Feedback from a customer using Epistane to help reduce their gyno.

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  1. Quote Originally Posted by futurepilot View Post
    thanks for all your help
    come on though, Ive answered your many questions its a proven compound and the Anti-E effects are quite apparent and documented as well and you want me to spoon feed you studies I have no access to or you wont be pleased....

    Ive given you a considerable amount of info on Epistane and its parent compound Thioderon (Mepitiostane) and if you REALLY have to have that study or further info you can use your god given abilities to do so and search.

    I am a helpful individual but cant and wont help those who arent willing to help themselves.

    good luck in your search pilot.


  2. kinda funny the extensiveness of most wiki profiles on subjects BUT the only damn thing they have on Mepitiostane is this.

    http://en.wikipedia.org/wiki/Mepitiostane
    Mepitiostane (INN) is an antiestrogen.
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  3. heres this from steroid Guru, Dr. Seth Elliot

    http://www.anabolicextreme.com/anabo...allyactive.htm
    What the…? I realize that most of you have never heard of Epitiostanol as it is a relatively obscure steroid used for breast cancer that is only available in Japan. Again you might say, “How does a drug used for breast cancer work for us extreme fitness types?” Well, Epitiostanol was actually developed back in the 1960’s and has an extremely good anabolic/androgenic ratio. This means that it causes a whole host of positive effects in the body with minimal negative androgenic effects. The reason it was used for breast cancer is that it was shown to exert a potent anti-estrogenic effect which halted the progression of estrogen-stimulated cancers. What wonderful characteristics to have in a steroid! Great muscle growth with small androgenic phenomenon with no estrogenic problems like gyno…sounds like the perfect steroid!

  4. on a template of Sex hormones in the human body this was listed...

    notice the ONLY anti estrogen found in the human body...

    http://en.wikipedia.org/wiki/Template:Sex_hormones

  5. heres a facts page on tamoxifen citrate an known SERM and anti-E... just so happens they also list an entire list of OTHER anti E compounds... guess what just so happens to be on that list???

    http://chemicalland21.com/lifescienc...%20CITRATE.htm
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  6. Now remember Epistane is merely a methylated version of Mepitiostane in order to increase its oral bioavailability also allowing it to be sold as a designer "supplement".

    I hope this has been adequate enough to fit your fancy pilot... Im done doing this now, any further proof on this subject will have to be provided on your own or by someone else as I think the facts are quite clear as to what this compound IS and why we market it as we do.

    Thanks for your interest.

  7. OK one more... I cant resist this one... a straight out study using a STEROID to decrease the size of a tumor of the mammary gland... which is what Tamox and other anti E's used by body builders for gyno reduction are intended for as well, thus one can conclude the same could be said of these STEROIDS in their use for reduction in gyno, a very similar growth to mammary gland cancer if you will.....

    wonder what STEROID it just so happened to be?

    http://www.cs.cmu.edu/~nmramesh/canc...nk_0_docs.html
    13. DOCID:3890 SCORE: 0.00330634829304048
    DOCNO: 922732
    OWNER: NLM
    STATUS: MEDLINE
    DESCRIPTOR: Antineoplastic Agents
    DESCRIPTOR: Pregnancy, Animal
    QUALIFIER: therapeutic use
    QUALIFIER: therapeutic use
    QUALIFIER: drug therapy
    AUTHOR: A Matsuzawa A
    AUTHOR: T Yamamoto T
    PUBTYPE: Journal Article
    JOURNALTITLE: Cancer research.
    COUNTRY: UNITED STATES
    TITLE: Antitumor effect of two oral steroids, mepitiostane and fluoxymesterone, on a pregnancy-dependent mouse mammary tumor (TPDMT-4).
    PUBDATE: 19771201
    Pregnancy-dependent TPDMT-4 mammary tumors, characterized by requiring estrogen, progesterone, and pituitary hormones for growth, grew continuously in female DDD mice carrying pituitary isografts. The experimental model was used to investigate the antitumor effects of two p.o. steroids, mepitiostane and fluoxymesterone. When tumors implanted with pituitary isografts into the fat-pad reached palpable size, animals received 6 doses/week of 0.1, 0.3, 1.0, and 3.0 mg of either steroid intragastrically. Mepitiostane significantly suppressed tumor growth with regression in 25 and 29 percent of animals at 1.0 and 3.0 mg, respectively, but had no inhibitory effects at other doses. Fluoxymesterone retarted tumor growth during the first week of treatment at 3.0 mg but finally had no inhibitory effects at any doses. Under similar conditions ovariectomy caused tumor regression immediately, and epitiostanol, the parent steroid of mepitiostane, significantly suppressed tumor growth when given in 3 injections/week of 0.5 mg s.c. Tumous had papillary structures and almost lacked secretory activity.
  8. Thumbs down


    Why don't you guys just ask dsade whether this compound will get rid of gyno since he brought it to the market?

    I'll tell you one thing, it does not.

  9. Quote Originally Posted by Machine Mind View Post
    Why don't you guys just ask dsade whether this compound will get rid of gyno since he brought it to the market?

    I'll tell you one thing, it does not.
    There MAY be SOME cases where it does not appear to be working. Just as the studies never stated that ALL estrogen-dependent tumors' growth was halted by the addition of mepitiostanol.

    Some people have used letrozole and raloxifene and it didn't work either. Does that mean those compounds have no effect on breast tissue in males?

    Since when is a n=1 study worth the paper it's printed on??? :donut:

  10. Quote Originally Posted by Machine Mind View Post
    Why don't you guys just ask dsade whether this compound will get rid of gyno since he brought it to the market?

    I'll tell you one thing, it does not.
    LOL not this debate.... greeeeeaaaaattt....

    Well you go ahead and release a product a week or so following another without first researching the compound, sourcing it, shipping it and capping it, making up a design label and bottling agreement for the product and tell me you got the idea from that product released a week ago.

    Not gonna happen brother. It just so happens that they both intended on bringing this compound to market at the same time AND if Dsade chooses not to exploit its inherent anti estrogen capabilities then so be it, we did and it doesnt change the facts ONE BIT.

    This is no way talking bad about Dsade OR RPN as I have great respect for both, just stating the facts which you sir obviously have mixed up and/or are far too ignorant to read my previous posts on the subject.

    I personally would look at the facts and studies on a compound and not how its marketed to decide what it can and cant do.

  11. I'm not trying to start anything regarding the RPN comment.

    I'm just saying Epistane/Havoc/clones are NOT mepitiostanol and to regard & advertise them as such is irresponsible.

  12. Quote Originally Posted by Machine Mind View Post
    I'm not trying to start anything regarding the RPN comment.

    I'm just saying Epistane/Havoc/clones are NOT mepitiostanol and to regard & advertise them as such is irresponsible.
    You realize that mepitiostane is a methoxy ether attached to plain old epitiostanol, where as Epistane is a 17aa methylated version of the same epitiostanol. Two different ways of increasing the absorption of the parent compound, both carry the inherent properties of that parent compound as well.

    So to ignore the fact that it carries these properties would be foolish and to use those studies to prove such is anything but irresponsible.

    As stated by Grunt, they even state in the studies that its not perfect, does not work EVERY TIME in stopping or reversing growth, is dose dependent and we have seen real world results of this doing EXACTLY what its stated it can do. I myself personally saw these results in an unsponsored log WITH pictures for everyone to see BEFORE I was ever even considered for a rep position for IBE. This gentlemen that PM'd lake obviously had a similar experience along with many many others seeing these type of results.

    SO to sell it as an end all cure WOULD be foolish BUT thats not what we have done or are doing, we are merely stating this is a property of this compound and one MAY see the same results if desired with a proper dosing protocol.

    So tell me how is this anymore irresponsible to tout as an anti estrogen then it is for any of say the 6-OXO, ATD or 6-Bromo sellers to use a STEROIDAL AI as a PCT supplement when if dosed high enough (very touchy at that from rec dose to over dose) can actually become suppresive itself and also cause a nasty rebound in Estrogen upon cessation if one uses aggressive dosing thinking that more is better?

    It isnt.

  13. Quote Originally Posted by poopypants View Post
    You realize that mepitiostane is a methoxy ether attached to plain old epitiostanol, where as Epistane is a 17aa methylated version of the same epitiostanol. Two different ways of increasing the absorption of the parent compound, both carry the inherent properties of that parent compound as well.

    So to ignore the fact that it carries these properties would be foolish and to use those studies to prove such is anything but irresponsible.

    As stated by Grunt, they even state in the studies that its not perfect, does not work EVERY TIME in stopping or reversing growth, is dose dependent and we have seen real world results of this doing EXACTLY what its stated it can do. I myself personally saw these results in an unsponsored log WITH pictures for everyone to see BEFORE I was ever even considered for a rep position for IBE. This gentlemen that PM'd lake obviously had a similar experience along with many many others seeing these type of results.

    SO to sell it as an end all cure WOULD be foolish BUT thats not what we have done or are doing, we are merely stating this is a property of this compound and one MAY see the same results if desired with a proper dosing protocol.

    So tell me how is this anymore irresponsible to tout as an anti estrogen then it is for any of say the 6-OXO, ATD or 6-Bromo sellers to use a STEROIDAL AI as a PCT supplement when if dosed high enough (very touchy at that from rec dose to over dose) can actually become suppresive itself and also cause a nasty rebound in Estrogen upon cessation if one uses aggressive dosing thinking that more is better?

    It isnt.
    **SINGING**

    You took the words right out of my mouth,
    Oh it must have been when you were kissing....
    ... ummm....
    ...Lake?

    Adams
    The Historic PES Legend

  14. lol uuuuur weeeeeeerd.
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