MikeBU
Developing Meathead
- Awards
- 0
So this kid with the mutated myostatin gene got me thinking.
There are currently anti-bodies available for myostatin that bind to the protein for western blots/ELISA's etc. I know that if you were to inject anti-bodies into a human the anti-body would dissappear in a matter of hours (if that) and would be useless since you would need to inject yourself all day. The company I work for (and I am sure other companies have similar things) has a modified constant region which extends the half-life of an anti-body for up to 120 hours! You can see where I am going with this. So my question is, would an anti-Myostatin Ab inhibit myostatin in a human?
There are currently anti-bodies available for myostatin that bind to the protein for western blots/ELISA's etc. I know that if you were to inject anti-bodies into a human the anti-body would dissappear in a matter of hours (if that) and would be useless since you would need to inject yourself all day. The company I work for (and I am sure other companies have similar things) has a modified constant region which extends the half-life of an anti-body for up to 120 hours! You can see where I am going with this. So my question is, would an anti-Myostatin Ab inhibit myostatin in a human?
