For those of you who take Serzone for depression...

  1. For those of you who take Serzone for depression...

    I do though I have been weaning my self off slowly for awhile now. Just thought some out there would like to know that its potential to do liver damage is once again in the spot light.

    Consider natural alternatives to anti-depressants

    By Dr. Phil Maffetone

    Recent news linking liver failure to use of a popular anti-depressant drug once again brings into focus the question of the effectiveness of these drugs versus the side-effects and risks that accompany them.

    According to an Associated Press report, the anti-depressant Serzone has been pulled from the market in Europe after 11 deaths due to liver failure were linked to the drug. Now consumer advocacy groups are urging its ban in the United States.

    Anti-depressant drugs such as Serzone, aimed at regulating neurotransmitters in the brain, are the standard treatment for depression. Although these are among the most heavily prescribed drugs in the world, many patients do not respond to them for various reasons. And the side-effects are numerous.

    Before resorting to radical drug therapy for depression, some conservative lifestyle, diet and nutrition measures should be considered.

    For instance, the balance of neurotransmitters in the brain has a direct link to diet. Many people can benefit by finding the proper balance of macronutrients -- carbohydrate, protein and fat -- that contributes to proper balance of neurotransmitters.

    In addition, depression has been linked to inadequate levels of omega-3 fats in the brain, and also to high blood homocysteine levels. Increasing consumption of foods high in omega-3 fat can increase levels in the brain, and consuming foods that are high in folate, such as green leafy vegetables, can reduce homocysteine. In fact, research shows many people who do not respond favorably to anti-depressant medication actually see improvement when they increase folate consumption.

    Other lifestyle measures can also help people with depression. For instance, easy aerobic exercise has been found to improve depression. Also, certain stress reduction methods, such as making a stress list, can help improve systems.

    If these diet, nutrition and lifestyle measures are not enough, there's also herbal relief. Several clinical trials have shown St. John's Wort to be as effective as anti-depressant drugs in treating mild to moderate depression with fewer and less-dangerous side effects.

    In short, before taking the risk of anti-depressant drugs, consider the alternatives. More detailed information about natural alternatives to anti-depressant medications mentioned in this article, are contained in my book, In Fitness and In Health.

  2. great, i was on serzone for a long while, good to know this now

  3. Ask your doctor for an alternative if need be. There are many other anti-depressants such as Effexor and Wellbutrin. If you want to look up what side effects there are just go to webmd and look up that medicine.

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