Ugh, I hate fast food, I burp it up for the entire day if I eat any. All you.
Btw hows your progress coming for the contest?
Well, I'm kinda bulking right now, and seeing mostly strength increases, and a little size. I got a little bit of a late start. Haven't added fat so far, which is always a plus for me!
How bout you?
My understanding has always been that 17a alkylation helped the steroid resist breakdown in the liver, not that it improved absorption from the GI system.
I'm not saying you're wrong, I'm just saying that I've never heard that. Can you please provide references for this?
I don't have a specific reference at the moment in regards to absorption & 17aa steroids. I do have links to the digestive system.
The Digestive System - Some good links off of this page.
Also -
Digestive System
Think of the liver as the gatekeeper of how your food is digested and used. It regulates fuel management (usage of protein, carbs, & fat) and metabolism, and nitrogen & waste excretion. I don't know what role the liver plays in the small amount of foods digested in the stomach (sugars, salt, water, etc.), but I believe that all food intake eventually meets up with the liver in one way or another. The 17aa prevents the liver from breaking the steroid down for excreting, which in turn would keep it in tact for absorption. The liver sees an oral steroid as a "foreign" object with no nutritional value, and would do it's best to excrete it rather than absorb it. So if the liver doesn't rid/excrete the 17aa steroid, it can then still be absorbed through the intestines. This is why 17aa steroids are considered "orally active," hence taking it with fat isn't needed.
The idea of taking a non-17aa oral steroid with fat works by the same concept, but not the same mechanism. The main goal is to avoid breakdown & excretion by the liver. Once the steroid is "disolved" into the fat, it will then be mostly digested via liver bile in the small intestines, rather than excreted. See where I'm going?
Maybe someone such as Bobo with a good understanding of Nutrition can elaborate or explain this better.
Sorry to hijack your thread, Nobady, but hopefully this helps with one of your original questions.