Prohormone - 5 on, 2 off

[sweetdaddy]

I vaguely remember years ago when prohormones were first introduced to the supplement market, a 5 days on, 2 day off dosing scheme was recommended. Does anyone still do this? I was considering it for my adrenosterone cycle simply because it would allow me to get 4 weeks out of the bottle instead of 3 if I skipped the weekends.

Does anyone have any thoughts about this type of dosing protocol?

 

[brittishbulldog]

never done any pulsing before why don't you just take it on days you train?

 

[AnonyMoose]

well - you know - i have never heard that even back then. as a matter a fact - it was my understanding the philosophy was to keep a steady stream of the ph's in your system by spreading the dosage times out evenly. since pulse cycling has been introduced - i would be more inclined to take that route - and it might spread that bottle out farther for you.

 

[jtbull]

I think i read a few places abotu using the ECA stack or clen like that, but dont recall that protocal for prohormones.

 

[Mathb33]

I wouldn’t recommend it... what PH we talking about??

 

[Darkhorse192]

what was the logic behind this? extend the cycle?

 

[Mathb33]

Pretty sure the logic back then was to avoid sides or diminish it

 

[delsolrob]

When there was still major concerns about liver damage with some of the new compounds on the market (think Methyl 1T) and people were concerned with toxicity, pulsing was conceptualized to minimize the stress on the body.

There were also discussions about minimizing shutdown, but I don't think that was ever proven to be beneficial for that.

At this point, with TUDCA and other supports, and less toxic compounds available, I don't think there's really any benefit to pulsing...we also have a better understanding on toxicity

 

[Aleksandar37]

Pretty sure the logic back then was to avoid sides or diminish it

And to avoid running PCT. This was popular with epistane, but I thought it was only like 3-4 times a week for the "pulse" cycle.

 

[Old Witch]

And to avoid running PCT. This was popular with epistane, but I thought it was only like 3-4 times a week for the "pulse" cycle.

Nowadays the pulse I see guys using to avoid pct is pre training and precomp doses, generally powerlifters, as it happens to be.

I’ve seen and heard tell of people using steroids such as anavar or winstrol 5 on 2 off though that could be pre training as well as bodybuilders do or did often train 5 days a week.

 

[Aleksandar37]

Nowadays the pulse I see guys using to avoid pct is pre training and precomp doses, generally powerlifters, as it happens to be.

I’ve seen and heard tell of people using steroids such as anavar or winstrol 5 on 2 off though that could be pre training as well as bodybuilders do or did often train 5 days a week.

Is it based on anything scientific or are people just guessing and going with how they "feel."

 

[Aleksandar37]

Nowadays the pulse I see guys using to avoid pct is pre training and precomp doses, generally powerlifters, as it happens to be.

I’ve seen and heard tell of people using steroids such as anavar or winstrol 5 on 2 off though that could be pre training as well as bodybuilders do or did often train 5 days a week.

Is it based on anything scientific or are people just guessing and going with how they "feel."

 

[Old Witch]

Generally the consensus is with the 5 on 2 off dosage of orals you’re just giving the liver a weekly break, which is medically sound and supported as effective.

Powerlifters are still convinced though that if they’re just taking stuff for a week at a time, or three days a week, that they aren’t getting shut down. And they probably aren’t, not to a noticeable degree.

It does take time for shutdown to occur, the compounds are not outright toxic to the testes and brain.

 

[Wobmarvel]

The problem with this is surely you must reduce effects of the prohormone itself. A lot of orals take weeks to kick in and build up in your system. By stopping and starting like that would you not be prolonging this or preventing effectiveness altogether.

 

[Old Witch]

The problem with this is surely you must reduce effects of the prohormone itself. A lot of orals take weeks to kick in and build up in your system. By stopping and starting like that would you not be prolonging this or preventing effectiveness altogether.

Exactly. Only a certain number of compounds work well in this dosage. Anavar, dianabol, anadrol, methyl tren, halotestin, M1T, superdrol... notice a pattern?

 

[Rostam]

Is it based on anything scientific or are people just guessing and going with how they "feel."

From what I see in other thread on this topic it seems this method is derived from corticosteroid pulsing techniques used in kids.

Here is one of the thread.

https://anabolicminds.com/forum/steroids/62121-how-pulse-orals.html


There are few threads on the topic here. check posts by Dr.D. I think he was the one talking about it some 10-15 years ago.

 

[Old Witch]

From what I see in other thread on this topic it seems this method is derived from corticosteroid pulsing techniques used in kids.

Here is one of the thread.

https://anabolicminds.com/forum/steroids/62121-how-pulse-orals.html


There are few threads on the topic here. check posts by Dr.D. I think he was the one talking about it some 10-15 years ago.

People used to do it in the 70s and 80s with the methylated steroids per many doctors recommendations. That was how I learned of it, from an old guy back when I first started.

Gotta love old guys. They actually do things.

 

[PoSiTiVeFLoW]

Gotta say for someone who did monthly bloodwork and ran a lot of oral methylated compounds like DMZ, M1T, etc.. 5 on 2 off makes no sense for hepatoxicity reduction, even with TUDCA and NAC and hydrating well.

Takes at least 4-6 weeks or more for my ALT/ AST liver values to get back to normal, even with cycle support. If you run a number of cycles close together to rehab the liver will take longer.

5 on / 2 off sounds like a theory for those who wish to stay on cycle and not feel guilty about damaging themselves?