Obama declares swine flu a national emergency

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  1. Quote Originally Posted by Trauma1 View Post
    The success rate is not necessarily poor. It largely depends on the strains that are being reported, and which strains were comprised in that years vaccination efforts. The scientists make educated guesses about the strains for the year. The thing is, influenza mutates on a regular basis, and is the reason why we continue to have outbreaks every year without a universal vaccination. They are getting closer though at a universal effort. There are certain aspects about the influenza virus that remain consistant with each strain, and they're working on being able to get the body to recognize that unique aspect, and then form adaptive immunity as a result.
    Exactly, and this is an unfortunate aspect people are disinclined to research and understand - that is, that the genetic similarities between the strains of H1N1 subtype of the Influenza A Virus impart the vaccines modified for each strain an a priori safety, efficacy and applicability. Despite it being swine origin, and as you know, the point mutations in SIV's DNA have been reported to be a several dozen amino sequences away from the H1N1 strain responsible for both the majority of seasonal influenza infections, as well as the so-called, "Spanish Flu". And as a result, all this rhetoric and nonsense about it being "unfounded," and "compromising" can hardly be characterized as scientifically valid. As far as I know, the most recent modifications to the Influenza A vaccine have been specifically to combat RNA synthesis and replication by attacking the novel form of RNA polymerase which H1N1 uses to synthesize itself. By all means, a modification which should not turn this [...fairly...] effective vaccine into a people-killer!


  2. Quote Originally Posted by Jayhawkk View Post
    Everyone I know who has reported to the clinic with the flu has gone home with a 'probably' h1n1 without official confirmation. Apparently only serious situations and deaths get the actual test to make sure.
    That's because anyone testing positive for influenza subtype A (which H1N1 is derived) is automatically assumed to be positive for H1N1 (which requires further testing). In all reality, the flu is the flu. Most symptoms are self-limiting, and the treatment is exactly the same: Rest, Fluids, and more Rest. Influenza is deadly to certain populations; especially in those that are immunocompromised (i.e., HIV/AIDS, Cancer, Pregnant women (especially during the 3rd trimester), Autoimmune Diseases, and the very young and very old.) Diabetics are also at increased risk for complications.

    Antivirals can be initiated (Relenza and Tamiflu) to help reduce symptom severity and duration, but they HAVE to be started within 24-48 hours of symptom onset to be any advantage at all.

    Evolutionary Muse - Inspire to Evolve
    Legendary

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  3. Quote Originally Posted by YajV24 View Post
    Thousands, or Millions of people missing work during an economic recession would be disastrous.

    But yeah...You're right. Its all a big scam. The vaccine is actually a serum that will induce acceptance of our new socialist philosophies.

    We're tracking your IP now and will be murdering you shortly. See you soon.
    Hahaha

  4. Roger that trauma! Always enjoy your reality input to these subjects!

  5. Quote Originally Posted by Mulletsoldier View Post
    Exactly, and this is an unfortunate aspect people are disinclined to research and understand - that is, that the genetic similarities between the strains of H1N1 subtype of the Influenza A Virus impart the vaccines modified for each strain an a priori safety, efficacy and applicability. Despite it being swine origin, and as you know, the point mutations in SIV's DNA have been reported to be a several dozen amino sequences away from the H1N1 strain responsible for both the majority of seasonal influenza infections, as well as the so-called, "Spanish Flu". And as a result, all this rhetoric and nonsense about it being "unfounded," and "compromising" can hardly be characterized as scientifically valid. As far as I know, the most recent modifications to the Influenza A vaccine have been specifically to combat RNA synthesis and replication by attacking the novel form of RNA polymerase which H1N1 uses to synthesize itself. By all means, a modification which should not turn this [...fairly...] effective vaccine into a people-killer!
    My sentiments as well, K.

    Many of the pharmacological antivirals look to disrupt RNA synthesis of the virus inhibiting its replication ability; while others are designed to inhibit specific factors (mainly proteins) that the virus needs to survive. Tamiflu for example looks to inhibit the virus from being able to liberate itself from the host cell and spread. Tamiflu targets a protein called neuraminidase that lives on the flu virus cells. This protein helps the flu virus break through the cell walls so it can move on to other cells and replicate itself. Tamiflu inhibits the neuraminidase protein, so that the virus can't leave the cell to infect other cells. Eventually, the virus dies.

    Most vaccines look to introduce the specific viral protein coat antigen that the humoral immune system will recognize, form antibodies against, and eventually develop adaptive immunity as a result. I had a really good article on the H1N1 vaccine, but I don't know where I stored it on my computer.

    The 1918 "Spanish Influenza" pandemic was very interesting; especially in that it was very deadly to the young and healthy with a robust immune system. That viral variant played off the strong immune response, and caused the massive release of the inflammatory mediator, cytokine. It was termed a "cytokine storm"; which lead to massive respiratory complications, and very often death. Many of those people also died from secondary bacterial opportunistic infections though (primarily pneumonia); as is the potential case with all influenza illness.

    I started a Vitamin D thread here recently. They're finding that Vitamin D not only is heavily involved in the upregulation of endogenous antimicrobial peptides (mainly the cathelicidins) which help prevent incidence of infection, but also blunts the over-response of the immune system inflammatory mediators; esentially not making the immune system better, just much smarter. These findings are huge in terms of Influenza/disease prevention and treatment.

    Evolutionary Muse - Inspire to Evolve
    Legendary

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  6. Quote Originally Posted by bioman View Post
    You need to maybe pay more attention to what's going on. We've had 47 deaths in AZ related to H1N1. Nearly everyone I know has had it..especially my friends associated with health care. It's active in my daughter's daycare.
    What part of AZ are you in? There hasn't been a single confirmed case on my university's campus. I'm sure if I go out of my way to look for cases I could find them but I figure if it was a big enough problem where I live I would a)be hearing of many more cases b)know someone or even know someone's cousin's sister's aunt's boyfriend's hair stylist who has it but I haven't even experienced that. Just wondering if you live in the scottsdale/paradise valley area or glendale(where my campus is)?
    My mother also is a nurse in a retirement/assisted living home(in Scottsdale) and there have been no incidents there, thankfully.
    The distinction between the symptoms of H1N1 and regular flu seem unclear as well.
    And you say nearly everyone you know has had it...Since you didn't say otherwise I'm assuming they are over it and fine now? So I don't see a need to panic. Obviously the elderly and young should be more careful and those that work in healthcare but I am neither and left my job at Banner months ago. I already worry about enough crap as it is, I don't see any benefit in getting myself worked up here. I'll continue to wash my hands frequently, eat well, exercise, take vitamins, etc etc and if I get it I get it...
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