Muscle building Androgens
Androstenedione, Androstenediol and Testosterone.
New research is showing that testosterone is not the only muscle building androgen! While testosterone is obviously the most researched androgen of the 21st century and the go to androgen for (TRT) testosterone replacement therapy, it is NOT the only androgen.
Several human and animal studies show that androstenedione and androstenediol have very potent muscle building effects (52, 53). The studies referenced in these articles suggest that testosterone was not the active androgen causing these lean muscle building effects. So who is doing all the work if its not our famous favorite hormone testosterone? The potent androgens androstenedione and androstenediol only caused only a mild increase in testosterone yet the animals and humans in these studies were gaining lean and losing body fat; almost as if they were on a super high dose of testosterone, interesting isn't it? (52, 53). This observation is also supported by test-tube studies showing that these androgens bind to the androgen receptor in muscle tissue and directly initiate muscle growth. (46-52).
Physical weakness is heavily correlated to low androgen levels. (1-8) Gaining lean mass and strength with low androgen levels is virtually impossible. (10-16) This is probably why some weaker men have such little faith in working out -- because it yields such minimal results -- men with low androgens can virtually block the body from gaining any muscle, or burning any fat from weight training and diet modification. (10-16) If you try to get stronger by working out when you have low androgen levels, it can actually lowers androgen levels.(9)
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