BRITE™ in stock!
- 08-30-2018, 12:44 PM
BRITE™ in stock!
I made some minor adjustments to the formula, slightly reducing the Korean Pine Nut Oil and Peppermint, while increasing the key ingredient - the bitter melon seed oil.
The flavor is MUCH improved!
In stock and shipping now, and the 15% off discount code running until next week.Evolutionary Muse - Inspire to Evolve
Flawless Skin Couture - We give you the tools to make you Flawless
- 08-30-2018, 02:32 PM
08-30-2018, 02:44 PM
08-30-2018, 06:03 PM
08-30-2018, 07:15 PM
08-30-2018, 07:16 PM
08-30-2018, 07:18 PM
09-01-2018, 11:54 AM
09-07-2018, 05:03 PM
I've been reading a lot about BRITE, and its ingredients, and I'm super intrigued. It really sounds like a winner. However, with all of this PPAR activation and de-activation, I wonder if it's really the safest thing to use long term, which long term usage being where this product is really supposed to shine.
From my understanding, which may be incorrect, increasing PPAR alpha activation in one tissue may be good, whereas increasing it in another may be bad. Increasing PPAR-alpha and PPAR-gamma at the same time increases bladder cancer risk, but no risk is associated with increasing one but not the other.
Decreasing PPAR-gamma activation (an action of BRITE) may help improve fat loss, yet increased PPAR-gamma activation is said to be correlated with cancer cell apoptis in many tissues and organs, such as brain, colon, lung, pancreas, liver, etc..
PPAR-delta activation is obviously great for muscle endurance and fatty acids oxidation, yet there are possibly correlations between increased activation of this gene and increases in lung, colon, and liver cancers (liver studies show both positive and negative correlation).
So, basically, obviously these pathways are all unbelievably complicated. And we can see that either being an agonist or antagonist of a specific PPAR gene can be both good, or bad, depending on what you're trying to do. Are the main PPAR activators and suppressors in BRITE, BMSO & KPNO, tissue specific by any chance? As in, BMSO being a PPAR-alpha agonist in fat cells, but not in the bladder, for example? Or, does the fact that these fatty acid ligands are NOT high-affinity selective receptor agonists greatly reduce any of this concern?
The studies on BMSO, Perilla, and KPNO are all very promising, and have me SUPER interested in running BRITE for say like 3 months, but all this PPAR alpha/delta activation coupled with gamma deactivation has me a little weary.
Any thoughts to ease mine, or possibly anyone else, concerns?
09-08-2018, 01:59 PM
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