nattydisaster
PESCIENCE.com
- Awards
- 3
The Breakthrough Thermogenic
A long awaited release...PES is proud to announce its first ever stimulant based capsuled thermogenic.
Norcodrene delivers an all new feel focused around energy, mood, and thermogensis.
Norcodrene is a carefully formulated blend of ingredients from every angle. While each ingredient serves its own purpose in the formula, each ingredient works in tandem with one or more other ingredients in the blend to further enhance specific pathways in the body.
As the makers of Alphamine, the industry's first true powdered thermogenic, we knew we had to deliver a product that really compares to nothing else available today. Our solution is Norcodrene.
Not Just A Caffeine Pill...
Today, most products in the diet category like to talk about one thing...ENERGY. One after another saying they are the next most energizing diet product...
As a result, products are now turning to more and more caffeine...and less ingredients that actually have fat burning abilities (in some cases...products with zero fat burning capable ingredients!).
Don't judge diet products on how much energy they give you...all you are doing is comparing who put the most caffeine in the capsule. Judge the product over the course of 4-8 weeks along with your diet and training...how were your results?
NEWS FLASH...How energetic a pill makes you doesn't correlate to fat loss. If it did, we could all just drink coffee a few times per day and be at 5% body fat like it was no big deal.
Perfected Formula
With multiple synergistic stimulants in each capsule, the feel Norcodrene delivers will have you soon realizing it stands apart from everything else in this category. Is it energizing? Of course...it also gives a remarkable mood boost too. But it isn't "just an energy pill" like so many other products you will stumble upon. It is a carefully formulated final product that is comparable to nothing else out there.
Norcodrene contains our trademarked unique extract, SA2-A2, a special Boldine extract. An ingredient brand new to the industry, developed especially for Europe. Many know that finding an effective Alpha-2 Adrenergic Antagonist in Europe is impossible – until now! No more yohimbine needed.
Boldine is a novel alpha-2 adrenergic receptor antagonist that, unlike its widely marketed counterparts (e.g. Yohimbine), does not possess attributes that predispose users to anxiety or unpleasant stimulation [1][2][3].
The alpha-2-adrenergic receptor is found throughout the body and functions chiefly to limit the amount of norepinephrine that is released at the site of the receptor. In fat cells, norepinephrine is a powerful signaling molecule that, along with epinephrine, initiates a cascade of reactions that result in fat loss.
Therefore, when the alpha-2 receptor is functional, norepinephrine release is reduced and fat loss gets halted. Regional fat, otherwise known as the “stubborn fat” that just doesn’t go despite how hard you try, may be due to local variations in alpha-2 receptor density[4].
Boldine, a natural alkaloid which deactivates/antagonizes the alpha-2 receptor, can allow fat loss to proceed undisturbed. This may again be of particular importance when attempting to lose fat in stubborn areas like the midsection, love handles, and thighs.
Unlike the well-known alpha-2 antagonist Yohimbine, Boldine does not possess the profound anti-serotonergic activity that gives yohimbine users anxiety [1][2][3], and furthermore, rather than vasoconstricting and increasing blood pressure, Boldine actually vasodilates [5].
Also unlike yohimbine, boldine possesses fat loss benefits that are independent of its alpha-2 antagonistic effects. Boldine has the unique ability to induce adiponectin release from fat cells [6].
For maximal benefits and feel, take your servings on an empty stomach and do not eat for at least 45 minutes afterwards.
Enjoy the innovation.
References
1. De Las Heras, B., et al. "A Study of the Adrenergic Activity of the Alkaloids Boldine and Glaucine." Pharmazie 45.6 (1990): 443-44. Web.
2. Eltze, M., et al. "Affinity Profile at Alpha(1)- and Alpha(2)-adrenoceptor Subtypes and in Vitro Cardiovascular Actions of (+)-boldine." Eur J Pharmacol 443.1-3 (2002): 151-68. Web.
3. Chulia, S., et al. "The Effect of S-(+)-boldine on the Alpha 1-adrenoceptor of the Guinea-pig Aorta." Br J Pharmacol 119.7 (1996): 1305-312. Web.
4. Arner, P. "Adrenergic Receptor Function in Fat Cells." Am J Clin Nutr. 55.1 (1992): 228S-36S. Web.
5. Chen, Keh-Shaw, Feng-Nien Ko, Che-Ming Teng, and Yang-Chang Wu. "Antiplatelet and Vasorelaxing Actions of Some Aporphinoids." Planta Medica 62.02 (1996): 133-36. Web.
6. Yu, Bangning, Carla Cook, and Nalini Santanam. "The Aporphine Alkaloid Boldine Induces Adiponectin Expression and Regulation in 3T3-L1 Cells."Journal of Medicinal Food 12.5 (2009): 1074-083. Web.
