production. Flavor will be watermelon and Fruit punch will be released by summer. We had a sample of both recently and they were both perfect.

    Make sure to follow us on Facebook, twitter or instigram. I believe today is our last day on the AM.
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    Quote Originally Posted by GENOMYX View Post
    Flavor has been completed and the product has already headed into production. Flavor will be watermelon and Fruit punch will be released by summer. We had a sample of both recently and they were both perfect.

    Make sure to follow us on Facebook, twitter or instigram. I believe today is our last day on the AM.
    Ahh! Last day?! You guys got to do what you have to do.

    I'll be sure to grab some.
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    Thanks brother our relationship with Nutraplanet is stronger than ever so expect some sick deals. Maybe even exclusive Ill still be around and so will the reps. Feel free to pm use or email if you have any questions.
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    Quote Originally Posted by GENOMYX View Post
    Thanks brother our relationship with Nutraplanet is stronger than ever so expect some sick deals. Maybe even exclusive Ill still be around and so will the reps. Feel free to pm use or email if you have any questions.
    Good deal! I'll be sure to hit you guys up, I still have a bunch of VB12 strips. You guys will continue to put great products out.
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    Sad to see you go but will still be keep following for future updates.
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    Thanks guys. If you haven't already sign up on our site for newsletters. Ill get those going this week for those not really using social media
  

  
 

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