Neovar has completed it's Re-comp!!!!!!!!!!!

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    Quote Originally Posted by EasyEJL View Post
    yellow gold is sort of like an inflatable sex doll. Its not exactly plan A, but when you have no other option.....
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    Quote Originally Posted by Iron Lungz View Post
    In what way have you noticed an increase in Test?

    sleep, sorry. @_@

    I was sooooooo tired when I wrote this. The IGF-2 makes me want to catch up the rest that ive neglected due to all the work and school and papers I had to write. I noticed some better mornings feeling refreshed even after the first dosage.
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    Okay, what about a person like me who is a complete NON responder to monohydrate?
    •   
       

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    Thats a piece of the idea behind the formulation, even normal creatine nonresponders should respond to this.
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    Quote Originally Posted by paulg View Post
    Okay, what about a person like me who is a complete NON responder to monohydrate?
    That is a legitimate question. And you are not alone. As a matter of fact, I prefer to classify myself as a negative creatine-monohydrate responder, as I usually get adverse results (bloats and such discomfort) from it. Yet, I am confident this new version of NeoVar will address it, once I get my hands on it. How? Take another look at the agents in the formula. One important factor in creatine-monohydrate supplementation, like we all know, is efficient cellular absorption and optimization of phosphocreatine/ATP synthesis. To achieve this requires a combination of bioavailability/absorption enhancers and effective creatine co-factors. When you add D-Pinitol, Corosolic Acid, and Bioperine in the appropriate amounts to a simple monohydrate formula, you effectively turn creatine into a potent body-building weapon in a flash. D-Pinitol alone is one of the most effective creatine transporters and potentiators around. Add to that the glycogen-modulating effects of D-Pinitol, the bioavailability-and-absorption-enhancement properties of Bioperine, plus the insulin-mimicking benefits of corosolic acid, and you create an environment conducive for optimal creatine-monohydrate effectiveness. I frankly do not see how this formula cannot work, even for so-called negative responders or non-responders. I had never been this excited about a monohydrate-based product myself.
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    ^ What he said.
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    Quote Originally Posted by Lanbane View Post
    ^ What he said.


    x3
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    I would think even if your a non-responder to Creatine Mono the enhanced nutritional delivery and the longer lasting effects of this would be enough to make this product pretty top notch.
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    I cannot wait to drop a final piece of info on the forums..... one that will ensure you purchase Neovar. From now on.
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    Quote Originally Posted by Lanbane View Post
    I cannot wait to drop a final piece of info on the forums..... one that will ensure you purchase Neovar. From now on.
    I believe I alluded to it on the first page , but nobody caught it or asked about it.
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    Quote Originally Posted by EasyEJL View Post
    I believe I alluded to it on the first page , but nobody caught it or asked about it.
    The price?!?!

    You guys have my addy so you can send me that year supply of new NeoVar next month

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    Someone needs to convince me that this product has to be cycled! The usual argument that all supplements have to be cycled is not enough! Our bodies synthesize creatine daily from the amino acids glycine, arginine, and methionine. Besides, we also obtain creatine from diet (meat/animal sources). An average, healthy, 70kg athlete has creatine reserves of about 120gr. He uses up about 2.5gr - 3gr or so daily in metabolic processes, depending on his level of activity. Some of this creatine need is replenished via endogenous creatine synthesis and the rest directly from diet. Anyway, I weigh much more than 70kg, so I should be fine, if I supplemented with about 2gr-3gr of creatine daily, as long as absorption and bioavailability are optimized. And, by the way, I have not seen any evidence yet that suggests medium-to-long-term creatine supplementation in the 2gr-3gr daily suppresses or inhibits endogenous creatine synthesis.
    Last edited by strategicmove; 04-22-2008 at 04:31 AM.
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    Quote Originally Posted by strategicmove View Post
    Someone needs to convince me that this product has to be cycled!
    Nope. Not even gonna try
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    Well ill definately be picking this up as im tired of taking all these preworkout supps, i like my stuff in pill form so ill def be getting me some!
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    Quote Originally Posted by strategicmove View Post
    That is a legitimate question. And you are not alone. As a matter of fact, I prefer to classify myself as a negative creatine-monohydrate responder, as I usually get adverse results (bloats and such discomfort) from it. Yet, I am confident this new version of NeoVar will address it, once I get my hands on it. How? Take another look at the agents in the formula. One important factor in creatine-monohydrate supplementation, like we all know, is efficient cellular absorption and optimization of phosphocreatine/ATP synthesis. To achieve this requires a combination of bioavailability/absorption enhancers and effective creatine co-factors. When you add D-Pinitol, Corosolic Acid, and Bioperine in the appropriate amounts to a simple monohydrate formula, you effectively turn creatine into a potent body-building weapon in a flash. D-Pinitol alone is one of the most effective creatine transporters and potentiators around. Add to that the glycogen-modulating effects of D-Pinitol, the bioavailability-and-absorption-enhancement properties of Bioperine, plus the insulin-mimicking benefits of corosolic acid, and you create an environment conducive for optimal creatine-monohydrate effectiveness. I frankly do not see how this formula cannot work, even for so-called negative responders or non-responders. I had never been this excited about a monohydrate-based product myself.
    Okay, I am getting excited. What about Cinnulin PF (cinnamon)?
    Would this be beneficial to take with the new Neovar? Is it in the same league as the other partitioners (corsolic, d-Pinitol e.c.t.)? What about Tamarindus Indica, BPOV, 4-hydroxyisoleucine, K-R-ALA?
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    Quote Originally Posted by paulg View Post
    Okay, I am getting excited.
    I have been in that state for a while now!

    Quote Originally Posted by paulg View Post
    What about Cinnulin PF (cinnamon)?
    Would this be beneficial to take with the new Neovar? Is it in the same league as the other partitioners (corsolic, d-Pinitol e.c.t.)? What about Tamarindus Indica, BPOV, 4-hydroxyisoleucine, K-R-ALA?
    These compounds definitely demonstrate glucose-disposal/insulin-mimicking properties to different extents. In particular, though, extracted for corosolic acid and tannins, banaba extract is known to preferentially potentiate the action of GLUT-4 in muscle cells, while blocking the action of GLUT-4 in fat cells. I am not sure though, to what extent the other glucose-disposal agents you mentioned can replicate this mechanism. Net, I would start with the product as-is, to estimate the results from it. In the course of time, you may choose to add a complex that includes agents such as cinnamon, bitter melon extract, and 4-hydroxy-isoleucine, and see if any incremental benefits are discernible.
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    Quote Originally Posted by Mulletsoldier View Post
    This thread brings me back to high school, when your friend starts dating a girl who looks exactly like yours.

    lol mulllet...
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    Quote Originally Posted by strategicmove View Post

    These compounds definitely demonstrate glucose-disposal/insulin-mimicking properties to different extents. In particular, though, extracted for corosolic acid and tannins, banaba extract is known to preferentially potentiate the action of GLUT-4 in muscle cells, while blocking the action of GLUT-4 in fat cells. I am not sure though, to what extent the other glucose-disposal agents you mentioned can replicate this mechanism. Net, I would start with the product as-is, to estimate the results from it. In the course of time, you may choose to add a complex that includes agents such as cinnamon, bitter melon extract, and 4-hydroxy-isoleucine, and see if any incremental benefits are discernible.
    Tannic and Corosolic Acid promote anti-lipogenic activity primarily via lipid binding receptor deactivation, rather than GLUT4 deactivation in adipocytes; that action is present, but to a lesser-effective degree than the regulation of PPAR-Gamma2.

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    Okey Dokey.
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    Quote Originally Posted by Mulletsoldier View Post
    Tannic and Corosolic Acid promote anti-lipogenic activity primarily via lipid binding receptor deactivation, rather than GLUT4 deactivation in adipocytes; that action is present, but to a lesser-effective degree than the regulation of PPAR-Gamma2.

    I am well aware of the crucial role PPAR gamma plays in lipogenesis and adipocyte differentiation. While it is important to mention that the tannins in banaba extract provide the extract with its lipophobic (fat-repelling) properties, without which the extract is largely lipogenic (fat-attracting or fat-enhancing), and while it is important to mention that tannins reduce PPAR-gamma activity, it is also important to highlight the impressive role of corosolic acid in the GLUT-4 pathway. Both of these mechanisms make banaba extract an extremely useful agent in glucose disposal and lipolysis.
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    Quote Originally Posted by strategicmove View Post
    I am well aware of the crucial role PPAR gamma plays in lipogenesis and adipocyte differentiation. While it is important to mention that the tannins in banaba extract provide the extract with its lipophobic (fat-repelling) properties, without which the extract is largely lipogenic (fat-attracting or fat-enhancing), and while it is important to mention that tannins reduce PPAR-gamma activity, it is also important to highlight the impressive role of corosolic acid in the GLUT-4 pathway. Both of these mechanisms make banaba extract an extremely useful agent in glucose disposal and lipolysis.
    GLUT-4 inhibition in adipocytes is preventative for hypertrophy, but does not necessarily induce lipolysis . As I said, it is the regulative effects of both Corosolic Acid and Tannic Acid on PPAR-Gamma2 and lipid mRNA expression (cell transcription) which liberates, and prevents the further accumulation of, stored lipids. The GLUT-4 potentiating capacity of each compound is relegated primarily to mycoytes (muscle cells). This is exhibited further by the LDL and triglyceride lowering effect of both constituents of Lagerstroemia, leading to the conclusion its anti-lipogenic effect is through a direct pathway, and not GLUT-4 inhibition.

    As I said, the GLUT-4 potentiation is there, but it is not the primary anti-lipogenic pathway.
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    can someone include some willlow bark in the conversation cause i'm starting to get a headache from the scientific words
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    Willow Bark, 1, 2, 3, willow...bark.

    Good?
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    ah yes, thats better thx
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    Quote Originally Posted by Mulletsoldier View Post
    Willow Bark, 1, 2, 3, willow...bark.

    Good?
    well done
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    Ok, back to the non argumentative, not trying to talk big topic.....



    new Neovar will be cheaper. Not just by a buck or 2 either.......
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    tell us more, tell us more!
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    Quote Originally Posted by Lanbane View Post
    Ok, back to the non argumentative, not trying to talk big topic.....



    new Neovar will be cheaper. Not just by a buck or 2 either.......
    So I was right!?!?!?!

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    Quote Originally Posted by Lanbane View Post
    Ok, back to the non argumentative, not trying to talk big topic.....



    new Neovar will be cheaper. Not just by a buck or 2 either.......
    ^^^There is only one word to that should be heard after that statement....STAPLE! Nuff said!

    Cheers!
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    Quote Originally Posted by Lanbane View Post
    Ok, back to the non argumentative, not trying to talk big topic.....



    new Neovar will be cheaper. Not just by a buck or 2 either.......
    You are making it hard for me to take a break from neo. I cant effing wait until this releases so i can get some more!!
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    killin me too. although my remaining yellow gold capped up nicely
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    Quote Originally Posted by Mulletsoldier View Post
    GLUT-4 inhibition in adipocytes is preventative for hypertrophy, but does not necessarily induce lipolysis . As I said, it is the regulative effects of both Corosolic Acid and Tannic Acid on PPAR-Gamma2 and lipid mRNA expression (cell transcription) which liberates, and prevents the further accumulation of, stored lipids. The GLUT-4 potentiating capacity of each compound is relegated primarily to mycoytes (muscle cells). This is exhibited further by the LDL and triglyceride lowering effect of both constituents of Lagerstroemia, leading to the conclusion its anti-lipogenic effect is through a direct pathway, and not GLUT-4 inhibition.

    As I said, the GLUT-4 potentiation is there, but it is not the primary anti-lipogenic pathway.
    mRNA expression is a measure of PPAR gamma... Anyway, posts like ours never really end once they end up in a argumentative loop. We'll just be repeating the same things couched in different terms.
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    Quote Originally Posted by Lanbane View Post
    Ok, back to the non argumentative, not trying to talk big topic.....
    Agree!

    Quote Originally Posted by Lanbane View Post

    new Neovar will be cheaper. Not just by a buck or 2 either.......
    I already see myself doing the new NeoVar long-term!
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    Quote Originally Posted by metroba View Post
    You are making it hard for me to take a break from neo. I cant effing wait until this releases so i can get some more!!
    Why is taking a break an option? Just stick to the new NeoVar!
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    Quote Originally Posted by strategicmove View Post
    Why is taking a break an option? Just stick to the new NeoVar!
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    Quote Originally Posted by strategicmove View Post
    Agree!



    I already see myself doing the new NeoVar long-term!
    DUH! YOU get it for free!
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    It'll be cheap enough that everyone else will wanna stay on it too
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    argh it just need to appear. I was such a fool to not order any regular neovar
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    Quote Originally Posted by EasyEJL View Post
    argh it just need to appear. I was such a fool to not order any regular neovar
    Why do you regret not ordering the regular NeoVar, when you are looking forward to the launch of the new NeoVar? Besides, you can still order then regular NeoVar, right?
    Product Educator | USPowders
    Statements made by this online persona are the sole property of the owner, and do not necessarily reflect USPowders’ opinion as a whole.
  

  
 

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