Mind-Blowing Deal: Buy Compound-20 and Get Jack3d For Only $10!!! Limited Time Offer - AnabolicMinds.com

Mind-Blowing Deal: Buy Compound-20 and Get Jack3d For Only $10!!! Limited Time Offer

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    Mind-Blowing Deal: Buy Compound-20 and Get Jack3d For Only $10!!! Limited Time Offer


    Mind-Blowing Deal: Buy Compound-20 and Get Jack3d For Only $10!!! Limited Time Offer.


    See link at the end of the write-up.


    Compound-20 is a new-age leaning and hardening agent designed to deliver superior anabolic, anti-catabolic, and lipolytic effects. Composed of three carefully selected innovative, ultra-effective agents, namely N-Coumaroyldopamine, N-Caffeoyldopamine, and Symplocos Racemosa), Compound-20 works via several molecular mechanisms to induce enhanced "dry" lean mass, reduced adipose proliferation and expression, as well as increased anti-catabolic action. In particular, Compound-20 potently induces selective beta-2-adrenoceptor activity, stimulates Akt, mammalian target of rapamycin (mTOR), and growth-factor (insulin/IGF-2) signaling cascades, as well as pronounced hormone sensitive lipase (HSL) and cyclic AMP activity.


    First the adrenoceptors. Adrenergic receptors, or adrenoceptors, belong to the G-protein class of coupled receptors, and are the most prominent receptors in the adipose membrane, besides also being expressed in skeletal muscle tissue. These adipose-membrane receptors are classified as either alpha- or beta-adrenoceptors. Although these beta and alpha adrenoceptors share the same messenger, cyclic adenosine monophosphate (cAMP), the specific transduction pathway depends on the receptor type (alpha or beta). [Cyclic AMP is the messenger for beta adrenoceptors. Many disease states are associated with low levels of the second messenger system, 3,5 cyclic adenosine monophosphate (cAMP). These include, for example, hypertension, obesity, asthma, to name a few. On the other hand, increased cAMP levels are known to, for instance, stimulate lipolytic activity, trigger the levels of a Leydig-cell cholesterol-transfer protein, known as steroidogenic acute regulatory protein (StaR) and steroidogenesis, stimulate the HPTA, reduce histamine release (with implications for allergic conditions), inhibit platelet aggregation, improve thyroid function, improve the contractile force of cardiac muscles, boost fat metabolism, and so on. Put simply, cyclic AMP and the host of chemical actions and metabolic processes it activates, together form a complex second messenger system that modulates the intricate and powerful effects of hormones in our body, both lipolytic/anti-catabolic and anabolic.] By stimulating pronounced cAMP activation, Compound-20 exploits the downstream effects of cAMP action.


    To continue, Compound-20 also induces potent selective beta-2-adrenoceptor stimulation. The beta adrenoceptors, in particular the beta-2 adrenoceptors, are the most thermogenic and lipolytic adrenergic receptors, and also induce anabolic effects. In particular, the stimulation of beta-2 adrenoceptors triggers vasodilation in muscle tissue, promoting oxygen uptake and nutrient transportation to muscle tissue. Furthermore, beta-2 adrenergic receptors are direct thermogenic activators via stimulating direct increases in fatty acid oxidation. Increased oxidation of fatty acids in skeletal muscle cells promotes leaning. To continue, activation of beta-2 adrenoceptors directly upregulates uncoupling proteins 2 and 3 in skeletal muscle cells, leading to enhanced energy expenditure and impairment of the anti-lipolytic effects of alpha-2 adrenoceptors. Beta-3 receptors are also thermogenic activators and promote uptake of fatty acids into perixosomes and mitochondria, leading to the oxidation of fats, not carbohydrates, for energy. Beta adrenergic stimulation tends to exhibit a potential for anabolic activity. The specific anabolic activity of beta adrenoceptors depends in some cases on the duration of their interaction with receptors in skeletal muscle cells, or whether or not they bypass the liver (thus circumventing first-pass degradation). Examples of anabolic effects from beta-adrenergic stimulation include improved muscle strength, preservation of lean mass (anti-catabolic action), improved nitrogen retention and improved protein synthesis in skeletal muscles (even during caloric restriction).


    Now to the other molecular mechanisms of Compound-20 action. As is well known, the mTOR signaling pathway has a wide variety of functions that include the regulation of cell proliferation, cell growth, hypertrophy, and muscle protein synthesis (MPS). The activation of mTOR triggers translation initiation and translational control. Translation initiation involves a chain of events that are required to ensure ribosomal complex assembly and the binding of target mRNA. Furthermore, Compound-20 supports growth-factor (insulin/IGF-1) signaling. Growth factors stimulate mTOR activity. In addition, growth factors such as insulin and IGF-1 can also induce PI3K (phosphoinositol 3-kinase (PI3K) activation. PI3K activation usually ignites several downstream signaling events involved in cell differentiation and growth, with the serine/threonine kinase Akt/PKB (protein kinase B), being a downstream effector of PI3K. Akt/PKB phosphorylates glycogen synthase kinase 3 (GSK3), ultimately inducing an increase in muscle protein synthesis via enhanced action of eukaryotic initiation factor 2B (eIF2B). These pathways exploited by Compound-20 combine to deliver improved anabolic signaling (growth in dense lean mass), enhanced lipolytic activity, as well as pronounced anti-catabolism.


    To expand, Compound-20 stimulates cumulative positive changes in body, specifically via a pronounced improvement in lean-mass-to-fat-mass ratio, with noticeable aesthetic enhancements in muscular tone. As is well known, beyond being a storage unit for energy (as triacylglycerol) and acting as an insulator, adipose tissue is metabolically active. Usually, feeding should inhibit lipolysis via its stimulation of insulin release and the consequent impact on the enzyme, hormone sensitive lipase (HSL), the rate-limiting enzyme for lipolysis. On the other hand, fasting and exercise have the opposite (favorable) effect on lipolysis by reducing insulin and recruiting catecholamines such as noradrenaline (norepinephrine) and adrenaline (epinephrine), the main hormones involved in the regulation of lipid status. These catecholamines act as first messengers in the lipolytic cascade that lead to adrenoceptor (beta) activation and downstream activation of the second messenger (cAMP) that ultimately induces thermogenesis and lipolysis in visceral, subcutaneous, and gluteofemoral (buttocks and thighs) sites with varying results reflecting adrenoceptor distribution. So, the results seen on Compound-20 are consistent with the postulated adrenergic pathway to lipolysis and thermogenesis. Recall, too, that testosterone also upregulates beta-adrenoceptors in the abdominal and other regions, explaining one pathway it employs to induce lipolysis.


    Furthermore, as is well known, improved body recomposition is positively correlated with enhanced muscle definition, reduced fat expression, as well as enhanced leanness and vascular tone. Thanks to Compound-20, favourable body-compositional changes reflect the cumulative results of reduced adipogenesis, enhanced anti-catabolic/anabolic processes, as well as increased thermogenesis and lipolysis. The workings of Compound-20 in this area are similar to the pharmacological activities of agents that inhibit postprandial hypertriglyceridemia (excess fat accumulation in the blood after meals) and postprandial hyperglycaemia (excess glucose accumulation in the blood after meals); agents that stimulate increased resting metabolic rate or energy expenditure (via promoting thermogenesis and caloric expenditure); agents that induce an improvement in insulin sensitivity via promotion of glucose utilisation and inhibition of excess fat accumulation in adipose tissues; agents that stimulate thyroid function for enhanced lipolysis; agents that induce reduced gluconeogenesis (the production of new glucose from non-carbohydrate sources); agents that stimulate reduced cortisol expression (leading to reduced stress and lowered visceral fat dominance); agents that reduce the action of glycerol-3-phosphate dehydrogenase (the enzyme that converts blood sugar into triglycerides in fat tissue); agents that deliver direct or indirect anti-catabolic and anabolic effects; as well as agents that induce AMP-activated kinase (AMPK) activation (leading to the reduction in the action of glucose-producing enzymes and an increase in the action of glucose-consuming enzymes, effectively switching the body's system from fat-storage to fat-burning, including the inhibition of the class of nuclear receptor proteins termed peroxisome proliferator-activated receptor gamma (PPAR-gamma) that usually stimulate adipogenesis and fat storage. While many of these agents employ one molecular pathway to achieve their results, Compound-20 appears to uniquely use several of these pathways simultaneously to deliver thermogenic, lipolytic, anti-catabolic, and anabolic effects.


    Compound-20 is awesome solo, but also lends itself to a variety of stacking options, from a cutting, to lean-bulk and bulking regimes. Furthermore, it stacks exceptionally effectively with stimulant and non-stimulant blends.


    Now to Jack3d. Jack3d, a specifically designed pre-workout matrix, contains carefully selected agents that collectively enhance focus and concentration, stimulate vasodilation, boost endurance, strength, and stamina, reduce tissue fatigue, heighten performance, as well as enhance post-exercise recovery, to deliver one exceptional workout after the other. The feedback on Jack3d has been consistently impressive, making it the category champion it is.


    Stack Compound-20 and Jack3d to take your physique and performance to previously unknown levels!


    Take an advantage of the limited-time offer at NutraPlanet: Buy Compound-20 and get Jack3d for only $10!!!


    Click on the link below:
    USPLabs Compound + Jack3d Stack (combo pack): Discount Compound + Jack3d Stack Supplements









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    Compound 20 sounds like an interesting product, but the name reminds me of something from Resident Evil.
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    Dam nice deal!!!
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    Quote Originally Posted by VolcomX311 View Post
    Compound 20 sounds like an interesting product, but the name reminds me of something from Resident Evil.
    It is one truly versatile product.
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    Quote Originally Posted by punjabimunde View Post
    Dam nice deal!!!
    Absolutely.
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    Nice lookin' deal, Strat! Certainly worth jumping on.
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    Quote Originally Posted by MidwestBeast View Post
    Nice lookin' deal, Strat! Certainly worth jumping on.
    Indeed, especially because it is a limited-time offer, and as such it is not clear how long NutraPlanet would let it run.
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    Damn good deal right here, but actually g n c with their 20% and bogo 1/2 off deal makes getting 2 C20's a pretty good deal.
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    Quote Originally Posted by rulk22 View Post
    Damn good deal right here, but actually g n c with their 20% and bogo 1/2 off deal makes getting 2 C20's a pretty good deal.
    Great deal indeed. NutraPlanet has some of the best deals in the industry.
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    Wow. Nice!
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    Quote Originally Posted by FL3X MAGNUM View Post
    Wow. Nice!
    Juicy...
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    Quote Originally Posted by rulk22 View Post
    Damn good deal right here, but actually g n c with their 20% and bogo 1/2 off deal makes getting 2 C20's a pretty good deal.
    Bogo is a good deal...

    THis is deal is better. Stag is right. NP has the best deals
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    Stack Compound-20 and Jack3d to take your physique and performance to previously unknown levels!


    Take an advantage of the limited-time offer at NutraPlanet: Buy Compound-20 and get Jack3d for only $10!!!


    Click on the link below:
    USPLabs Compound + Jack3d Stack (combo pack): Discount Compound + Jack3d Stack Supplements
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    Take advantage of this rare opportunity, guys!
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    Bump for a legit oppurtunity...

    USPLabs is very solid in what they do.
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    Quote Originally Posted by AaronJP1 View Post
    Bump for a legit oppurtunity...

    USPLabs is very solid in what they do.
    Thank you for the support!
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    I cannot believe this stack (and price) is still available!
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