I have heard about this as well. Not sure the rationale given, but a much shorter life expectancy. Kinda curious what role it plays on stress for the heart as well
I don't know about
much shorter. I've heard that there is a possibility for a shorter life expectancy, but I don't believe this is always the case. Muscle cramping seems to be a big issue with animals that have been studied that have the myostatin mutation.
Belgian Blue cattle have this mutation and are specifically bred with two mutated genes in order to get larger quantities of lean meat.
You guys ever hear of Wendy the Whippet?
Whippets are a breed of dog that resemble small greyhounds and are bred for speed. National Human Genome Research Institute also did a study on these animals. What scientists have begun to notice is that dogs with one mutated copy are more muscular and significantly leaner, but are also much faster than dogs without a mutated copy. These are the prize whippets that breeders strive for. Whippets that ended up with two mutated copies (biology - we have two copies of each gene; one from the mother and one from the father) were the double-muscled ones. They are HUGE, lean, and not nearly as fast. They're known as "bully whippets". I want one.
genome.gov | 2007 News Features: NHGRI Researchers Explore Genetics of Canine Speed
Meet the Incredible Hulk of Hounds | the Daily Mail
Big Wendy the muscular whippet
I believe the German kid is said to have one mutated copy, and there's another kid around I was reading about with one mutated copy of his myostatin gene as well. His name is Liam Hoekstra, and at 19 months old they say he's fast as the wind, has the agility of a cat, six pack abs, and has 40% more muscle mass than normal kids his age. The article also said his metabolism is through the roof and he gets hungry for a full meal every hour.
globeandmail.com: Dad sees a future football star
Definitely some interesting stuff. I'm always trying to read up for updates on myostatin research. Highly intriguing!