USPowders PureCAMP-95: The Purest Forkolin on the Planet about to hit the Planet - AnabolicMinds.com - Page 2

USPowders PureCAMP-95: The Purest Forkolin on the Planet about to hit the Planet

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    I apologize if this has been addressed. Has a price point and size been announced?
    Everything I say is fictional and for entertainment purposes only. Do not ask me for sources. I dont have any.

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    Quote Originally Posted by stankyleg View Post
    I apologize if this has been addressed. Has a price point and size been announced?
    No need for an apology. The selling size will be 2gr for $19.99. This should last more than 30 days at 60mg/day. Note that clinical trials used 50mg per day for known results. Alternatively, it can last 40 days at the human-trial dose of 50mg/day.
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    Quote Originally Posted by strategicmove View Post
    No need for an apology. The selling size will be 2gr for $19.99. This should last more than 30 days at 60mg/day. Note that clinical trials used 50mg per day for known results. Alternatively, it can last 40 days at the human-trial dose of 50mg/day.
    19.99 will be the highest price and the highest price is an incredible price...as Strategic said above.
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    Quote Originally Posted by CHAPS View Post
    Agreed, stacks very well with a high potency green tea, various forms of carnitine, tta would also be a good to add.
    Blast from the past! how are you?!
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    Quote Originally Posted by strategicmove View Post

    Yes, PureCAMP-95 is about to hit your favorite Planet! What is PureCAMP-95? Read on!

    PureCAMP-95 is a highly purified 95% Forskolin targeted to induce a wide variety of powerful effects. Benefitting from USPowders' unmatched excellence in bulk powders and unmatched value-for-money, PureCAMP-95 is a pluripotent agent specifically designed to deliver the following benefits, amongst others:

    - Pronounced cAMP activation without beta-adrenergic receptor down-regulation
    - Improved nitric-oxide synthesis, vascularity, and pump
    - Significant elevation of testosterone levels, nitrogen retention, and protein synthesis
    - Potent fat-loss (lipolytic and thermogenic) effects
    - Powerful anabolic and anti-catabolic effects, as well as radical improvements in dense, lean muscle mass, and definition
    - Dramatic improvements in ATP synthesis
    - Delayed onset of muscle fatigue, coupled with rapid recovery
    - Noticeable improvements in various metabolic markers


    To understand how PureCAMP-95 elicits these results, it is useful to review the following:


    The main active in the Ayurvedic herb, Coleus forskohlii, forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) possesses unique and potent bioactivity. In particular, forskolin’s central mechanism of action is the activation of an enzyme, adenylate cyclase, responsible for boosting cellular cyclic AMP (3,5 cyclic adenosine monophosphate (cAMP)) levels. Cyclic AMP is regarded by experts as the most important cell-regulating compound, and activates a host of other enzymes that influence (or are involved in) a multitude of different cellular functions. Recall the important role cAMP elevation plays in the stimulation of steroidogenesis in the Leydig cells via the cholesterol transfer protein, StaR (more later). By activating cAMP, PureCAMP-95 (95% pure forskolin) helps to trigger and sustain testosterone synthesis, leading to increased anabolic activity. Besides cAMP activation, forskolin appears to be able to influence the activity of many membrane transport proteins. Furthermore, and as is well-known, beta-2 adrenergic receptors (for example, epinephrine, ephedrine, Clenbuterol) work by activating cyclic AMP. They do this, however, by upstream stimulation of the beta adrenergic receptors, suggesting the possibility of beta-adrenergic receptor down-regulation over time. Forskolin, on its part, however, not only works synergistically with beta-adrenergic agonists, but presents no receptor down-regulation concerns, as it directly activates cyclic AMP without the need for prior activation of beta receptors.


    Slabs of scientific research have confirmed that forskolin has anabolic, anti-catabolic, lipolytic, thermogenic, and several ancillary, effects. Our primary interest in forskolin is to harness these effects, in particular its cAMP-elevating mechanism so as to induce considerable effects in terms of steroidogenic-spermatogenic-anabolic, lipolytic-thermogenic and anti-catabolic signaling. Secondarily, we also see an opportunity to exploit the ancillary benefits from forskolin.


    Now, let us zoom in further on PureCAMP-95. First, we examine forskolin’s more familiar lipolytic and thermogenic effects, as this will prepare the ground for describing its anabolic action. By activating cAMP in adipose cells, completely independently of epinephrine, forskolin activates an enzyme called hormone sensitive lipase (HSL), inducing considerable lipolytic action by liberating free fatty acids in adipocytes to be metabolized for energy. This occurs entirely without the need for any stimulant! Furthermore, forskolin promotes the elevation of thyroid activity, not only by stimulating the production of the thyroid hormones, T4 and T3, but also by promoting the conversion of T4 into the metabolically more active T3, via the enzymatic action of type II deiodinase. This leads to higher thyroid activity, translating into elevated thermogenic action expressed by the heightened oxidation of fatty acids. Furthermore, studies have shown that forskolin supplementation (over a period of 12 weeks) not only produced a significant reduction of fat mass, but also produced an increase in serum free testosterone levels, an outcome also relevant for forskolin’s anabolic effects.


    Before we devote attention to PureCAMP-95's anabolic and anti-catabolic actions, let us first indicate the significance of cAMP activation and cAMP levels, as cAMP has been mentioned several times already. Many disease states are associated with low levels of cAMP. These include, for example, angina, hypertension, obesity, asthma, psoriasis, to name a few. On the other hand, increased cAMP levels are known to, for instance, trigger StaR and steroidogenesis, stimulate the HPTA, reduce histamine release (with implications for allergic conditions), inhibit platelet aggregation, improve thyroid function, improve the contractile force of cardiac muscles, boost fat metabolism, and so on. Put simply, cyclic AMP and the host of downstream chemical actions and metabolic processes it activates, together form a complex second messenger system that modulates the intricate and powerful effects of hormones in our body.


    We now turn to PureCAMP-95's anabolic and anti-catabolic activity.


    Preamble: As we all know, testosterone, without doubt, is one of the most anabolic androgens known to science. The production of androgens, including testosterone, follows a powerful cascade of signals emanating from the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus (when the hypothalamus senses a low level of androgens or excess estrogen derived from aromatizing steroids and prohormones) to the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH), both gonadotropins secreted by the pituitary gland. In particular, LH and FSH, in turn, stimulate the Leydig cells (via LH) and the Sertoli cells (via FSH) of the male gonads (testicles) to amplify the production of androgens, including testosterone (a process also called steroidogenesis) and semen (a process also called spermatogenesis) respectively. FSH acts, not only by sensitizing the testes to the effects of LH (via the response of LH to luteinizing-hormone releasing hormone (LHRH)), but also by increasing the number of testicular LH receptors.


    To note, the synthesis of testosterone in the testes from cholesterol occurs via a cAMP-dependent boosting of the levels of a Leydig-cell cholesterol-transfer protein, known as steroidogenic acute regulatory protein (StaR). This particular point is an important motivation for our interest in a potent cAMP-boosting agent such as PureCAMP-95, to stimulate steroidogenesis and deliver dramatic surges in anabolism. These androgens, including testosterone, now produced by the Leydig cells, typically bind to intra-cellular androgen receptors, specifically activating so-called transcription genes. This means these steroidal molecules instruct the genes to act in a specific way, for instance, inducing anabolic effects such as increasing nitrogen retention and protein synthesis, reducing cortisol, increasing IGF, and so on. However, this process does not continue ad infinitum. To avoid excess production of testosterone, and to maintain hormone homeostasis, the body triggers the so-called negative feedback loop to instruct the hypothalamus to stop the release of GnRH, and consequently, to halt the production of testosterone in Leydig cells. This process can also be induced by administration of exogenous androgens and steroids, for instance during a steroid or pro-hormone cycle.


    In the case of a natural increase in testosterone production and a negative feedback loop triggered by natural hormone regulation, recovery of testosterone production resumes after a very short time-lag to maintain hormone homeostasis. This is actually a rhythmic (daily) process of activation and deactivation of testosterone production. In the case of a negative feedback loop triggered by exogenously infused androgens and steroids, such as during a cycle, recovery must be actively and specifically stimulated to re-introduce hormone homeostasis and quench catabolic processes. This is so, because during cycles, hormone levels attain chronically high levels, leading to a complete deactivation of the natural hypothalamic, pituitary, and gonadal interaction.


    Now, by triggering elevated cAMP, PureCAMP-95 helps activate an enzyme known as protein kinase A, that exerts a powerful effect on androgen receptor binding. Furthermore, by indirectly supporting improved androgen-receptor binding, PureCAMP-95 promotes higher androgenic activity, ultimately leading to greater anabolic activity (via specific gene transcription and the resulting increase in nitrogen retention, protein synthesis, and so on). To continue, as HPTA shutdown is partly due to low cAMP levels, forskolin-induced elevated cAMP also serves as a signal to the pituitary gland to secrete LH, which in turn signals the Leydig cells of the gonads to trigger the production of testosterone (steroidogenesis) by boosting levels of the so-called steroidogenic acute regulatory (StaR) protein, a Leydig cell cholesterol-transfer protein that plays a foundational role in the synthesis of testosterone. This cascade is important, because the activation of the steroidogenic enzymes involved in the synthesis of testosterone from cholesterol cannot occur without the prior activation of the StaR protein by cAMP. So, by dramatically boosting cAMP levels, PureCAMP-95 exerts a powerful anabolic effect via cAMP-induced LH secretion and the ultimate StaR-modulated synthesis of testosterone. In addition, as mentioned earlier, forskolin has also been shown to raise levels of free testosterone during a 12-week supplementation period, also adding to forskolin’s anabolic effects.


    PureCAMP-95's anti-catabolic action is also due to its effect on cAMP elevation. The breakdown of muscle tissue is predominantly governed by calcium-dependent enzymes, known as calpains. Fortunately, calpains can be inhibited by another agent known as calpastatin. Better still, the activation of calpastatin is cAMP-dependent, so that by activating cAMP, PureCAMP-95 exerts significant anti-catabolic action by supporting the activation of the caplain inhibitor, calpastatin, thus promoting the preservation of lean muscle tissue.


    So, PureCAMP-95 not only stimulates pathways that induce considerable fat loss, but also those that exert potent anabolic and anti-catabolic effects. Beyond these, PureCAMP-95 also has several ancillary effects such as vasodilation, bronchodilation, anti-glaucoma effect, and reduction of inflammatory activity, to name a few.


    Overall, PureCAMP-95 is a safe, reliable, effective, and incredibly versatile and pluripotent agent specifically engineered to deliver superior lipolytic, thermogenic, anabolic and anti-catabolic activity, as well as ancillary effects such as the regulation of vascular tone and promotion of the maintenance of metabolic and immune-system integrity.

    PureCAMP-95, the purest Forskolin on the planet should hit your favorite Planet by early next week or earlier.



    Use before bed and wake up leaner and leaner everyday....
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    Quote Originally Posted by CHAPS View Post
    Agreed, stacks very well with a high potency green tea, various forms of carnitine, tta would also be a good to add.
    How could I have missed your post? Hope all is well with you, buddy!
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    Can u recommend an affordable scale for weighing increments under 1/10 of a gram? Or would u just mix it with a ratio of bcaa or something? For instance, mix it in with 248 gm of bcaa and take 5 gms per day of the mixture, it would give u 50mg of purecamp per 5 gm serving.
    Everything I say is fictional and for entertainment purposes only. Do not ask me for sources. I dont have any.
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    Quote Originally Posted by stankyleg View Post
    Can u recommend an affordable scale for weighing increments under 1/10 of a gram? Or would u just mix it with a ratio of bcaa or something? For instance, mix it in with 248 gm of bcaa and take 5 gms per day of the mixture, it would give u 50mg of purecamp per 5 gm serving.
    There are scale options at NutraPlanet, I believe. If you choose to mix it with another powder, do it such that you get about 25-30mg PureCAMP-95 per dose. That way, you can take several doses per day, with little risk of gastrointestinal challenges.
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    Quote Originally Posted by USProduct-Edu

    Blast from the past! how are you?!
    Great buddy, yourself?
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    Quote Originally Posted by bpmartyr View Post
    I WANT CAPS!
    I hear ya bro..Just cap it yourself..I do it with my bulk cissus..takes 10 minutes max to cap 100 with nutra's capping kit
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    Quote Originally Posted by CHAPS View Post
    Great buddy, yourself?
    You always were the teachers pet Chaps!
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    Quote Originally Posted by R-Mac View Post
    I hear ya bro..Just cap it yourself..I do it with my bulk cissus..takes 10 minutes max to cap 100 with nutra's capping kit
    Indeed. The powder approach allows us to offer these great products at those prices. Capsules would raise production costs, and consequently, prices.
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    Quote Originally Posted by bpmartyr View Post
    You always were the teachers pet Chaps!
    Holy ****, a reunion! Like the Van Halen tour...
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    Quote Originally Posted by USProduct-Edu View Post
    Use before bed and wake up leaner and leaner everyday....
    plus Focus Dirt in the morning ROCK N` ROLL all day
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    I tried this stuff about 6 or 7 years ago. Ended up tossing it. Tasted like crap and didn't do a thing for me.
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    Quote Originally Posted by T-Bone View Post
    I tried this stuff about 6 or 7 years ago. Ended up tossing it. Tasted like crap and didn't do a thing for me.
    Was it 95% Forskolin? And how did you dose?
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    Quote Originally Posted by MAxximal View Post
    plus Focus Dirt in the morning ROCK N` ROLL all day
    That would be one nice stack. With Bulk 1-carboxy.
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    Quote Originally Posted by strategicmove View Post
    Was it 95% Forskolin? And how did you dose?
    I don't remember I think I took a teaspoon a day or something. It was back when Bulk Nutrition sold powders.
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    Quote Originally Posted by T-Bone View Post
    I don't remember I think I took a teaspoon a day or something. It was back when Bulk Nutrition sold powders.
    Probably not 95% Forskolin. One teaspoon of it per day would have been quite hefty, and would have done wonders.
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    Quote Originally Posted by USProduct-Edu View Post
    Use before bed and wake up leaner and leaner everyday....
    Stacked with Bulk 1-carboxy.
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    Quote Originally Posted by strategicmove View Post
    There are scale options at NutraPlanet, I believe. If you choose to mix it with another powder, do it such that you get about 25-30mg PureCAMP-95 per dose. That way, you can take several doses per day, with little risk of gastrointestinal challenges.
    I would personally suspend it in olive oil. The ability to perfectly dose that high of an extract would be ideal. Get hot spots usually when mixing with another powder.
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    Quote Originally Posted by USProduct-Edu View Post
    Holy ****, a reunion! Like the Van Halen tour...
    Haha, but better!
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    Quote Originally Posted by DAdams91982 View Post
    I would personally suspend it in olive oil. The ability to perfectly dose that high of an extract would be ideal. Get hot spots usually when mixing with another powder.
    I agree and plan on it!
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    VERY interested in this, always a fan of forskolin. Any third party tests for the 95% purity? I've been duped on bulk forskolin far too many times to buy without seeing extract tests.
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    Quote Originally Posted by DAdams91982 View Post
    I would personally suspend it in olive oil. The ability to perfectly dose that high of an extract would be ideal. Get hot spots usually when mixing with another powder.
    Or MCT-Oil. Great idea, by the way, a legitimate dosing alternative versus mixing with another powder.
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    Quote Originally Posted by mr.cooper69 View Post
    VERY interested in this, always a fan of forskolin. Any third party tests for the 95% purity? I've been duped on bulk forskolin far too many times to buy without seeing extract tests.
    I personally do not know if such a third-party test exists. Yet, any one that knows USPlabs/USPowders knows that we never (read never ever) short-change our customers in terms of raw-material purity or dosage amounts. Our legendary Forskolin product, Bolic (known to the veterans on this board and elsewhere) also contained a similar extract percentage and was famed for its effectiveness. For us, innovation, quality and effectiveness are a passion, and there is no way we would risk our hard-earned reputation (think Jack3d, OxyELITE Pro, PowerFULL, P-Slin, Anabolic Pump, Super Cissus, PRIME, ModernBCAA, Recreate, Pink Magic, Compound-20, Bulk 1-carboxy, and so on) by making a false claim on a product that may not even account for 3% of overall sales.
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    Quote Originally Posted by strategicmove
    Stacked with Bulk 1-carboxy.
    I'm thinkin of stacking this for 8 weeks this summer during pct and beyond. Torem 4 weeks, purecamp, and carboxy 8 weeks
    Everything I say is fictional and for entertainment purposes only. Do not ask me for sources. I dont have any.
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    Quote Originally Posted by stankyleg View Post
    I'm thinkin of stacking this for 8 weeks this summer during pct and beyond. Torem 4 weeks, purecamp, and carboxy 8 weeks
    I would add SuperSaponins to that stack, and you should be set.
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    would this be comparable to c-bolic?? because at the price id rather just pay 19.99 for a 30 day supply of the pills.
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    Quote Originally Posted by ericool007 View Post
    would this be comparable to c-bolic?? because at the price id rather just pay 19.99 for a 30 day supply of the pills.
    What is C-Bolic?
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    Coochie bolic. It helps with gettin the ladies.
    Everything I say is fictional and for entertainment purposes only. Do not ask me for sources. I dont have any.
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    Quote Originally Posted by stankyleg View Post
    Coochie bolic. It helps with gettin the ladies.
    Sorry, I am not familiar with the compound.
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    you guys are retarded

    c-bolic by better body sports just google it
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    Quote Originally Posted by ericool007
    you guys are retarded

    c-bolic by better body sports just google it
    Lol. Sorry bro. I couldn't resist
    Everything I say is fictional and for entertainment purposes only. Do not ask me for sources. I dont have any.
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    lol i thought you were serious
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    Quote Originally Posted by ericool007 View Post
    you guys are retarded

    c-bolic by better body sports just google it
    USPlabs years back has a product called Bolic pure authentic 95% Forslean


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    Quote Originally Posted by ericool007 View Post
    you guys are retarded

    c-bolic by better body sports just google it
    No one is retarded here. Please stay civil in this thread. Thank you!
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    Quote Originally Posted by MAxximal View Post
    USPlabs years back has a product called Bolic pure authentic 95% Forslean


    That was the classic!
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    Quote Originally Posted by strategicmove View Post
    That was the classic!
    Definitive
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    Got Glycophase ...?


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    does this need to be capped or can we throw it in our juice or drinks?
    S.n.S team member
  

  
 

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