[Pound4Pound]

This article will discuss in two parts the pharmacology and mechanism of action of modafinil, followed by a third section on Therapeutic Use. Modafinil is a unique psychostimulant drug that acts stereotypically through dopaminergic and adrenergic neurons, but also acts selectively on regions of the brain involved in the regulation of wakefulness and arousal. The stimulation of hypothalamic histamine levels and interaction with orexin receptors in promoting wakefulness render modafinil a relatively unique drug in its class – stimulating research efforts into understanding how modafinil works on a biochemical and neurological level.

Chemically Correct: Modafinil


Chemically Correct: Modafinil Part II - Pharmacology

[Force of Green]

Originally Posted by Pound4Pound

This article will discuss in two parts the pharmacology and mechanism of action of modafinil, followed by a third section on Therapeutic Use. Modafinil is a unique psychostimulant drug that acts stereotypically through dopaminergic and adrenergic neurons, but also acts selectively on regions of the brain involved in the regulation of wakefulness and arousal. The stimulation of hypothalamic histamine levels and interaction with orexin receptors in promoting wakefulness render modafinil a relatively unique drug in its class – stimulating research efforts into understanding how modafinil works on a biochemical and neurological level.

Chemically Correct: Modafinil

Why is this in the Avant Labs forum? Are they coming out with a product similar to modafinil/adrafinil? I think it's a lame compound for attention, but maybe it's better for narcoleptics.

[dsade]

Originally Posted by Force of Green

Why is this in the Avant Labs forum? Are they coming out with a product similar to modafinil/adrafinil? I think it's a lame compound for attention, but maybe it's better for narcoleptics.

Avant Labs started Mind and Muscle magazine, and is based on thorough scientific inquiry (hence the extremely high quality of their supplements) and hypothetical discussion/analysis of mechanism.

It makes sense to link from this subforum.

[Force of Green]

Originally Posted by dsade

Avant Labs started Mind and Muscle magazine, and is based on thorough scientific inquiry (hence the extremely high quality of their supplements) and hypothetical discussion/analysis of mechanism.

It makes sense to link from this subforum.

Ahhh... I see. Cool beans.

Yeah, also just because I'm not much of a fan of modafinil (Provigil) doesn't mean it's not a good compound... I used it for purposes that are still being researched (amphetamine/methamphetamine withdrawal).

[rpen22]

Originally Posted by dsade

Avant Labs started Mind and Muscle magazine, and is based on thorough scientific inquiry (hence the extremely high quality of their supplements) and hypothetical discussion/analysis of mechanism.

It makes sense to link from this subforum.

Word.

P4P is like the M&M rep and posts links to the new articles here and on BB.com, I believe; maybe others as well.

[diminuendo]

I miss the old avant board. I think it would be hard to find such a small group anywhere with as many IQ points.

[Pound4Pound]

Originally Posted by rpen22

Word.

P4P is like the M&M rep and posts links to the new articles here and on BB.com, I believe; maybe others as well.

Yup, there are a couple others as well.

[Pound4Pound]

Part II is up.

Chemically Correct: Modafinil Part II - Pharmacology