I have not heard of anything gyno related with Igf-2.... Are you using it as a standalone? Are you PCT'ing from a past cycle? It has L-dopa which is used to lower Prolactin levels, as for estrogen levels I don't see any ingredients that would have an impact on that. Safed musli can help to release testosterone... other than that I don't see any reason that Igf-2 would be the cause here. Can you give me somemore information on what you are currently taking, have taken recently?