i been reading in Dr. Shippen's book and he recommends more of a vegetarian diet and taking in Soy Protein, is this best for keep T levels up and estrogen down?
Look at the date the book was writen (and hopefully in correct direction).i been reading in Dr. Shippen's book and he recommends more of a vegetarian diet and taking in Soy Protein, is this best for keep T levels up and estrogen down?
I'm preparing some questions for my freind to ask the man him self and this is going to be one of them ..Dr. Shippen has changed his mind about several things in his book. I've similarly reversed myself along the way. This is a rapidly evolving field.
this applies to males as well. Aromatase does the trick for us. The brain doesn't need much estrogen but it does need some. One author, please don't ask the source, as I cannot recall, speculated that the incidence of old age dementias is lower in males is due to our higher levels of testosterone and hence more estrogen in the brain--this certainly applies to Alzheimers. I raised this point with the folks at the Johns Hopkins' Alzheimers Center and this was the response I got. So relative to estrogen, as males we need some----certainly for our bones, and certainly for our brains.I'm preparing some questions for my freind to ask the man him self and this is going to be one of them ..
Would soy lechtithan granules fall into this catagory as well because I am looking to increase my source of choline which this is a viable source for sure for cell membrane structure. I know choline does flush out ones liver very well. and my RBC testing should I was low, but also estrogen imbalances can cause alteration in choline absorption as well
Estrogens have been shown to be important for the differentiation of certain nuclei of the brain (Gorski et al., 1980), and recent evidence suggests that estrogens may be important for normal brain function throughout life (Simpkins et al., 1994). In adult rats, estradiol (E2) has been shown to enhance sprouting of commissural association fibers in the hippocampal dentate gyrus after entorhinal cortex lesions (Morse et al., 1986). Estrogen environment influences the synaptology of the hippocampus, because changes in synaptic density in the CA1 region are associated with endogenous (Wooley and McEwen, 1992) and exogenous (Wooley et al., 1990) levels of 17-estradiol (17-E2). Recently, we have shown that 17-E2 induced the expression of the neurotrophic factors, nerve growth factor, and brain-derived neurotrophic factor (Singh et al., 1993, 1995). We and others have observed an increase in the high affinity uptake of choline (O'Malley et al., 1987; Singh et al., 1994), in the levels of choline acetyltransferase (Luine et al., 1975, 1980; Singh et al., 1994), and in the performance of memory-related behavioral tasks (Singh et al., 1994) after estrogen treatment of ovariectomized rats. Collectively, these results indicate that estrogens are important in the maintenance of normal neuronal function related to cognition, an observation consistent with the studies of Sherwin et al. (Sherwin, 1988; Phillips and Sherwin, 1992) showing steroid modulation of memory and cognition in women subjected to surgical menopause.
17alpha -Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells -- Green et al. 17 (2): 511 -- Journal of Neuroscience
Now the question is does this apply to also male as well?
i know e2 can interfer with methylation of the body and also this can acuse choline defieincy as well..
I am not sure. I am agreeing that TRT is neuroprotective. However, optimal TRT is a balance of hormones. Rather than speculate on mechanism I am not sure of, I wish Marianco was here to elaborate. If AI's work in the brain, then hormones and their inhibitors are there also. The thread is about soy, estrogen, and the brain. When I started HRT a few year ago, the doctor who was looking at my bloodwork and my wife's looked up at the both of us and annouced that I had more estrogen floating around than my wife. For an older guy like myself this situation would have long term deleterious effects on my brain, my heart, etc. And yes, there would also be negative psychological effects--depression, anxiety, poor focus and attention, etc.I'd ask this author how then it can be TRT has shown such neuroprotective protective effects.
It looks like the estrogen thatis so good for our brains is made witin the brain itself--not riding in on the blood. That is why e must be so careful not to lower E too much, as AI's work in the brain parenchyma as well, I prefer competitive inhibitors over suicide inhibitors, and no long term SERM use.
Thoughts, HeadDoc?
What is the optimal testosterone and estrogen range?The key take home point here is that estrogens, like all hormones, need be in the optimimal range.
That sucks about the almonds.the only liquids i would consum is fresh vegetable juice or water
Almond ''Pasteurization'' May be Worse Than Previously Thought
about Flax seeds
http://www.mercola.com/2004/jul/21/flax_seed_oil.htm
AWESOME post. Thank you!
That sucks about the almonds.
But as far as the flax seeds go, I really can't trust anything from a website that requires me to type in my email address before I can read it.
In the past, I've read some sites (from questionable websites) that say flax seeds increase the risk of prostate cancer, but I've also read many more studies on pubmed that say the complete opposite.
And pubmed never requires me to type in an email address before reading their studies.
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