IBE Reverse: What do you think?

[strategicmove]

...
Now I see why you are so excited about your "baby". Your potential market is huge...way beyond the bodybuilding community.

Make sure you file a patent application that also includes you not just IBE....

I could not agree more, DB. I saw the following in the Life Extension Magazine. You probably have seen it, too:

GlaxoSmithKline Invests in Resveratrol Research

For years Life Extension magazine has been reporting on the multiple health benefits of resveratrol. We have urged members to incorporate this vital nutrient into their personal life-extension program. Now, pharmaceutical companies see the financial potential of creating a prescription drug from resveratrol compounds in order to treat age-related disease. Recently, pharmaceutical giant GlaxoSmithKline announced that it would acquire all outstanding shares of Sirtris Pharmaceuticals for $720 million in order to cash in on the life-extending promise of resveratrol-based compounds.1

Found in red grapes and wine, resveratrol has been credited with extending life span in a variety of organisms.2,3 Resveratrol mimics the life-extending properties of caloric restriction by activating enzymes called sirtuins, which influence a variety of aging-related metabolic functions.

Sirtris was founded in 2004 after Dr. David Sinclair of Harvard Medical School began publishing findings regarding resveratrol’s remarkable potential benefits.2 Sirtris’ stated goal is to discover and develop small molecules with anti-aging potential, and its research efforts have largely focused on enhancing the potency of resveratrol-based compounds.

GlaxoSmithKline evidently hopes to modify the resveratrol molecule to further bolster its bioavailability and effects. Such a modification would also allow the drug company to patent the new molecule and market it exclusively.

—Dale Kiefer

Reference

1. Available at: http://www.gsk.com/media/pressreleas...ease_10038.htm. Accessed April 30, 2008.
2. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6.
3. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.

[LakeMountD]

I could not agree more, DB. I saw the following in the Life Extension Magazine. You probably have seen it, too:

GlaxoSmithKline Invests in Resveratrol Research

For years Life Extension magazine has been reporting on the multiple health benefits of resveratrol. We have urged members to incorporate this vital nutrient into their personal life-extension program. Now, pharmaceutical companies see the financial potential of creating a prescription drug from resveratrol compounds in order to treat age-related disease. Recently, pharmaceutical giant GlaxoSmithKline announced that it would acquire all outstanding shares of Sirtris Pharmaceuticals for $720 million in order to cash in on the life-extending promise of resveratrol-based compounds.1

Found in red grapes and wine, resveratrol has been credited with extending life span in a variety of organisms.2,3 Resveratrol mimics the life-extending properties of caloric restriction by activating enzymes called sirtuins, which influence a variety of aging-related metabolic functions.

Sirtris was founded in 2004 after Dr. David Sinclair of Harvard Medical School began publishing findings regarding resveratrol’s remarkable potential benefits.2 Sirtris’ stated goal is to discover and develop small molecules with anti-aging potential, and its research efforts have largely focused on enhancing the potency of resveratrol-based compounds.

GlaxoSmithKline evidently hopes to modify the resveratrol molecule to further bolster its bioavailability and effects. Such a modification would also allow the drug company to patent the new molecule and market it exclusively.

—Dale Kiefer

Reference

1. Available at: http://www.gsk.com/media/pressreleas...ease_10038.htm. Accessed April 30, 2008.
2. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6.
3. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.

This is why when Fitnecise over at bb.com starts bashing Resveratrol and how it won't amount to anything etc etc etc. I just sit back and smile, because big pharma doesn't get involved unless there is potential.

[strategicmove]

... big pharma doesn't get involved unless there is potential.

Yep! Depending on the relative superiority of IBE Reverse/Triacetylated Resveratrol, GlaxoSmithKline might just consider making IBE a nice acquisition offer!

[LakeMountD]

Yep! Depending on the relative superiority of IBE Reverse/Triacetylated Resveratrol, GlaxoSmithKline might just consider making IBE a nice acquisition offer!

Hahaha riiiiight, somehow I see that one getting messy ;-). "Give us your company or we will decimate you!" lol

[datBtrue]

Hahaha riiiiight, somehow I see that one getting messy ;-). "Give us your company or we will decimate you!" lol

OR have the right "plugged in" white-shoes law firm represent you and "the boys" may let you have a taste.

[LakeMountD]

OR have the right "plugged in" white-shoes law firm represent you and "the boys" may let you have a taste.

Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.

[rykkk]

Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.

Is this the calm before the Grand Announcement "Reverse is finally here"?

[rykkk]

Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.

Is there any news on Reverse? It's the end of July.

[alan1973]

exercise in a pill, and reservatol is mentioned as well!
http://www.nytimes.com/2008/08/01/sc...=1&oref=slogin

[rykkk]

Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.

Please .......... any updates?

[LakeMountD]

As always we are just waiting on one last company to finish up what they are doing so we can move forward. We already have the ingredients so there is no problem there. I will get some testers this week .

[mrchristian]

As always we are just waiting on one last company to finish up what they are doing so we can move forward. We already have the ingredients so there is no problem there. I will get some testers this week .

I am salivating....

[LakeMountD]

I am salivating....

LoL as am I. It has been a nightmare trying to get everything together. When you are trying to coordinate 4-5 different businesses it is always tough.

[alan1973]

LoL as am I. It has been a nightmare trying to get everything together. When you are trying to coordinate 4-5 different businesses it is always tough.

would love to test for ya if I could. I am already spreading the news and the website amoung folks at work. folks here always ask me for supplement advice.
I can also maybe swing some folks to check it out at AlinBoard for ya since I am a respected member there.

[rykkk]

Hahaha riiiiight, somehow I see that one getting messy ;-). "Give us your company or we will decimate you!" lol

No news! That's scary. Makes me wonder if Glaxo Smithkline is indeed trying to do a hostile take-over of IBE.

That aside, when will Reverse be available to us?

[LakeMountD]

No news! That's scary. Makes me wonder if Glaxo Smithkline is indeed trying to do a hostile take-over of IBE.

That aside, when will Reverse be available to us?

I posted a new thread in the IBE forum here! Pre-orders are ready to go. They are actually moving very quickly and there are limited quantities so if you want to secure yours I suggest you do it soon

[corsaking]

Interesting read about reservatrol on this link

http://lpi.oregonstate.edu/infocente...dex.html#intro

[rykkk]

I posted a new thread in the IBE forum here! Pre-orders are ready to go. They are actually moving very quickly and there are limited quantities so if you want to secure yours I suggest you do it soon

Thanks for update -- I placed my order .....I'm all psyched!!

Just a few questions: 1) How many capsules per bottle? 2) What quantity of Triacetylated Resveratrol per capsule? and 3) Can I expect to receive this within a week's time as I leave for vacation in just over a week?

[Whacked]

Pardon the ignorance but isnt this similar to how CLA works?

(via PPAR-deta expression)

""Dr. Evans and his team found that the PPAR-delta protein remodeled the muscle, producing more of the high-endurance Type 1 fiber. They genetically engineered a strain of mice whose muscles produced extra amounts of PPAR-delta. These mice grew more Type 1 fibers and could run twice as far as on a treadmill as ordinary mice before collapsing.

Given that people cannot be engineered in this way, Dr. Evans wondered whether levels of the PPAR-delta protein could be raised by drugs. Pharmaceutical companies have long tried to manipulate PPAR-delta because of its role in fat metabolism, and Dr. Evans found several drugs were available, although they had been tested for different purposes.
"""

Interesting read about reservatrol on this link

Linus Pauling Institute at Oregon State University

[Whacked]

???