x_muscle
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ok guys. im cell biology student, and because i like body building i read alot about growth factors and other factors that effect the muscle cell growth. in my search i found something intresting about (TNF-alpha) growth factor, which effect the muscle directly.
for people who dont know what TNF-alpha (tumor necrosis factor alpha) is. Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness of muscle. TNF-α has long been associated with muscle pathology and was originally designated 'cachectin' in recognition of its catabolic action. TNF-α may stimulate catabolism in muscle and protein loss in muscle. you can read more here:
http://www.pubmedcentral.nih.gov/ar...cgi?artid=59514
so from the information above you see that TNF-alpha is bad thing for bodybuilders because its responsible for catabolsim and muscle loss. so that evoked my intrest to find a way to block this growth factor, to reduce muscle catabolisim. in my search i found a drug called infliximab an anti- Inflammatory used to treat Crohn's disease. this drug inhibit the ammune system ability to produce TNF-alpha.
in theory bloacking TNF-alpha will come to bodybuilder advantage, because it will stop muscle wasting when dieting.
this drug appeared to have also a unique propety as if its comparable to Growth hormone in its effects. according to: http://216.239.53.104/search?q=cach...le+growth&hl=en "Growth hormone appeared almost as effective as the anti-inflammatory drug infliximab, the only medication approved specifically for Crohn's disease. Slonim's study, however, did not perform exams to see whether the intestinal tissue was healthier."
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this dug is only avilable for IM injection, i like to disscuse this theory wth you guy to see how usefull this compund could be for bodybuilders!
for people who dont know what TNF-alpha (tumor necrosis factor alpha) is. Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness of muscle. TNF-α has long been associated with muscle pathology and was originally designated 'cachectin' in recognition of its catabolic action. TNF-α may stimulate catabolism in muscle and protein loss in muscle. you can read more here:
http://www.pubmedcentral.nih.gov/ar...cgi?artid=59514
so from the information above you see that TNF-alpha is bad thing for bodybuilders because its responsible for catabolsim and muscle loss. so that evoked my intrest to find a way to block this growth factor, to reduce muscle catabolisim. in my search i found a drug called infliximab an anti- Inflammatory used to treat Crohn's disease. this drug inhibit the ammune system ability to produce TNF-alpha.
in theory bloacking TNF-alpha will come to bodybuilder advantage, because it will stop muscle wasting when dieting.
this drug appeared to have also a unique propety as if its comparable to Growth hormone in its effects. according to: http://216.239.53.104/search?q=cach...le+growth&hl=en "Growth hormone appeared almost as effective as the anti-inflammatory drug infliximab, the only medication approved specifically for Crohn's disease. Slonim's study, however, did not perform exams to see whether the intestinal tissue was healthier."
---------------------------------------------------------------------------------
this dug is only avilable for IM injection, i like to disscuse this theory wth you guy to see how usefull this compund could be for bodybuilders!
