Unless I missed something, I've always heard that standing bicep curls are better for mass building, and preacher is isolation and more for defining the muscle. If you want bigger biceps do standing barbell curls. That is more effective out of the 2. Bigger arms come from chin ups, rows, deadlifts, and other mass building exercises. BB curls just target the bicep and aid in mass growing specifically to that area. I'm not sure on the rep amount. I usually do 10, 8, 6. Increasing the weight every time.