Guest viewing limit reached
  • You have reached the maximum number of guest views allowed
  • Please register below to remove this limitation

Oops...7-Hydroxy thread

To answer Wojo's question in the now deleted thread, I don't know why it wouldn't work as a transdermal as long as you are using a lipophilic carrier. I believe the mw of the alpha metabolite is below 500.
 
yea i been out of this for so long i forget what t-gel is..lip would be absolved ..correct?
 
I thought that we had discussed this back in the day with Sledge when he was designing LX....although I can't remember what was said about it......wish I could remember to take my piracetam so that I can remember things like this :D
 
jcam222 said:
ohhh nice.............hmm now I have to start looking for a thread on making a PFO from this.
Click to expand...

You tell me and easy way to esterfy it... Ill make the PFO recipe. :box:

Adams
 
Mat, you got a purity test for this? Or had it independantly tested?

Good 7OH is a nightmare to source. There are loads of chem houses who claim they can, but their samples (i'm talking in the 8-10 region here) all tested out bad. That is why LX has been out of stock for so long.

We've only recently found a good source for it.
 
DAdams91982 said:
7-OH... same as LX.

Adams
Click to expand...


Not entirely correct. Looks like Custom's 7-hydroxy is both the 7alpha-hydroxy-DHEA (7alpha-OH-DHEA), and 7beta-hydroxy-DHEA (7beta-OH-DHEA) metabolites of 7-oxo-dhea. I believe 7-oh is just the alpha metabolite.
 
Robboe said:
Mat, you got a purity test for this? Or had it independantly tested?

Good 7OH is a nightmare to source. There are loads of chem houses who claim they can, but their samples (i'm talking in the 8-10 region here) all tested out bad. That is why LX has been out of stock for so long.

We've only recently found a good source for it.
Click to expand...


Really? IIRC, I thougt I had read differently in one of Steve's posts. Perhaps I am mistaken. In any event, I should have a lab report posted soon with a few others I am waiting on.
 
bow said:
Not entirely correct. Looks like Custom's 7-hydroxy is both the 7alpha-hydroxy-DHEA (7alpha-OH-DHEA), and 7beta-hydroxy-DHEA (7beta-OH-DHEA) metabolites of 7-oxo-dhea. I believe 7-oh is just the alpha metabolite.
Click to expand...

No, no, not true.

LX is a blend of alpha and beta with a particular ratio that we do not disclose. That's why we just have "7-Hydroxy-dehydroepiandrosterone" written on the label.
 
custom said:
Really? IIRC, I thougt I had read differently in one of Steve's posts. Perhaps I am mistaken. In any event, I should have a lab report posted soon with a few others I am waiting on.
Click to expand...
Which Steve? TP?

It may be easy to cook up, i dunno, but apparently most chem houses can't do that properly based on the sample testing we did.

Looking forward to the lab assay.
 
Last edited:
DAdams91982 said:
You tell me and easy way to esterfy it... Ill make the PFO recipe. :box:

Adams
Click to expand...

Theoretically, fischer esterification is not supposed to be extraordinarily difficult. There's a thread on here somewhere in which Chemo discusses it and gives instructions. I looked, but I can't seem to find it.

Hopefully, custom can get a source for the esterfied 7-OH and we won't have to worry about adding the ester ourselves. :cheers:
 
Actually I remember when SLEDGE first release LX he had three versions, a PFO, a oral, and a trans. I believe JMinis used the trans, maybe he can chime in. I am sure 7OH is fine orally as we have seen with LX, but wouldn't trandermally make it that much better? Would Stryders Penetrate be ok to dissolve this in, with maybe some DMSO? Maybe this can be the poor man's version of AB-Solved even though it is still be carried from the last batch!
 
Atlas said:
Actually I remember when SLEDGE first release LX he had three versions, a PFO, a oral, and a trans. I believe JMinis used the trans, maybe he can chime in. I am sure 7OH is fine orally as we have seen with LX, but wouldn't trandermally make it that much better? Would Stryders Penetrate be ok to dissolve this in, with maybe some DMSO? Maybe this can be the poor man's version of AB-Solved even though it is still be carried from the last batch!
Click to expand...

The trans never happend... it may have been done himself... but DS never took off with the trans... it is strong via oral.

adams
 
Well I do remember him Preselling a beta batch, but that was it! I really hope Jminis can chime in here as I believe he tested it out and liked it! But trust me it did exist!
 
Robboe said:
No, no, not true.

LX is a blend of alpha and beta with a particular ratio that we do not disclose. That's why we just have "7-Hydroxy-dehydroepiandrosterone" written on the label.
Click to expand...


Interesting. Not what 1fast's site reads. From the attached link:

"7-OH(tm) Contains: 50 mgs 7-OH (tm) (7alpha- hydroxy-dehydroepiandrosterone)"

Invalid Link Removed
 
wojo said:
im asking about trans because im lazy and hate capping..im horrible at it:frustrate
Click to expand...

I hate capping too.

The PFO is neither oral nor transdermal. Sustained release, so no need for multiple doses per day.
 
jrkarp said:
I hate capping too.

The PFO is neither oral nor transdermal. Sustained release, so no need for multiple doses per day.
Click to expand...

ok whats pfo? ur making it sound like a suppository..lol..its its not oral or trans its (_!_):nono:

no needles for me either
 
bow said:
Interesting. Not what 1fast's site reads. From the attached link:

"7-OH(tm) Contains: 50 mgs 7-OH (tm) (7alpha- hydroxy-dehydroepiandrosterone)"

Invalid Link Removed
Click to expand...

Its wrong. The rest of that page just says 7-hydroxy-dehydroepiandrosterone.

That issue was from the old mini-description that strat wrote.
 
custom said:
Really? IIRC, I thougt I had read differently in one of Steve's posts. Perhaps I am mistaken. In any event, I should have a lab report posted soon with a few others I am waiting on.
Click to expand...

It taking a bit more than expected to get all the tests in I recently had, so I'll just out this up now.

Invalid Link Removed
 
7-beta cannot convert to 7-oxo in the body, only 7-alpha can. It is the interconversion between 7-alpha and 7-oxo that is the real meat and potatoes for cortisol suppression (they compete for the same enzyme that converts the inert cortisone to the active cortisol).

7-beta is good for thyroid and possible neurodegenerative theraputic effect.
 
custom said:
It taking a bit more than expected to get all the tests in I recently had, so I'll just out this up now.

Invalid Link Removed
Click to expand...

Told you it was hard to cook.

Good thing you changed your page to say "7-hydroxy-DHEA powder" and not 7-alpha/beta.
 
I'd like to see some data showing the beta is useless in cortisol suppression. From the little bit I have read leads me to think this is quite far from being bunk.
 
Do you not carry original 7-OXO anymore??? I like my orignal Absolved formula, but would rather support you than a non boards sponsor.

Adams
 
Robboe said:
You don't need to take 7OH transdermally. It does orally, what 7-oxo does transdermally.
Click to expand...

What about putting 7OH into an aqueous solution rather than pill form. Would it be better in an alcohol, PG, or some other solvent? Also, does anyone know if it would breakdown in an aqueous solution?
 
Robboe said:
7-beta cannot convert to 7-oxo in the body, only 7-alpha can. It is the interconversion between 7-alpha and 7-oxo that is the real meat and potatoes for cortisol suppression (they compete for the same enzyme that converts the inert cortisone to the active cortisol).

7-beta is good for thyroid and possible neurodegenerative theraputic effect.
Click to expand...

Sorry for the repost of this question - I didn't realize it would end up on a new page, but given what Robboe said - and the fact that CNW bulk 7-Hydroxy DHEA is all 7-beta (no 7-alpha) does this mean that this particular item is useless for cortisol suppression?
 
Not at all from what I have read. More or less (and rightfully so) downgrading a like product is understandable.
 
You must log in or register to reply here.
Back
Top