Putative pheromone activates cortical fields in the human brain..

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The putative pheromone androstadienone activates cortical fields in the human brain related to social cognition.

Gulyas B, Keri S, O'Sullivan BT, Decety J, Roland PE.

Department of Neuroscience, Karolinska Institute, S-171 77 Stockholm, Sweden. [email protected]

Abstract:
Using 15O-butanol positron emission tomography (PET), we measured regional cerebral blood flow changes in five healthy young women during exposure to androstadienone, a putative human pheromone, as well as pleasant (gamma-methyl-ionone), unpleasant (methyl-thio-butanoate), and neutral (dipropylene glycol; vehicle compound) odours. Compared with the odorous substances, androstadienone activated a widely distributed neuronal network. Two large cortical fields exhibited consistent activation in each contrast: the anterior part of the inferior lateral prefrontal cortex (PFC) and the posterior part of the superior temporal cortex (STP). Intriguingly, these areas were deactivated by gamma-methyl-ionone and methyl-thio-butanoate. These brain regions can be identified as cortical fields underlying other than olfactory functions, including various aspects of social cognition and attention.
Summary: pheromones stimulate female brains ;)

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