Text of S.4032 as Introduced in Senate: Designer Anabolic Steroid Control Act of 2010 - U.S. Congress - OpenCongress
even though it was a 2010 bill they are still wanting to ban it
This is a brand new prohormone from PHF/IBE, never seen before on the prohormone or pharmaceutical market.
This is a prohormone to the veterinary drug and black-market
bodybuilding steroid trenbolone. Unlike previous "tren" prohormones,
this one actually converts in the body to trenbolone. Previous "tren"
PHs converted to the structurally similar - but markedly weaker -
This prohormone has the same three conjugated double bonds as
trenbolone, and differs from it only in that this hormone has a
17-ketone, where trenbolone has a 17b-hydroxy function. In the body this
ketone will be readily hydrolysed by 17b-hydroxysteroid dehydrogenase
type 1 (17b-HSD1) into the active form, trenbolone.
Conversion to trenbolone should be high, so effects should be identical
to the injectable form - with the exception of the famed "tren cough".
Whatever the explanation for "tren cough" (and many have been
suggested), since it's a reaction to the sudden parenteral introduction
of some compound directly into the body, it's highly unlikely that any
orally administered compound will have the same effect.
Trenbolone is one of the strongest injectable steroids on the market, so effects experienced from Trenavar can be expected to be largely the same - huge strength and size increases, accelerated fat loss, and enhanced vascularity.
Blood pressure is likely to be dose-dependently elevated to a
significant degree, cholesterol levels and liver function markers are
likely to be adversely affected, though to what extent remains to be
seen. Commonly reported trenbolone sides include night-sweats, mood
swings, androgenic hair loss and/or growth, temporary loss of libido, as
well as the suppression of endogenous testosterone production, and it
would be sensible to assume that these may also result from use of Trenavar.
Metabolism and Bioavailability:
Warning: if you're not interested in advanced steroid metabolism
discussion, skip over this section. If you want solid info on how and
why an oral tren PH should work, read on.
The anabolic effects of trenbolone are due in part to the enhanced
androgen receptor binding that the conjugated double bond system causes
, and also because trenbolone is an antagonist of the glucocorticoid
receptor . The double bonds extending up the backbone of the steroid
flattens the steroid considerably, which makes it an excellent fit for
the androgen receptor. It also makes the molecule much more flexible
and therefore less receptor-specific . Trenbolone is incapable of
being affected by 5a-reductase, 5b-reductase, or aromatase. But will it
The first place to turn to for information on steroids is the seminal
1969 work Androgens and Anabolic Agents by Julius Vida. Unfortunately
this compound isn't among the 666 compounds discussed there, and there's
a shortage of information on trenbolone by oral adminstration. I was
fortunate enough to find a study which compared the anabolic effects of
oral and subcutaneous application of trenbolone in rats , and the
results were frankly startling. They found that to have a comparable
anabolic effect, trenbolone needed to be administered orally at 100
times the dosage as when administered by subcutaneous injection (see
graph). Sounds pretty bad for a tren PH then, right? Well, the good news
is we're not rats.
Trenbolone is metabolised differently in different species - in rats,
around 40% is excreted as a dione form, as well as several metabolites
hydroxylated in various positions , but in man only one metabolite
has been identified - the 17a-epimer .
The ratio of excreted trenbolone (17b-trenbolone) to epitrenbolone (17a-trenbolone) is estimated at 1:5 in a 24hr period .
What this means is that although Trenavar
is a prohormone to trenbolone, it doesn't appear to be a significant
metabolite in humans. The equilibrium of the reaction between 17-one and
17b-ol appears to be weighted heavily - in fact pretty much exclusively
- in favour of the 17b-ol, so Trenavar
should convert readily to the active form trenbolone. Once converted to
trenbolone, it will be open to the same metabolism mechanisms as
injectable tren - conversion via sulfatase to epitrenbolone and
excretion as glucoronides.
Of course, this is largely conjecture, since neither trenbolone nor a
precursor to it has ever been on the supplement market before... or has
A few years ago ALRI released an encapsulated product called "Methoxy
TRN", advertised as containing "17b-methoxytrienbolone". This was
quickly pulled from the shelves soon after its release, leaving only a
few highly-collectable bottles and a reputation for tremendous strength
and size gains and roadmap vascularity. This supplement was tested in
2008, and the researchers discovered the tell-tale mass spectra of
trenbolone (and no sign of the advertised methoxy group) .
An anti-doping study from 1996 found that orally administered trenbolone
was detectable by mass spectrometry for two to four days after a single
administration, unlike injectable trenbolone, which is detectable for
much longer . The detection of trenbolone after administration of Trenavar
is likely to follow similar lines, though detection methods may have
improved since then. Athletes subjected to doping tests should of course
avoid this and all other prohibited performance-enhancing products
Dosages and Cycle Durations:
Empirical evidence is the only way to determine this; once the product
has been used by enough people we'll have a better idea of how much, and
for how long, Trenavar is best used.
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