What do YOU want to see next from EBF
- 08-26-2012, 06:51 PM
- 08-26-2012, 09:26 PM
Originally Posted by domore
Will report with studies when I confirm what I want to use.
08-26-2012, 10:24 PM
08-27-2012, 10:10 AM
08-27-2012, 10:18 AM
However, i do have a question regarding Osthole's ability to glucose uptake through AMPk in skeletal muscles and it being used as a muscle-building product.
So, AMPk activation inhibits glycogen storage and increases glucose uptake. Therefore, it seems to help improve insulin sensitivity and in skeletal muscles AMPk activation increases fatty acid oxidation.
AMPk is "turned on" when the cellular energy state of the cells drops. From what I have read, AMPk turns off energetically costly processes like protein synthesis and turns on energy producing processes like glucose and fat oxidation.
Now here lies my question.
Can leucine's activation of mTOR override AMPk's suppression of mTOR during exercise and continue to let growth occur?
This isn't my field, so if I am amiss please correct me.
08-27-2012, 01:46 PM
08-28-2012, 08:50 PM
Did some more research. It seems likely that you are going to need extremely large doses of Osthole due to it being a hydrophobic/poorly soluble compound with limited bio-availability.
08-28-2012, 09:44 PM
What do you consider extreme.Originally Posted by domore
There will be an ingredient to aid availability
08-29-2012, 05:46 AM
08-29-2012, 11:14 AM
Read that too, but is AR stimulation the only mechanism it works through?
EBF, you said you had been taking this. I've read multiple times that osthole is A PDE-5 inhibitor. Any effect in the erection department?
Also read about stomach issues and feeling sick. Anything here?
08-29-2012, 12:01 PM
At 400 mg per day it's goodOriginally Posted by Ape McGrapes
I'm using 1800-2000 mg osthole per day. That's erections fine if stimulation is there otherwise I am always busy do don't notice much. Strength n leanest is pronounced at the dose I'm using
08-29-2012, 12:03 PM
08-29-2012, 12:05 PM
08-29-2012, 12:10 PM
Yes. I haven't gotten a chance to get back to you as of yetOriginally Posted by MAxximal
No cramps or headaches. When increasing dose to 600mg the first 2x I did get light headed. Subsided after that though
08-29-2012, 12:38 PM
Muscle builder sounds interesting. Can't wait to see what you come up with!
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PM me with any questions!
08-29-2012, 12:42 PM
08-29-2012, 01:05 PM
08-29-2012, 02:30 PM
I have stopped aav2 to test the osthole.Originally Posted by Ape McGrapes
I would take about 14mg capsaicinoids a day. When I was using it.
08-29-2012, 05:06 PM
Fat just meltin offOriginally Posted by EBF Inc
...::: Olympus Labs Athlete & Representative :::...Crossfit - DEMIGOD -
09-02-2012, 03:00 PM
09-02-2012, 03:04 PM
Not to bad. I think the dose of osthole I'm using is way to high. Throat issues since like 2 days after dosing at 1800-2000 mg. I had same effects and no sides at 800-1200mg.Originally Posted by domore
Libido is there. Wood seems to not w as strong at these doses however not seeing anyone and been stressed lately so well see if that changes
09-02-2012, 07:37 PM
09-02-2012, 08:20 PM
09-02-2012, 09:08 PM
09-03-2012, 10:21 AM
Thanks.Originally Posted by domore
We need as much support as we can get to really make things fly.
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