APS is looking for tester for Phenadrine "Superior Lipolytic Stimulant"

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  1. Age: 18

    Height/Weight: 6'2'' 184 12% bf

    Short term goal (cut, bulk, recomp, etc): bulk

    How long have you been training: 5 months

    Prior supplement use:
    -SuperPump 250
    -SizeOn
    -RPM
    -Drive
    -Neovar
    -Neovar recomped
    -Hypertrop X
    -REDuction
    -Glycergrow
    -Blue UP
    -Green Mag
    -Purple Wraath
    -HyperPump
    -Golden Finish
    -Thermotabs
    -NO3-Overload
    -NO Shotgun
    -Redline fat burner
    -noxavol
    -ZMK
    -Nocturnabol

    Current supplements:
    -HypertropX

    ANY medication (OTC/Prescription): none

    LINKS to past logs and/or reviews of ANY products:
    CL cut log
    AN log

    Will you post progress or before/after photos? always do

    *if chosen will quit taking stims from time of selection till receive product


  2. it a pity, I can't recall the last time I went 2 weeks stim free
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  3. 2 weeks is preferred not mandatory. We just dont want someone who has zapped out adrenals trying the product when they probaly would not feel anything, lol.

  4. Wow glad theres no yohimbine in it, I'll probably pick up a bottle when it hits nutraplanet.

  5. applied in the other thread. when do you guys plan to pick the testers?
    •   
       


  6. is this available for sale somewhere? i'm about to start a log for assault and bulletproof from musclepharm, but would like to try this. I did some web searches, but phenadrine only seems to show up as other products, not yours.

  7. It's a shame I'm starting a log from PAL next week.
    I just finished up 1.5 bottles of Reset AD so I'm 4 weeks stim sober.
    Oh well, I'm interested in what some of the stim junkies have to say about this product after trying it.
    "I am legally blind and if I can Squat,deadlift and over all get myself to the gym then anyone can get their a$$ in gear and get strong!!" - malleus25
    WHITE WHALE!

  8. Quote Originally Posted by EasyEJL View Post
    is this available for sale somewhere? i'm about to start a log for assault and bulletproof from musclepharm, but would like to try this. I did some web searches, but phenadrine only seems to show up as other products, not yours.
    We are set to release the product today so you will see it at major retailers next week. We are not currently carried by Nutraplanet but feel to reccomend our company in their forum. Yes, that is a shameless request

  9. Be sure to check out the APS forum for the new Phenadrine write-up. I will let the author of this fine write-up chime in if he wants it announced.
  10. Needing more applications for testers.


    Come on peeps..we need some more applications for tester.

  11. that or you could just choose the alrdy submitted ones

  12. lol now i see why you cant do that....not even a handful of apps

  13. App. removed due to increased applicant pool. Good luck gentlemen.

    Lets get some more applicants in here!
    Last edited by SilentBob187; 08-28-2008 at 10:50 PM.
    "I am legally blind and if I can Squat,deadlift and over all get myself to the gym then anyone can get their a$$ in gear and get strong!!" - malleus25
    WHITE WHALE!

  14. Age: 36

    Height/Weight: 5'10" currently 168.

    Short Term Goal: Recomp and bulk back up to my former weight of 187 after almost a year off. Also seeking a stim that can aid with the sort of work I do..long days hiking around in rough terrain.

    Years of training: 15

    Prior stim use: ECA, Yohimbine/Yohimbe, geranium oil, Drive, RPM, Fyre, Sulbutiamine, PEA, L-Tyrosine, ALCAR, PLCAR, Choline, and lots of caffiene.

    Current Supplements: Multi vitamin/minerals, Poseidon, fish oil and Relora.

    Too many reviews to dredge up.

    If the results are great and I can keep diet/training on track the entire time, then I will post photos.

  15. Quote Originally Posted by drummaboyzl View Post
    lol now i see why you cant do that....not even a handful of apps
    Now that's really showing your age.you are awfully judgemental for someone who quotes the bible!On a more positive note bioman looks like someone very experienced with these types of products would love to see some feedback from him as i believe it would be backed by a good amount of experience.looks like a good product,I'll give it a whirl.

  16. huh? lol im not mad, derogatory, or out of place.
    read the post prior to that one if u wanna know why i said that.

    lol his first post and hes trying to call me out

  17. Quote Originally Posted by drummaboyzl View Post
    huh? lol im not mad, derogatory, or out of place.
    read the post prior to that one if u wanna know why i said that.

    lol his first post and hes trying to call me out
    Not "calling you out" at all.Just thought you were saying that in an unnecessary inflamatory manner.But if you say that's not how it was intended,you would know better than i.Comment retracted.
  18. Official Phenadrine write-up


    Phenadrine
    Advanced Lipolytic Stimulant
    Intense Workout Potentiator

    Based on a carefully crafted unique matrix of proven and effective agents, coupled with advanced and highly innovative compounds at potent pharmaceutical-grade doses, Phenadrine effortlessly takes versatility and synergy to completely new levels. With a two-in-one punch, Phenadrine fuses advanced lipolytic stimulation and intense workout potentiation like no other supplement. A standard setter, Phenadrine will deliver results right from the first dose. Every time! No tolerance build up! No hit-and-miss! Phenadrine was engineered to work; to catapult your performance to a new league. Get ready for the most intense workout and fat-melting experience of your life!

    Phenadrine delivers:

    · Unparalleled pre-workout and fat-incinerating results
    · The most intense workout of your life. Every time!
    · Intense focus, concentration, mental clarity and alertness
    · Previously unknown levels of jitter-free energy with no crashes
    · Dramatic boost in energy and physical performance
    · Advanced multiple pathways for rapid and effective fat-loss
    · Increased vascularity and pump
    · Enhanced protein synthesis and elevated testosterone production
    · Modulation of estrogen and cortisol levels
    · Improved sexual performance

    Serving size: 1 cap/60caps per bottle
    750mg per (1) capsule

    N-Acetyl-Tyrosine
    Icariin
    Caffeine
    1,3 Dimethylamylamine
    N-Methyl-Beta-Methylphenylethylamine HCL
    Methyl-synephrine

    Engineered to unleash previously unknown levels of synergy, Phenadrine’s unsurpassed actives, including the novel and single most effective designer fat-loss compound, N-Methyl-Beta-Methylphenylethylamine HCL, collectively yield a new standard-setting advanced pharmaceutical-grade lipolytic stimulant and intense workout initiator. The matrix consists of:

  19. N-Acetyl L-Tyrosine
    N-Acetyl-Tyrosine (NAT) is an acetylated form of the essential amino acid, L-Tyrosine. NAT is more water soluble, and is therefore, a rapidly absorbed and more bio-available form than pure L-Tyrosine. L-Tyrosine modulates the synthesis of cortisol and thyroid hormones, as well as that of neurotransmitter catecholamines such norepinephrine (noradrenaline), epinephrine (adrenaline) and dopamine, that are depleted by stress. So, NAT supplementation reduces the impact of stress and fatigue and elevates cognitive performance. The neurotransmitter-stimulation action of NAT further synchronizes with similar synergistic action from 1,3-Dimetylamylamine and caffeine (caffeine stimulates release of catecholamines and NAT modulates their synthesis), leading to enhanced thermogenesis and lipolysis. Furthermore, by modulating thyroid hormones, NAT supports optimised base metabolic rate, promotes protein synthesis and glucose metabolism, enhances lipid metabolism by increasing adipose tissue sensitivity to hormones that modulate fat breakdown. As is well known, even a slight increase in active thyroid-hormone levels can produce a dramatic improvement in metabolism, energy levels, and mental attitude. Besides, NAT’s cortisol-modulating impact supports reduced fatigue, better recovery, and reduced adipose storage.

    Icariin
    An epimedium flavonoid and testosterone mimetic, icariin is a natural anabolic that possesses a variety of unique pharmacological actions in the body. It plays an important role in modulating nitric oxide levels by inhibiting an important enzyme, phosphodiesterase type 5 (PDE-5), that breaks down another enzyme, 3’,5’-cyclic Guanosine Monophosphate (cGMP). cGMP signals the smooth muscles to relax, enhancing blood flow. So, PDE-5 inhibition prolongs the action of cGMP, making possible the flooding of skeletal muscle tissue with nutrient-rich blood and oxygen, leading to improved muscle contraction, intense pump and vascularity, as well as promoting an environment conducive to anabolism. This PDE-5 inhibition is also the mechanism behind icariin’s dramatic improvement in sexual function in users. Furthermore, icariin, like testosterone, competes with glucocorticoids for receptor-site binding. By blocking glucocorticoids from binding to cortisol receptor sites, icariin inhibits cortisol action. This leads to an increase in the testosterone:cortisol ratio, triggering enhanced protein synthesis and anabolism. Furthermore, icariin produces a boost in cAMP levels, demonstrates estrogen-modulation properties, stimulates prolactin inhibition (via its action on dopamine receptors, thereby triggering an increased testosterone production), and promotes increased production of luteinizing hormone. Net, the cAMP elevation, selective cGMP inhibition, glucocorticoid antagonism, and estrogen modulation, all combine to improve the testosterone:cortisol and testosterone:estrogen ratios. Furthermore, via its function as an important acetylcholinesterase inhibitor, icariin boosts levels of the neurotransmitter, acetylcholine. This inhibition drives movement and promotes stronger muscle contractions, and a dense skeletal muscle structure.

    Caffeine
    Caffeine, a methylxanthine and popular stimulant, not only possesses lipolytic and appetite suppressant properties, but also helps to enhance endurance and extent the effect of other stimulants. As a CNS stimulant, caffeine works as an adenosine A1 and A2A receptor antagonist. This is significant because adenosine modulates the action of neurotransmitters such as dopamine, norepinephrine, and acetylcholine. Adenosine blocks the activity of excitatory neurotransmitters, creating a tatigue and a feeling of apathy. By antagonizing adenosine, caffeine stimulates nerve-cell activity, creating enhanced alertness and clarity. Furthermore, caffeine inhibits the enzyme, phosphodiesterase (PDE), that breaks down cAMP. This PDE inhibition leads to sustained cAMP activity and boosting norepinephrine, thereby up-regulating thermogenesis and lipolysis. These pathways ensure caffeine traces a synergistic action with 1,3-Dimethylamylamine and other agents in Phenedrine, creating an optimally fuelled fat-burning furnace in your body.

    Something else: Two enzymes, arginase and nitric oxide synthase compete against each other for the nitric-oxide metabolic pathway. The enzyme arginase converts arginine to ornithine and urea. Nitric oxide synthase converts arginine to nitric oxide, the potent vasodilator. A higher expression of the arginase enzyme leads to higher ornithine production, but less nitric oxide production. Now enters caffeine (methylxanthine caffeine). Caffeine inhibits arginase activity. It does this by inhibiting the so-called adenosine receptors, leading to higher levels of free adenosine. Now, adenosine, adenine, inosine, and uric acid, are known to be competitive arginase inhibitors. Furthermore, caffeine and caffeine-related compounds, also produce arginase inhibition by raising norepinephrine and cAMP. The caffeine-triggered arginase inhibition produces an elevated expression of the nitric-oxide synthase enzyme. This means even more nitric oxide is made available, leading to stronger vasodilation (and pump).

    1,3-Dimethylamylamine
    Also known as Geranamine, 1,3-Dimethylamylamine, a derivative of geranium oil, possesses a pharmacological activity similar to that of epinephrine (adrenaline), the body’s endogenous chemical messenger. As a potent fat burner, 1,3-Dimethylamylamine activates an enzyme, adenylate cyclase, that elevates cyclic adenosine monophosphate (cAMP) in cells, triggering fat metabolism. This is also one of the chemical pathways employed by ephedrine to potentiate fat burning. Furthermore, 1,3-Dimethylamylamine demonstrates potent central-nervous system (CNS) stimulation, leading to enhanced energy and physical performance, heightened focus and concentration, enabling the user to achieve a previously unknown intensity during training. The user will experience a significant elevation in energy levels without the usual crash common with many other stimulants.
    1,3-Dimethylamylamine is often combined with caffeine to further consolidate the heightened energy, intense concentration and focus, as well as euphoric feelings.

    N-Methyl-Beta-Methylphenylethylamine HCL
    This is a truly unique and novel compound, and one of compounds that sets Phenadrine apart from competition. Chances are you are familiar with the pharmacological pathways of Beta-Phenylethylamine (PEA). You may also be familiar with N-Methyl-Beta-Phenylethylamine HCL. Yet, do not confuse N-Methyl-Beta-Phenylethylamine HCL with our much more potent agent, N-Methyl-Beta-Methylphenylethylamine HCL with several methyl groups that render it super stable and remorselessly effective. This novel agent works! That simple!
    But why are PEA and its molecular derivatives even important for fat loss?

    A remarkable compound, even in its pure form, Beta-Phenylethylamine (PEA), a catecholamine precursor and nutrient found in chocolate, is known to be a very clean stimulant with the remarkable ability to achieve central-nervous-system stimulation without producing nervousness or the jittery feeling associated with other stimulants. Like norepinephrine, the body’s most potent endogenous fat-burning hormone, PEA acts on alpha-receptors in the brain, triggering the release of the “feel-good” hormone, dopamine (3,4-dihydroxy-phenethylamine) in neural cells. PEA is also responsible for chocolate’s effect on mood, sense of satiety, reduced food cravings, mild euphoria, as well as increased metabolic rate (by modulating thyroid function). Also known as a neuromodulator, PEA promotes mental alertness, focus and concentration. By regulating catecholamines such as epinephrine (adrenaline) and norepinephrine (noradrenaline) that act on hormone-sensitive lipase, the rate-limiting enzyme in the mobilization of fatty tissue from storage cites, PEA elevates the metabolic rate, ultimately leading to increased fat burning. Unfortunately, PEA is rapidly metabolised in the body by type B monoamine oxidase and has a limited ability to cross the blood-brain barrier, thus preventing it from unleashing its full effects. The challenge was to obtain a form of PEA with a type B monoamine-oxidase inhibitor property. N-Methyl-Beta-Phenylethylamine HCL is an N-Methyl derivative of Beta-Phenylethylamine. This methylated form of PEA is dramatically more potent than pure PEA, and takes PEA’s CNS stimulation and fat-burning several notches higher. While we could have used this compound, we decided to aim still higher. Now enters N-Methyl-Beta-Methylphenylethylamine HCL. This novel and carefully engineered unique agent represents the most potent form of PEA ever developed. It is not an N-Methyl derivative of N-Methyl-Beta-Phenylethylamine HCL, rather an N-Methyl derivative of methylated Beta-Phenylethylamine HCL! It is like “double methylation”! Such compounds do not come more potent than this! Technically speaking, we astronomically boosted the pharmacokinetic value of PEA! This “double methylated” form unites the finest properties of PEA such as easily crossing the blood-brain barrier to elevate feelings of euphoria, intensifying fat-burning due to optimised beta-receptor agonism while demonstrating unprecedented stability to B monoamine oxidation, implying a longer-lasting and significantly more intensive overall action. Our N-Methyl-Beta-Methylphenylethylamine HCL is by far the most potent designer fat-loss agent ever developed, and you would not find it in many of fat-loss products around. It elevates the potency of our synergistic blend to never-before-seen levels! You will be convinced!

  20. Methyl-Synephrine HCL
    Do not mistake this compound for pure synephrine! It is light years away, in terms of superiority. If synephrine worked for you, Methyl-Synephrine HCL will blow your mind! First, back to the basics. What is synephrine? Obtained from the citrus tree known as Citrus aurantium or Bitter Orange, synephrine is an active alkaloid with structural similarities to epinephrine and norepinephrine. Synephrine’s claimed thermogenic, lipolytic, and appetite suppression effects are derived from its alpha-adrenergic properties that provoke the activation of beta-3 receptors. The claim that synephrine’s beta-3-receptor binding triggers lipolysis at very high dosages appeared to based on Carpene et al (1999). Subsequent studies, e.g., Larsen et al (2002) and Bent et al (2004), however, demonstrated that beta-3-receptor agonists appeared to have dramatically less lipolytic action in human fat cells, compared to animal fat cells.
    The picture, however, appears to change significantly with the use of a recently developed unique form of synephrine referred to as Methyl Synephrine. Using the methylated form of synephrine (derived by substituting or attaching a methyl group to different molecules) dramatically alters its pharmacological pathway, and appears to make the compound significantly more effective than pure synephrine. Methyl synephrine is an adrenergic amine that has unique and amplified pharmacological effects by acting, not only as a beta-3 receptor agonist, but also as an alpha-1 adrenergic agonist. This difference is significant, because pure synephrine is postulated to act as a beta-3-receptor agonist only. This means methyl synephrine works by significantly up-regulating the metabolic rate and enhancing fat metabolism and thermogenesis, while only mildly stimulating the central nervous system without adversely impacting blood pressure and heart function, unlike beta-2 receptor agonists such as ephedrine that trigger anxiety and irregular heartbeat. As a beta-3-receptor agonist, methyl synephrine up-regulates the action of epinephrine and norepinephrine (the most potent endogenous fat-burning agent around) within adipose tissue, leading to significant lipolysis. So methyl synephrine not only up-regulates fat breakdown (as a beta-3 receptor agonist), but also profoundly enhances the burning of released body fat for energy (as an alpha-1 agonist). Double punch!

    As you can see, Phenadrine is no regular “kitchen-sink” formula. Rather, it represents a new standard in “double-punch” products that effectively combine intense-workout potentiating compounds with advanced lipolytic and thermogenic agents to deliver the performance you are looking for, and that we are known for. Our unique matrix of selected agents is delivered in pharmaceutical-grade purity and in potent per-dose-amounts that work every time. If you are looking for an effective double-punch product beyond the reach of competition, your search stops at Phenadrine! Advanced Lipolytic Stimulant. Intense Workout Potentiator.


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    Cox GR, Desbrow B, Montgomery PG, Anderson ME, Bruce CR, Macrides TA, Martin DT, Moquin A, Roberts A, Hawley JA, Burke LM. Effect of different protocols of caffeine intake on metabolism and endurance performance. J Appl Physiol. 2002 Sep;93(3):990-9.

    Davis JM, Zhao Z, Stock HS, Mehl KA, Buggy J, Hand GA. Central nervous system effects of caffeine and adenosine on fatigue. Am J Physiol Regul Integr Comp Physiol. 2003 Feb;284(2):R399-404. Epub 2002 Oct 24.

    Dollins AB, Krock LP, Storm WF, Wurtman RJ, Lieberman HR. L-tyrosine ameliorates some effects of lower body negative pressure stress. Physiol Behav. 1995 Feb;57(2):223-30.

    Dourish CT, Greenshaw AJ, Boulton AA. Deutrium substitution enhances the effects of b-phenylethylamine on spontaneous motor activity in the rat. Pharmacol. Biochem. Behav. 1983, 19: 471-475.

    Dourish CT, Boulton AA. The effects of acute and chronic administration of beta-phenylethylamine on food intake and body weight in rats. Prog Neuropsychopharmacol. 1981, 5(4): 411-414.

    Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 2006 Feb;7(1):79-88.

    Grimsby J, Toth M, Chen K, Kumazawa T, Klaidman L, Adams JD, Karoum F, Gal J, Shih JC. Increased stress response and beta-phenylethylamine in MAOB-deficient mice. Nat Genet. 1997, 17(2): 206-210.

    Hull EM, Muschamp JW, Sato S. Dopamine and serotonin: influences on male sexual behavior. Physiol Behav. 2004 Nitric oxidev 15;83(2):291-307
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  21. great write up. looks good.
    cant wait to try this

  22. Quote Originally Posted by bioman View Post
    Age: 36

    Height/Weight: 5'10" currently 168.

    Short Term Goal: Recomp and bulk back up to my former weight of 187 after almost a year off. Also seeking a stim that can aid with the sort of work I do..long days hiking around in rough terrain.

    Years of training: 15

    Prior stim use: ECA, Yohimbine/Yohimbe, geranium oil, Drive, RPM, Fyre, Sulbutiamine, PEA, L-Tyrosine, ALCAR, PLCAR, Choline, and lots of caffiene.

    Current Supplements: Multi vitamin/minerals, Poseidon, fish oil and Relora.

    Too many reviews to dredge up.

    If the results are great and I can keep diet/training on track the entire time, then I will post photos.
    Very nice application!!!!!!!!

  23. Just for clarification, APS - I applied to log this in the other thread http://anabolicminds.com/forum/aps-n...ml#post1512001
    - I can transfer my app to this thread if this is where you want them.
    Bulk Performance Solutions
    --No Proprietary Blends, All Performance--

    ***NOW @ NP***
  24. I am intrested in this Test


    This will be my first time ever for presenting myself for any kind of trial testing

    Here are some details for me please let me know how will you contact me or what will be the process

    Serving size: 1 cap/60caps per bottle
    750mg per (1) capsule

    N-acetyl-Tyrosine
    Icariin
    Caffeine
    1,3 dimethylamylamine
    N-methyl-beta-methylphenylethylamine hcl
    Methyl-synephrine

    Age: 36 Years

    Height/Weight: 5.7"

    Short term goal (cut, bulk, recomp, etc): Cut (lose Weight)

    How long have you been training: 2 Months

    Prior supplement use: None

    Current supplements: Levithian Reloaded

    ANY medication (OTC/Prescription): None

    LINKS to past logs and/or reviews of ANY products: N/A

    Will you post progress or before/after photos? Yes for Sure
  25. I am also interested in the Test


    Here are my details. Feel free to contact me about this trial.

    Age: 31 Years

    Height/Weight: 5' 11"

    Short term goal (cut, bulk, recomp, etc): Cut

    How long have you been training: 1 year

    Prior supplement use: None

    Current supplements: None

    ANY medication (OTC/Prescription): None

    LINKS to past logs and/or reviews of ANY products: none

    Will you post progress or before/after photos? Yes
  •   

      
     

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