Glucose Disposal Agents - Q&A with Dr. Dana Houser

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    Sup SS.

    That study did provide an argument in support of preferential shuttling of glucose into muscle cells vs fat cells.

    PS: In the mean while - what PPARy inhibitors/antagonists are even available?
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    antagonists: Berberine, Fucoxanthin

    Partial agonists: Salacia Reticulata

    off hand that is what i can remember strictly antagonizing the PPARy, There are definetly more, some tannins i believe from the banaba leaf.

    Possibly african mango and specific extracts of bitter melon.


    They are in numerous products. most GDAs will have one or another. Non stim fat burners SHOULD have one or another (or something that works similarly to supress adipogenesis but not by the PPARy pathway)

    This is why GDAs work with or without carbs. It still activated or attenuates specific receptors.
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    Good stuff. Thanks SS

    Back OT though as I am still looking for validation that these GDA's supposedly get shuttled into muscle vs fat (in a non-trained state)
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    ss your posts are always hella interesting!
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    The only thing I can think of isa PPARa agonist mixed with narangin. Narangin blocks glucose into adipose cell causing freed fatty acids and insulin resistance in adipose cells but not muscle cellsIts similar to a state called diabulimia (seen only in type one diabetics) except in nondiabetics muscle and liver still uptake. How safe it is long term, I'm not 100% sure
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    Now that would be HUGE if proven real world
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    I'd have to do the research. They did do it in vitro I believe on the 3T3-L1 cell line
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    Quote Originally Posted by ssbackwards View Post
    The only thing I can think of isa PPARa agonist mixed with narangin. Narangin blocks glucose into adipose cell causing freed fatty acids and insulin resistance in adipose cells but not muscle cellsIts similar to a state called diabulimia (seen only in type one diabetics) except in nondiabetics muscle and liver still uptake. How safe it is long term, I'm not 100% sure
    Check out cyclodextrin naringenin and the Harvard research done on it in humans.
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    Very cool. Here it is.....

    http://www.ncbi.nlm.nih.gov/pubmed/21494673

    http://www.sciencedaily.com/releases...0523101919.htm

    Someone needs to start selling this stuff

    Quote Originally Posted by ssbackwards View Post
    I'd have to do the research. They did do it in vitro I believe on the 3T3-L1 cell line
    Quote Originally Posted by Royd The Noyd View Post
    Check out cyclodextrin naringenin and the Harvard research done on it in humans.
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    Quote Originally Posted by Whacked View Post
    Very cool. Here it is.....

    http://www.ncbi.nlm.nih.gov/pubmed/21494673

    http://www.sciencedaily.com/releases...0523101919.htm

    Someone needs to start selling this stuff
    We do (ams) lol. But we matched it with a ph for some synergies. I've been looking into making it a solo product but haven't had a lot of time to work on it.
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    Royd which product??

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    I believe an ingredient in their DecaSARM is a nutrient partitioner.
    -Saving random peoples' nuts, one pair at at time... PCT info:
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    Quote Originally Posted by ManBeast View Post
    I believe an ingredient in their DecaSARM is a nutrient partitioner.
    Yep, it's cyclo'd naringenin.
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    Sweet man. Thanks. Def. gonna give it a try

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    Quote Originally Posted by ssbackwards
    The only thing I can think of isa PPARa agonist mixed with narangin. Narangin blocks glucose into adipose cell causing freed fatty acids and insulin resistance in adipose cells but not muscle cellsIts similar to a state called diabulimia (seen only in type one diabetics) except in nondiabetics muscle and liver still uptake. How safe it is long term, I'm not 100% sure
    Interesting!
    I will have to give these decaSARMs a try.
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    Was wondering what people here would think about this product. I read about 3.5 pages of this and noticed some of the ingredients in this GDA but some i did not recognize. I read everything on the website attached as i am brand new to GDA. Just trying to not get sold. Thanks ya'all love the site. mountaindogdiet. com/ultimateglucose. php
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