APS is looking for tester for Phenadrine "Superior Lipolytic Stimulant"
- 08-27-2008, 10:58 AM
- 08-27-2008, 11:20 AM
- 08-27-2008, 12:05 PM
Official Phenadrine write-up
Advanced Lipolytic Stimulant
Intense Workout Potentiator
Based on a carefully crafted unique matrix of proven and effective agents, coupled with advanced and highly innovative compounds at potent pharmaceutical-grade doses, Phenadrine effortlessly takes versatility and synergy to completely new levels. With a two-in-one punch, Phenadrine fuses advanced lipolytic stimulation and intense workout potentiation like no other supplement. A standard setter, Phenadrine will deliver results right from the first dose. Every time! No tolerance build up! No hit-and-miss! Phenadrine was engineered to work; to catapult your performance to a new league. Get ready for the most intense workout and fat-melting experience of your life!
· Unparalleled pre-workout and fat-incinerating results
· The most intense workout of your life. Every time!
· Intense focus, concentration, mental clarity and alertness
· Previously unknown levels of jitter-free energy with no crashes
· Dramatic boost in energy and physical performance
· Advanced multiple pathways for rapid and effective fat-loss
· Increased vascularity and pump
· Enhanced protein synthesis and elevated testosterone production
· Modulation of estrogen and cortisol levels
· Improved sexual performance
Serving size: 1 cap/60caps per bottle
750mg per (1) capsule
Engineered to unleash previously unknown levels of synergy, Phenadrine’s unsurpassed actives, including the novel and single most effective designer fat-loss compound, N-Methyl-Beta-Methylphenylethylamine HCL, collectively yield a new standard-setting advanced pharmaceutical-grade lipolytic stimulant and intense workout initiator. The matrix consists of:
08-27-2008, 12:06 PM
N-Acetyl-Tyrosine (NAT) is an acetylated form of the essential amino acid, L-Tyrosine. NAT is more water soluble, and is therefore, a rapidly absorbed and more bio-available form than pure L-Tyrosine. L-Tyrosine modulates the synthesis of cortisol and thyroid hormones, as well as that of neurotransmitter catecholamines such norepinephrine (noradrenaline), epinephrine (adrenaline) and dopamine, that are depleted by stress. So, NAT supplementation reduces the impact of stress and fatigue and elevates cognitive performance. The neurotransmitter-stimulation action of NAT further synchronizes with similar synergistic action from 1,3-Dimetylamylamine and caffeine (caffeine stimulates release of catecholamines and NAT modulates their synthesis), leading to enhanced thermogenesis and lipolysis. Furthermore, by modulating thyroid hormones, NAT supports optimised base metabolic rate, promotes protein synthesis and glucose metabolism, enhances lipid metabolism by increasing adipose tissue sensitivity to hormones that modulate fat breakdown. As is well known, even a slight increase in active thyroid-hormone levels can produce a dramatic improvement in metabolism, energy levels, and mental attitude. Besides, NAT’s cortisol-modulating impact supports reduced fatigue, better recovery, and reduced adipose storage.
An epimedium flavonoid and testosterone mimetic, icariin is a natural anabolic that possesses a variety of unique pharmacological actions in the body. It plays an important role in modulating nitric oxide levels by inhibiting an important enzyme, phosphodiesterase type 5 (PDE-5), that breaks down another enzyme, 3’,5’-cyclic Guanosine Monophosphate (cGMP). cGMP signals the smooth muscles to relax, enhancing blood flow. So, PDE-5 inhibition prolongs the action of cGMP, making possible the flooding of skeletal muscle tissue with nutrient-rich blood and oxygen, leading to improved muscle contraction, intense pump and vascularity, as well as promoting an environment conducive to anabolism. This PDE-5 inhibition is also the mechanism behind icariin’s dramatic improvement in sexual function in users. Furthermore, icariin, like testosterone, competes with glucocorticoids for receptor-site binding. By blocking glucocorticoids from binding to cortisol receptor sites, icariin inhibits cortisol action. This leads to an increase in the testosterone:cortisol ratio, triggering enhanced protein synthesis and anabolism. Furthermore, icariin produces a boost in cAMP levels, demonstrates estrogen-modulation properties, stimulates prolactin inhibition (via its action on dopamine receptors, thereby triggering an increased testosterone production), and promotes increased production of luteinizing hormone. Net, the cAMP elevation, selective cGMP inhibition, glucocorticoid antagonism, and estrogen modulation, all combine to improve the testosterone:cortisol and testosterone:estrogen ratios. Furthermore, via its function as an important acetylcholinesterase inhibitor, icariin boosts levels of the neurotransmitter, acetylcholine. This inhibition drives movement and promotes stronger muscle contractions, and a dense skeletal muscle structure.
Caffeine, a methylxanthine and popular stimulant, not only possesses lipolytic and appetite suppressant properties, but also helps to enhance endurance and extent the effect of other stimulants. As a CNS stimulant, caffeine works as an adenosine A1 and A2A receptor antagonist. This is significant because adenosine modulates the action of neurotransmitters such as dopamine, norepinephrine, and acetylcholine. Adenosine blocks the activity of excitatory neurotransmitters, creating a tatigue and a feeling of apathy. By antagonizing adenosine, caffeine stimulates nerve-cell activity, creating enhanced alertness and clarity. Furthermore, caffeine inhibits the enzyme, phosphodiesterase (PDE), that breaks down cAMP. This PDE inhibition leads to sustained cAMP activity and boosting norepinephrine, thereby up-regulating thermogenesis and lipolysis. These pathways ensure caffeine traces a synergistic action with 1,3-Dimethylamylamine and other agents in Phenedrine, creating an optimally fuelled fat-burning furnace in your body.
Something else: Two enzymes, arginase and nitric oxide synthase compete against each other for the nitric-oxide metabolic pathway. The enzyme arginase converts arginine to ornithine and urea. Nitric oxide synthase converts arginine to nitric oxide, the potent vasodilator. A higher expression of the arginase enzyme leads to higher ornithine production, but less nitric oxide production. Now enters caffeine (methylxanthine caffeine). Caffeine inhibits arginase activity. It does this by inhibiting the so-called adenosine receptors, leading to higher levels of free adenosine. Now, adenosine, adenine, inosine, and uric acid, are known to be competitive arginase inhibitors. Furthermore, caffeine and caffeine-related compounds, also produce arginase inhibition by raising norepinephrine and cAMP. The caffeine-triggered arginase inhibition produces an elevated expression of the nitric-oxide synthase enzyme. This means even more nitric oxide is made available, leading to stronger vasodilation (and pump).
Also known as Geranamine, 1,3-Dimethylamylamine, a derivative of geranium oil, possesses a pharmacological activity similar to that of epinephrine (adrenaline), the body’s endogenous chemical messenger. As a potent fat burner, 1,3-Dimethylamylamine activates an enzyme, adenylate cyclase, that elevates cyclic adenosine monophosphate (cAMP) in cells, triggering fat metabolism. This is also one of the chemical pathways employed by ephedrine to potentiate fat burning. Furthermore, 1,3-Dimethylamylamine demonstrates potent central-nervous system (CNS) stimulation, leading to enhanced energy and physical performance, heightened focus and concentration, enabling the user to achieve a previously unknown intensity during training. The user will experience a significant elevation in energy levels without the usual crash common with many other stimulants.
1,3-Dimethylamylamine is often combined with caffeine to further consolidate the heightened energy, intense concentration and focus, as well as euphoric feelings.
This is a truly unique and novel compound, and one of compounds that sets Phenadrine apart from competition. Chances are you are familiar with the pharmacological pathways of Beta-Phenylethylamine (PEA). You may also be familiar with N-Methyl-Beta-Phenylethylamine HCL. Yet, do not confuse N-Methyl-Beta-Phenylethylamine HCL with our much more potent agent, N-Methyl-Beta-Methylphenylethylamine HCL with several methyl groups that render it super stable and remorselessly effective. This novel agent works! That simple!
But why are PEA and its molecular derivatives even important for fat loss?
A remarkable compound, even in its pure form, Beta-Phenylethylamine (PEA), a catecholamine precursor and nutrient found in chocolate, is known to be a very clean stimulant with the remarkable ability to achieve central-nervous-system stimulation without producing nervousness or the jittery feeling associated with other stimulants. Like norepinephrine, the body’s most potent endogenous fat-burning hormone, PEA acts on alpha-receptors in the brain, triggering the release of the “feel-good” hormone, dopamine (3,4-dihydroxy-phenethylamine) in neural cells. PEA is also responsible for chocolate’s effect on mood, sense of satiety, reduced food cravings, mild euphoria, as well as increased metabolic rate (by modulating thyroid function). Also known as a neuromodulator, PEA promotes mental alertness, focus and concentration. By regulating catecholamines such as epinephrine (adrenaline) and norepinephrine (noradrenaline) that act on hormone-sensitive lipase, the rate-limiting enzyme in the mobilization of fatty tissue from storage cites, PEA elevates the metabolic rate, ultimately leading to increased fat burning. Unfortunately, PEA is rapidly metabolised in the body by type B monoamine oxidase and has a limited ability to cross the blood-brain barrier, thus preventing it from unleashing its full effects. The challenge was to obtain a form of PEA with a type B monoamine-oxidase inhibitor property. N-Methyl-Beta-Phenylethylamine HCL is an N-Methyl derivative of Beta-Phenylethylamine. This methylated form of PEA is dramatically more potent than pure PEA, and takes PEA’s CNS stimulation and fat-burning several notches higher. While we could have used this compound, we decided to aim still higher. Now enters N-Methyl-Beta-Methylphenylethylamine HCL. This novel and carefully engineered unique agent represents the most potent form of PEA ever developed. It is not an N-Methyl derivative of N-Methyl-Beta-Phenylethylamine HCL, rather an N-Methyl derivative of methylated Beta-Phenylethylamine HCL! It is like “double methylation”! Such compounds do not come more potent than this! Technically speaking, we astronomically boosted the pharmacokinetic value of PEA! This “double methylated” form unites the finest properties of PEA such as easily crossing the blood-brain barrier to elevate feelings of euphoria, intensifying fat-burning due to optimised beta-receptor agonism while demonstrating unprecedented stability to B monoamine oxidation, implying a longer-lasting and significantly more intensive overall action. Our N-Methyl-Beta-Methylphenylethylamine HCL is by far the most potent designer fat-loss agent ever developed, and you would not find it in many of fat-loss products around. It elevates the potency of our synergistic blend to never-before-seen levels! You will be convinced!
08-27-2008, 12:06 PM
Do not mistake this compound for pure synephrine! It is light years away, in terms of superiority. If synephrine worked for you, Methyl-Synephrine HCL will blow your mind! First, back to the basics. What is synephrine? Obtained from the citrus tree known as Citrus aurantium or Bitter Orange, synephrine is an active alkaloid with structural similarities to epinephrine and norepinephrine. Synephrine’s claimed thermogenic, lipolytic, and appetite suppression effects are derived from its alpha-adrenergic properties that provoke the activation of beta-3 receptors. The claim that synephrine’s beta-3-receptor binding triggers lipolysis at very high dosages appeared to based on Carpene et al (1999). Subsequent studies, e.g., Larsen et al (2002) and Bent et al (2004), however, demonstrated that beta-3-receptor agonists appeared to have dramatically less lipolytic action in human fat cells, compared to animal fat cells.
The picture, however, appears to change significantly with the use of a recently developed unique form of synephrine referred to as Methyl Synephrine. Using the methylated form of synephrine (derived by substituting or attaching a methyl group to different molecules) dramatically alters its pharmacological pathway, and appears to make the compound significantly more effective than pure synephrine. Methyl synephrine is an adrenergic amine that has unique and amplified pharmacological effects by acting, not only as a beta-3 receptor agonist, but also as an alpha-1 adrenergic agonist. This difference is significant, because pure synephrine is postulated to act as a beta-3-receptor agonist only. This means methyl synephrine works by significantly up-regulating the metabolic rate and enhancing fat metabolism and thermogenesis, while only mildly stimulating the central nervous system without adversely impacting blood pressure and heart function, unlike beta-2 receptor agonists such as ephedrine that trigger anxiety and irregular heartbeat. As a beta-3-receptor agonist, methyl synephrine up-regulates the action of epinephrine and norepinephrine (the most potent endogenous fat-burning agent around) within adipose tissue, leading to significant lipolysis. So methyl synephrine not only up-regulates fat breakdown (as a beta-3 receptor agonist), but also profoundly enhances the burning of released body fat for energy (as an alpha-1 agonist). Double punch!
As you can see, Phenadrine is no regular “kitchen-sink” formula. Rather, it represents a new standard in “double-punch” products that effectively combine intense-workout potentiating compounds with advanced lipolytic and thermogenic agents to deliver the performance you are looking for, and that we are known for. Our unique matrix of selected agents is delivered in pharmaceutical-grade purity and in potent per-dose-amounts that work every time. If you are looking for an effective double-punch product beyond the reach of competition, your search stops at Phenadrine! Advanced Lipolytic Stimulant. Intense Workout Potentiator.
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08-27-2008, 12:08 PM
great write up. looks good.
cant wait to try this
08-27-2008, 12:09 PM
08-27-2008, 01:50 PM
Just for clarification, APS - I applied to log this in the other thread http://anabolicminds.com/forum/aps-n...ml#post1512001
- I can transfer my app to this thread if this is where you want them.
08-27-2008, 02:23 PM
I am intrested in this Test
This will be my first time ever for presenting myself for any kind of trial testing
Here are some details for me please let me know how will you contact me or what will be the process
Serving size: 1 cap/60caps per bottle
750mg per (1) capsule
Age: 36 Years
Short term goal (cut, bulk, recomp, etc): Cut (lose Weight)
How long have you been training: 2 Months
Prior supplement use: None
Current supplements: Levithian Reloaded
ANY medication (OTC/Prescription): None
LINKS to past logs and/or reviews of ANY products: N/A
Will you post progress or before/after photos? Yes for Sure
08-27-2008, 05:28 PM
I am also interested in the Test
Here are my details. Feel free to contact me about this trial.
Age: 31 Years
Height/Weight: 5' 11"
Short term goal (cut, bulk, recomp, etc): Cut
How long have you been training: 1 year
Prior supplement use: None
Current supplements: None
ANY medication (OTC/Prescription): None
LINKS to past logs and/or reviews of ANY products: none
Will you post progress or before/after photos? Yes
08-27-2008, 08:02 PM
I posted in another thread to try a new stim, but will only do the first that I get into.
Age: 23 years
Height/Weight: 6'1''/ 207lbs @13.5% BF
Short term goal is to Cut
How long have you been training: 7 years off and on
Prior supplement use: Everything (Hydroxycut, Lipo 6, Diet Fuel, Xenedrine, Xenerdrine 8hr NRG, ECA, Drenilean, Trimethylean, Jet Fuel,)
Current supplements: Xceed, Multivitamin, Fish/Flax Oil, Ligament Health, Aminos.
ANY medication (OTC/Prescription): None
LINKS to past logs and/or reviews of ANY products: none yet
Will you post progress or before/after photos? Yes
08-27-2008, 08:13 PM
I'd have a hard time remembering any significant fraction of what i've taken fatburner wise. And nobody has listed clen, T3/T4, thyrotabs, T2, usnic acid, etc so far...
This space for rent
Phenadrol Log http://anabolicminds.com/forum/suppl...-hell-did.html - AMAZING fat loss results so far
08-27-2008, 08:23 PM
actually i believe i fit into the etc... category on that one Easy :-p
-Redline fat burner
08-28-2008, 12:03 AM
PLEASE!!!!!I've been waiting for something new!!!!
I jave been weanting and needing something so bad since I am training to lean out more, and have hit a plateau. Diet is clean but needs to be increased, and adding a suppllement like this would oonly help my workots, diet and goal.
Short term goal (cut, bulk, recomp, etc): Cut, tone, develop muscle in certain areas- abs, quads, shoulders- I want visible striations and vascularity,
How long have you been training: 4+ years
Prior supplement use: in the past 2 yrs, lipodene, t7, and lipodrene non stim, venom special tactics, lean dreams, gaspari thermotabs, recreate
Transdermals, lipoderm ultra, lipoderm y and napalm
Current supplementsccasional lipoderm ultra
ANY medication (OTC/Prescription): wellbuterin
LINKS to past logs and/or reviews of ANY products:Napalm
Will you post progress or before/after photos? you bet!
We prefer testers to be stimulant free for 2-4 weeks if applying to test this. no problem
08-28-2008, 08:04 AM
Height/Weight: 5'7.5'', 200 lbs.
Short term goal (cut, bulk, recomp, etc): Bulk and cut
How long have you been training: 1.5 years.
Prior supplement use: Axis Labs HemodrauliX/Muscle Delight, BSN Cell Mass/NO-Xplode/Syntha-6/Atrophex, Palo Alto Labs Aspire36/Paravol/Leviathan Reloaded, Scivation Xtend/Vasocharge, RPN Havoc/Thermo Glide/DCP/Atomic Meltdown, Animal Pak/Uni-Liver/Animal Cuts, MST Ragnarok/Somnidren-GH, Avant Research Napalm/Lipoderm-Ultra, ALR Industries Jungle Warfare, USP Labs Recreate/Super Cissus RX, Applied Nutriceuticals NeoVar, Anabolic Xtreme MassFX MS/Retain2, GDN Diesel Test Hardcore, Anabolic Innovations Cycle Support/Post Cycle Support.
Current supplements: N/A
ANY medication (OTC/Prescription): N/A
LINKS to past logs and/or reviews of ANY products: N/A
Will you post progress or before/after photos? I'd be happy to.
08-28-2008, 11:36 AM
08-28-2008, 04:18 PM
08-28-2008, 04:46 PM
Quite an interesting mix you got there. I'm surprised there aren't more entries, but it's understandable with all of the sponsored logs going on right now. This past month has been VERY active for AM loggers. I'll put in an app as a less/un-established logger to help out if necessary.
Until 6 months ago, I had never used a single stimulant (aside from a single dose of Lipo-6 that I did not react well to). I tenatively tried Recreate as a recomp agent and LOVED it. Since then, I've slowly added a few stims (core zap and an occasional Blast) into my workouts on a non-regular basis as a pickmeup on after-work workout days.
Height/Weight: 6'2 / 205 (having some strange fluxuations between 201-206 right now, measured naked upon waking)
Short term goal (cut, bulk, recomp, etc):
Finishing up a 6 month recomp (one month left), and moving into a clean bulk.
How long have you been training:
2 years back in college followed by 5 years of semi-sedentary code monkeying, lol. Been back in the gym for 6 months.
Prior supplement use:
Recreate, PowerFull, SizeOn, BSN Cellmass/NOXplode (ugh...), Green Magnitude, Core Zap (only 4 workouts with full dose so far), Nimbus Blast (used rarely as a get-the-f**k-out-of-bed supp).
REDuction (less than a week into a bottle, and will be able to put this on hold if necessary as it was a month-off-of-Recreate purchase), Anabolic Pump, Purple Wraath, Xtend, Ragnarok, bulk L-Tyrosine, ALCAR, Poseidon, Animal Pak, Sesamin, Fish Oil, bulk beta-alanine. These are mostly staples that do not change (Poseidon is a new one as of a few weeks ago).
NOTE: Blue Gene and PRIME are in the mail. I'm eager to supplement with these, but I dislike schizophrenic sponsored product logs. Will need your input on this, and would have to consider for a bit if it's necessary to postpone the use of these. Blue Gene is also being used to help repair some ligament/tendon damage, and I cannot postpone the use of this. I totally understand if these would disqualify me as a tester.
I am finishing up an adrenal reset (not from overdoing stimulants, but rather work stress and extreme/prolonged sleep deprivation (4.5 years averaging 2 hours/night or less during heavy and intense lifting scenarios in the workplace). I've accomplished this with Reset-AD and EndoAmp. The results have been better than expected.
ANY medication (OTC/Prescription):
None. Might start Protonix (acid reflux) in the future, but not likely during the course of this log.
LINKS to past logs and/or reviews of ANY products:
Purple Wraath Review
Anabolic Pump Review / before-after
Current Log (on hold for a week while CNS recovers)
Will you post progress or before/after photos?
Definitely before/after photos, but if the results permit, there will also be progress shots where applicable.
EDIT: I also plan to alter my training method/split soon, and am still researching protocols. I expect this to affect my results.
08-28-2008, 08:36 PM
i just switched to hypertrophy routine and after my WO yesterday i can honestly say i haven't been this sore in months.....something you might look into.
pm me if you need help with it (i've alrdy researched the hell outta it)
08-28-2008, 08:43 PM
Short term goal (cut, bulk, recomp, etc): Recomp ..
How long have you been training:i have been training around 10 months .. i have a personal trainer so i def have one of the best training routines out there and i really enjoy my time in the gym and push myself to the limits ..
Prior supplement use:RPM,SIZEON,SUMPERPRUMP,POW ERFULL,ZMK,WHEY,MULTI-V,CELLMASS AND CE2
Current supplements:NOTHING .. taking a 2 week break of all sups
ANY medication (OTC/Prescription):nope
LINKS to past logs and/or reviews of ANY products:sizeOn and RPM stack
(first log but hated the sizeon so i didnt even finish the log )
next one will be better !
Will you post progress or before/after photos? hell yeh !
08-28-2008, 09:03 PM
08-28-2008, 09:09 PM
This looks like a great product. I am going to try this out once I finish a bottle of SNS's synephrine product. Should be a good comparison.
08-29-2008, 07:09 AM
08-29-2008, 07:11 AM
09-01-2008, 08:05 AM
09-01-2008, 06:29 PM
09-01-2008, 07:27 PM
09-02-2008, 07:04 AM
this product looks solid wish i wasnt waiting for another item to log would definately shoot for this unless i can wait to mid oct to log it let me know
09-02-2008, 08:16 AM
09-04-2008, 12:32 PM
Congrats to the Phenadrine Testers
APS has chosen three people who will be testing our new product Phenadrine. To whose not chosen we will be looking for testers for another product in 10-14 days so stay tuned.
The winners are:
We look forward to your feedback.
09-04-2008, 01:48 PM
Excellent! I've been stim free for over a week in anticipation, and I look forward to the experience. thank you.
09-04-2008, 02:10 PM
09-04-2008, 02:19 PM
09-04-2008, 02:20 PM
09-04-2008, 02:40 PM
09-04-2008, 03:41 PM
- 5'10" 200 lbs.
- Join Date
- Jul 2007
awesome thanks guys. PM sent
Controlled Labs Head Board Rep
adam @ ControlledLabs.com
CONTROLLED LABS products are produced in a GMP for Sport certified facility
09-04-2008, 03:59 PM
09-04-2008, 04:29 PM
09-05-2008, 01:11 AM
09-05-2008, 01:21 AM
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