The original, original Activate Xtreme made my joints feel great, several different mechanisms for the analgesic effect, and I felt amazing through the whole ordeal. However, when DS version came out (which was basically the exact same formula), I didn't get the analgesic effect of sense of well-being... could have very easily just been a change in the biochemistry of my body after a few years of having not taken it, however. The new, reformulated version obviously has a different ingredient profile, but it looks pretty impressive.