A ? for PA "PROHORMONES, CONVERSION RATES AND BROSCIENTISTS" - AnabolicMinds.com

A ? for PA "PROHORMONES, CONVERSION RATES AND BROSCIENTISTS"

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    A ? for PA "PROHORMONES, CONVERSION RATES AND BROSCIENTISTS"


    You wrote an article in MD June 2009 in which you explained how to convert say Methyl-1, 4-Androstenediol to Methandrostenolone "see quoted text at bottom" Now what I am wondering is, are there any hormones out there on the market that could be fun and maybe still useful to convert that a home hobbyist could do as a home chemistry project? I think this idea sounds like a lot of fun but I would like to avoid the DEA so I am looking for a conversion to a non-scheduled substance.

    Also in the procedure you explained where it says "you must mix the slurry for several hours say 6-8" would a Pneumatic Paint Shaker be enough to "mix" as you stated?


    Quote Originally Posted by Patrick Arnold;
    No, the answer to the question I am talking about is not “Don’t pay her.” I am talking about making active anabolic steroids from readily available prohormones.
    Actually, this is not something I would normally write about, but I had writer’s block this month and John Romano said this sort of thing would be something he would
    be interested in reading. So I thought I would delve into it a little. I have to warn you though, unless you have a background in steroid chemistry, this is not gonna
    make much sense to you.
    As you know, prohormones are metabolic precursors to active hormones, which are converted
    through the action of enzymes in your body. But these same prohormones can also be converted to the active hormones synthetically— that is, by the use of chemicals in
    a lab. In
    particular, diols and diones can be made into their corresponding active hormones by procedures that are actually remarkably simple.

    Diols
    The most basic diol is 4-androstenediol. However, it is now illegal. There are still some diols
    out there, though. Here is a list containing 4-androstenediol and some other still legal diols.
    If you look closely, you will see that all these diols have double bonds in the first ring that are
    one carbon atom away from the 3-hydroxyl. The hydroxyl at carbon 17, however, does not have
    this feature. We can use this difference to our advantage and perform what is known as an
    ‘allylic oxidation.’Allylic oxidations can be done using a variety of different chemical reagents; however, activated manganese dioxide is the most convenient one to
    use. What this chemical
    does is oxidize the hydroxyl at carbon 3 to a ketone, while leaving the 17 beta-hydroxyl unaffected. This leaves you with the classic ‘3-one-17b-ol’ structure that
    most active anabolic steroids possess.

    The procedure is simple. You dissolve the steroid (let’s say 5 grams) in an appropriate organic solvent (let’s say 250cc of acetone) and then add about six times its
    weight in activated manganese dioxide. It is important that you use activated manganese dioxide because regular
    manganese dioxide won’t work. The activated manganese dioxide will not dissolve, but rather it will sink to the bottom. You must then mix the slurry for several hours
    (say 6-8 hours).

    After you are done, you filter off the manganese dioxide, or let it settle out and decant the clear layer. This clear layer will contain your active steroid in acetone
    and you can retrieve it either by slowly evaporating off the acetone, or by adding about five parts water and precipitating the steroid out. The precipitated steroid
    can then be filtered off and dried.

    Examples of this reaction are the conversion of 4-androstenediol to testosterone, the
    conversion of 17a-methyl-1,4-Androstadien-3b,17bdiol to dianabol, and the conversion of
    4-chloro-17a-methyl-androsta-1,4-dien-3b-17b-diol to oral Turinabol.
    Please don’t forget the fact that as soon as you are done with this chemical procedure, you have a controlled substance on your hand and you are therefore committing a
    felony. It is for this reason that I must remind you now that this is all being presented to you for purely informational and entertainment purposes.
    Next month I will continue the chemical information and entertainment by discussing the
    chemical conversion of diones."

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    yeah a pneumatic paint shaker would work. I should get one of those for my lab!
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    Quote Originally Posted by Patrick Arnold View Post
    yeah a pneumatic paint shaker would work. I should get one of those for my lab!
    I have found mine to be useful for many side projects any fun conversion ideas you could share? Hopefully non scheduled to non scheduled?

    Sent from my ADR6300 using Tapatalk 2
    ForeRunner Labs
    The Future of Human Performance
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    Quote Originally Posted by harbonah View Post
    You wrote an article in MD June 2009 in which you explained how to convert say Methyl-1, 4-Androstenediol to Methandrostenolone "see quoted text at bottom" Now what I am wondering is, are there any hormones out there on the market that could be fun and maybe still useful to convert that a home hobbyist could do as a home chemistry project? I think this idea sounds like a lot of fun but I would like to avoid the DEA so I am looking for a conversion to a non-scheduled substance.

    Also in the procedure you explained where it says "you must mix the slurry for several hours say 6-8" would a Pneumatic Paint Shaker be enough to "mix" as you stated?
    A magnetic stir plate and stirbar is a bit more standard equipment but this paint mixer mod is decent due to exposure of the heterogeneous reaction mixture. If it was homogeneous, just heat or just letting it sit would probably be fine but you may need to increase reaction temps.

    And make sure you activate MnO2 under heat (~140 *C) for at least a few hours and cool either under vacuum or in a dessicator.
    E-Pharm Nutrition Representative
    WARNING: I tend to speak my mind and will verbally assault you if you are a tool. My words do not necessarily represent the official opinion of E-Pharm, but most likely, they do.
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    Quote Originally Posted by Beejis60 View Post
    A magnetic stir plate and stirbar is a bit more standard equipment but this paint mixer mod is decent due to exposure of the heterogeneous reaction mixture. If it was homogeneous, just heat or just letting it sit would probably be fine but you may need to increase reaction temps..

    the MnO2 is pretty dense powder and sometimes stir bar stops stirring. a shaker would be nice
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    Quote Originally Posted by Patrick Arnold View Post
    the MnO2 is pretty dense powder and sometimes stir bar stops stirring. a shaker would be nice
    I've done a couple Gilman-Ganem oxidations with no problems... I also didn't use like 20eq nor made it balls concentrated either. I guess it can look like mud at times, so perhaps a shaker is fine and I'm sure it's a bit cheaper than a stir plate. Plus, I imagine doing this on a large scale, which will need quite a bit of torque from the stir plate that really doesn't exist...
    E-Pharm Nutrition Representative
    WARNING: I tend to speak my mind and will verbally assault you if you are a tool. My words do not necessarily represent the official opinion of E-Pharm, but most likely, they do.
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