Originally Posted by scump
There is currently no literature that directly pertains to 1-Androsterone's conversion to 1-Adiol or 1-Adione. The best I could tell you is based off the older 1/4-AD studies and a study on the conversion of Androstenediol to testosterone.
In 2002 the Androstenediol study they were specifically looking at a sublingual Androstenediol hydroxypropyl-beta-cyclodextrin complex and it's impact on the homornal response in young males (Iowa State students). Note, this is the same complex used in 1-Andro RD for improved delivery.
In an older study they found that oral intake (100-200mg/day) of adiol and adione did not change serum testosterone concentrations in men. Thus the oral delivery route sucked for bioavailability.
Back to the study... They gave the subjects sublingual tablets that contained about 20mg's of adiol. There was also a placebo group. They measured serum Adione, total test, free test
, estradiol, but no cortisol unfortunately. Here were the charted results:
As you can see nearly all hormones measured in this study increased. Keep in mind some of these conversions are constantly moving and converting back and forth. So this was really just a 'snapshot' of what was occurring in the human body at the graphed time frames.
PA wrote a really good article about conversions that I posted here: PA on "Conversions"
If I had to guess it converts to a reasonable amount of 1-test (as well as other hormones). I say this simply because we have sold this compound for some time and anecdotally the results have been positive. Even if it does convert to some estradiol it is not necessarily bad on cycle as I'm sure you are aware.
Having said all that, this newest formulation is by far our best ever and should further improve results imo.