As mentioned before you need to look at underlying pathologies. Just recently, I found 2 guys with hidden iron overload with low testosterone. After reviewing labs and genetics having doctors dig deeper with recommended testing it was confirmed. Now we are working to lower the ferritin stores down to 20-50 with blood donating and other modalities. Not only did this potentially save them from having to go one TRT, but also potentially their lives. Again one needs needs to look at total picture and not just focus on hormones. Btw all CBC, ferritin levels were normal, but had elevated iron saturation of >55. Ferritin is not a true indicators of iron metabolism only the stores and still upon the new research coming out ferritin levels should be as low as they can go as long as it does not effect the RBC and other iron indices. We truly need to take a step back to looks what factors such as emotional environmental, biochemically, and genetically are not being addressed. TRT will mask iron overload as I just found out my self for 15 years. Just because you are a carrier of the gene or heterozygous that still means it can express. When you doctors tells you, other wise, they are full of SH!T and do not understand how epigenetics work. Mark my word as I have mentioned this stuff 10 years ago, going to specialist often addresses symptoms not the root cause. TRT and thyroid medication in young people is not necessary over prescribe, due to doctors practicing “lazy medicine”. Thyroid is the most over prescribe medicine we see in “functional medicine” model sadly..