IBE Reverse: What do you think?
- 07-28-2008, 04:29 AM
I could not agree more, DB. I saw the following in the Life Extension Magazine. You probably have seen it, too:
GlaxoSmithKline Invests in Resveratrol Research
For years Life Extension magazine has been reporting on the multiple health benefits of resveratrol. We have urged members to incorporate this vital nutrient into their personal life-extension program. Now, pharmaceutical companies see the financial potential of creating a prescription drug from resveratrol compounds in order to treat age-related disease. Recently, pharmaceutical giant GlaxoSmithKline announced that it would acquire all outstanding shares of Sirtris Pharmaceuticals for $720 million in order to cash in on the life-extending promise of resveratrol-based compounds.1
Found in red grapes and wine, resveratrol has been credited with extending life span in a variety of organisms.2,3 Resveratrol mimics the life-extending properties of caloric restriction by activating enzymes called sirtuins, which influence a variety of aging-related metabolic functions.
Sirtris was founded in 2004 after Dr. David Sinclair of Harvard Medical School began publishing findings regarding resveratrol’s remarkable potential benefits.2 Sirtris’ stated goal is to discover and develop small molecules with anti-aging potential, and its research efforts have largely focused on enhancing the potency of resveratrol-based compounds.
GlaxoSmithKline evidently hopes to modify the resveratrol molecule to further bolster its bioavailability and effects. Such a modification would also allow the drug company to patent the new molecule and market it exclusively.
1. Available at: http://www.gsk.com/media/pressreleas...ease_10038.htm. Accessed April 30, 2008.
2. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6.
3. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.
- 07-28-2008, 11:25 AM
07-28-2008, 11:39 AM
07-28-2008, 11:53 AM
07-28-2008, 12:28 PM
07-28-2008, 01:14 PM
07-30-2008, 12:37 AM
07-31-2008, 06:43 PM
08-01-2008, 12:16 AM
08-05-2008, 06:26 AM
08-05-2008, 10:53 AM
As always we are just waiting on one last company to finish up what they are doing so we can move forward. We already have the ingredients so there is no problem there. I will get some testers this week .
08-05-2008, 10:59 AM
08-05-2008, 11:09 AM
08-05-2008, 11:33 PM
08-17-2008, 10:39 AM
08-17-2008, 11:16 AM
08-17-2008, 11:31 AM
08-17-2008, 03:23 PM
Just a few questions: 1) How many capsules per bottle? 2) What quantity of Triacetylated Resveratrol per capsule? and 3) Can I expect to receive this within a week's time as I leave for vacation in just over a week?
08-17-2008, 04:43 PM
Pardon the ignorance but isnt this similar to how CLA works?
(via PPAR-deta expression)
""Dr. Evans and his team found that the PPAR-delta protein remodeled the muscle, producing more of the high-endurance Type 1 fiber. They genetically engineered a strain of mice whose muscles produced extra amounts of PPAR-delta. These mice grew more Type 1 fibers and could run twice as far as on a treadmill as ordinary mice before collapsing.
Given that people cannot be engineered in this way, Dr. Evans wondered whether levels of the PPAR-delta protein could be raised by drugs. Pharmaceutical companies have long tried to manipulate PPAR-delta because of its role in fat metabolism, and Dr. Evans found several drugs were available, although they had been tested for different purposes.
08-23-2008, 12:02 PM
08-23-2008, 12:05 PM
I have never studied extensively anything related to CLA so I couldn't comment on it honestly.
08-25-2008, 08:59 PM
We are running a sale of this currently on IBE and it will be at Nutraplanet hopefully by the end of the week.
08-26-2008, 01:18 AM
Sounds good!Originally Posted by LakeMountD;
Product Educator | USPowders
Statements made by this online persona are the sole property of the owner, and do not necessarily reflect USPowders’ opinion as a whole.
08-26-2008, 07:58 AM
Superficiality of today's people amazes me (I guess I'm still naive IF IT INDEED AMAZES me). Speaking of the bodybuilders, many can't think outside of a square box. Extra muscle is dispensable for living, if you want to build more you have to create the right stimulus and provide the right building blocks. Because "the right stimulus" is inevitably a great stressor, you need to take care extra care of your health or you may as well flush all your gym efforts down the toilet.
Why do we have to bang our head against the wall until it cracks before we realize we shouldn’t have banged it in the first place ?!
Because humans are stubborn creatures and can only be convinced of inefficiency of their own methods through personal experiences :
Yep, I'm guilty too
08-26-2008, 08:45 AM
Is it not time to step back for moment for all of us to reflect on what we are doing , where we want to be in bodybuilding terms to see if we are being swallowed up and taken in by the amount of claims in advertising that some supplement companies engage in.
We have just had the 2008 olympics with 2012 not too far away.Maybe we should be looking to the guys and girls who came away with gold silver and bronze , to see just what it takes to get to the level they have in terms of training, diet and supplementation.Somehow i dont think they will be walking into a health food store or logging on to a online supplement company to try a supplement just because its flavour of the month
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