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Old 01-16-2008, 09:42 AM   #31
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I think i'm going to add it to my lipo-u bulk I got from np and added RK to already, and then use napalm straight for the inbetween weeks. Does that sound like a winner? I have about 6-7 oz of the lipo u left, and around 40ml of 200mcg/ml clen.
 



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Old 01-16-2008, 10:04 AM   #32
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So in theory, it could help out by making some clen in 15ml bottles at about 400mcg/ml (giving the suggested 6000mcg total) and using it with the Napalm to prevent overfilling.
 
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Old 01-16-2008, 02:29 PM   #33
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Quote:
Originally Posted by N4cer
So in theory, it could help out by making some clen in 15ml bottles at about 400mcg/ml (giving the suggested 6000mcg total) and using it with the Napalm to prevent overfilling.
Indeed the volume can be an issue when dealing with the liquid forms of Clen. If powder cannot be obtained, your best option is to purchase two bottles of Napalm (something we suggest regardless for cycling purposes). Once you've used about a 1/3-1/2 of the first bottle it can be enhanced with ease and you're off to the races.

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Old 01-16-2008, 02:38 PM   #34
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Yes, like SP mentioned, two bottles is never a bad idea. You can also draw out 60ml and add 15ml (100mcg/ml). Those 75ml will last you 9.5 days at full dose (4ml x 2). Then finish up with the balance of 60ml straight Napalm at full dose (3ml x 2) for the next 10 days.
 
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Old 01-18-2008, 12:10 AM   #35
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Its tricky with one bottle and liquid, but feasible if you've got a chemistry set lying around and some decent glassware.
 



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Old 01-20-2008, 09:08 PM   #36
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Will liquid albuterol act as a good subsititute for clen?
 
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Old 01-21-2008, 12:39 PM   #37
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Quote:
Originally Posted by eagleba
Will liquid albuterol act as a good subsititute for clen?
As it is comparable in both structure and molecular weight, I would make the educated assumption that they can be used interchangeably. Have to keep me updated on the progress, it will be interesting to note if your improvements are more significant than your cohort using clen.
 



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Old 01-21-2008, 01:30 PM   #38
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as an interesting side thought on this, would you be able to alternate bottles of clen spiked and albuterol spiked to avoid downregulation?
 



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Old 01-21-2008, 02:07 PM   #39
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Albuterol's short duration of action will demand more frequent dosing than clen, regardless of route of administration.
 
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Old 01-21-2008, 03:49 PM   #40
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Quote:
Originally Posted by N4cer
Albuterol's short duration of action will demand more frequent dosing than clen, regardless of route of administration.
Interesting comment. Are you making this assumption based on typical methods of delivery? Keep in mind that the transdermal delivery via Napalm, Lipoderm or other topicals, avoids typical metabolism associated with drug use.

That said, am I unaware of an extracellular removal mechanism unique to albuterol?
 



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Old 01-21-2008, 04:01 PM   #41
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I'm saying albuterol has a shorter duration of activity than clen. Period. If using the same route of administration for both, regardless of what route that is, albuterol is a shorter acting compound than clenbuterol.
 
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Old 01-21-2008, 04:59 PM   #42
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Albuterol
Chemical Name: Albuterol Sulfate
Drug Class: Beta-Agonist
Albuterol is very closely related to Clenbuterol (often simply called “Clen”), which has been a drug athletes have been using for literally decades to lose fat. Although it’s typically thought of as only a shorter acting version of Clenbuterol, that’s not 100% correct, and Albuterol actually has some benefits that Clen doesn’tJust like Clen, Albuterol binds to the beta 2 adrenergic receptors. Beta 2 receptor stimulation is a very potent mechanism for initiating fat loss. Stimulating the beta-2 receptors found in fat cells activates hormone sensitive lipase, to break up stored fat into free fatty acids which are then used as fuel by the body (1). Once those fatty acids are broken up, Albuterol then has the added effect of elevating your metabolism, which helps you use the free fatty acids that it has broken up. It’s a very potent fat burner, as a result of both being able to break up stored fat and make it available as energy, as well as increasing the rate at which this energy is used.

Interestingly, while Clenbuterol increases both muscle size and strength in animal studies (2), the same thing isn’t necessarily true in humans, and if it is, actual studies proving so are nearly impossible to find. It’s suspected to possibly do this, but there’s really no hard evidence of it. And since it’s not approved by the FDA for use in humans, non-anecdotal data proving that Clen actually builds muscle or increases performance is scarce. Since it’s approved by the FDA for use in asthmatics, studies on humans and Albuterol, regarding exercise performance are more plentiful. In multiple studies, it has been suggested strongly that it increases strength as well as endurance in humans (3,4). Clen, on the other hand, has anecdotally been reported to reduce endurance in athletes who use it.

In addition, Albuterol may even help the lipid profile (cholesterol)(5), which is definitely something that steroid using athletes may want to consider, when deciding whether or not to include Albuterol in a cutting cycle. In fact, a small dose of it might be useful on nearly any cycle, because of this characteristic.

The main difference between Albuterol and Clen is that Albuterol has a significantly shorter half life than Clen. If Clenbuterol happens to give you insomnia, then Albuterol is a much better alternative, because it’s not going to build up in your system to the same degree that Clen can.

I’m typically much more confident recommending Albuterol to athletes instead of Clen, because stimulant induced anxiety and insomnia seem to be much less likely. Also, due to the shorter half life, there’s probably a much lower level of beta-2 receptor downgrade, but the trade off is more frequent dosing. Two to four milligrams, three to four times a day is usually sufficient for an anabolic as well as fat burning effect.

References:

1. Effect of beta1- and beta2-adrenergic stimulation on energy expenditure, substrate oxidation, and UCP3 expression in humans.

2. Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E775-82. Epub 2003 Jun 24.

3. J Appl Physiol. 2001 Nov;91(5):2064-70

4. Med Sci Sports Exerc. 2000 Jul;32(7):1300-6. Effect of salbutamol on muscle strength and endurance performance in nonasthmatic men. van Baak MA, Mayer LH, Kempinski RE, Hartgens F.

5. Aviat Space Environ Med. 2004 Jun;75(6):505-11 Albuterol helps resistance exercise attenuate unloading-induced knee extensor losses. Caruso JF, Hamill JL, Yamauchi M, Mercado DR, Cook TD, Keller CP, Montgomery AG, Elias J.

6. Metabolism. 1996 Jun;45(6):712-7 Effects of oral albuterol on serum lipids and carbohydrate metabolism in healthy men. Maki KC, Skorodin MS, Jessen JH, Laghi F.
 
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Old 01-21-2008, 06:57 PM   #43
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Nice post B Fiddy!
 



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Old 01-21-2008, 07:02 PM   #44
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hmm albuterol FTW it would seem in a transdermal.
 



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Old 01-21-2008, 08:49 PM   #45
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