Green Tea in HGH UP
- 09-19-2011, 09:12 PM
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- 09-20-2011, 09:53 AM
09-20-2011, 01:33 PM
I saw some info on green tea in terms of messing with testosterone levels. Nothing I've witnessed taking it since I cruise all the time. But something to note for others taking it
09-20-2011, 06:03 PM
where did you see that
09-20-2011, 11:16 PM
But I dont think there is much we can really take away from it. They incubated non-human leydig cells with green tea extract as well as with a direct precursor to testosterone along with the necessary enzymes and testosterone production did decrease.Green tea polyphenols inhibit testosterone production in rat Leydig cells.
This study investigated the acute effects of green tea extract (GTE) and its polyphenol constituents, (-)-epigallocatechin-3-gallate (EGCG) and (-)-epicatechin (EC), on basal and stimulated testosterone production by rat Leydig cells in vitro. Leydig cells purified in a Percoll gradient were incubated for 3 h with GTE, EGCG or EC and the testosterone precursor androstenedione, in the presence or absence of either protein kinase A (PKA) or protein kinase C (PKC) activators. The reversibility of the effect was studied by pretreating cells for 15 min with GTE or EGCG, allowing them to recover for 1 h and challenging them for 2 h with human chorionic gonadotropin (hCG), luteinizing hormone releasing hormone (LHRH), 22(R)-hydroxycholesterol or androstenedione. GTE and EGCG, but not EC, inhibited both basal and kinase-stimulated testosterone production. Under the pretreatment conditions, the inhibitory effect of the higher concentration of GTE/EGCG on hCG/LHRH-stimulated or 22(R)-hydroxycholesterol-induced testosterone production was maintained, whereas androstenedione-supported testosterone production returned to control levels. At the lower concentration of GTE/EGCG, the inhibitory effect of these polyphenols on 22(R)-hydroxycholesterol-supported testosterone production was reversed. The inhibitory effects of GTE may be explained by the action of its principal component, EGCG, and the presence of a gallate group in its structure seems important for its high efficacy in inhibiting testosterone production. The mechanisms underlying the effects of GTE and EGCG involve the inhibition of the PKA/PKC signalling pathways, as well as the inhibition of P450 side-chain cleavage enzyme and 17beta-hydroxysteroid dehydrogenase function.
HOWEVER, the problem with this is the test decrease was pretty dependent on the amount of EGCG exposure and this doesnt really translate well when we are talking about taking oral doses of green tea extract in humans.
We can not correlate the findings of incubated rat leydig cells to oral green tea human consumption.
The green tea in HGHup should not be a problem in my opinion
"The only good is knowledge and the only evil is ignorance." - Socrates
09-20-2011, 11:55 PM
HGHup has test boosting properties so even IF green tea would decrease your test a little bit, the other ingredients would cover that, although test boosting for HGHup isnt its MOA.
that being said, i was not saying you were wrong, just never heard of it before and wanted to see a study done on it. thanks josh
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