I havent done herione, any lsd or acids, pcp, peyote, ketamine, or meth.
Other than that, unless I'm forgetting any extreme ones, I've done the rest.
Shrooms is very fun. Closest thing to a "religious" experience, aside from acid, that I think you can get. Didnt really change the way I see things though. Deep thoughts but nothing unachievable w/o it.
When my little bro was fourteen one of his classmates took acid. He said he thought he could understand the fourth demension..though couldnt explain that to us. But what really grabbed me was that while he was on it he concluded that if he didnt move, time stopped. While this isnt true, the idea behind it is. If you could halt all motion in the universe so that nothing moved relative to anything, time would stop. That concept was pretty advanced for a fourteen year old mind.