Safety of cycles

deaconbill

Member
How safe is a cycle of T-1 Pro?  Do any of you know of any longterm side effects from a transdermal cycle?  Heard any horror stories?  Any body stats that one should be monitoring while on a cycle?  Any info would be appreciated.  Thanks!
 
Surely someone has something to say or is this one of those "I'm not going to touch that one" posts?  It may be nothing but I was having some doubts and needed some feedback.  I am two wks into this cycle and am seeing good gains, just need encouragement.  Thanks!
 
No PH's are safe.

Dont overdo it and you should be fine. 4-ad has very little side effects. 1-test is the one that gives you really good gains, but side effects arise from DHT formation (Hair baldness, acne)

I mean a moderate dosage of 150mg/day should creat no problems. DO remember, there will be some temporary side effects such as lethargy and loss of libido.
Hair loss is not temporary unfortunately.

If you want to go total safe route --- 19nordiol and boldione is a good choice. 1-test is not too bad either.... stay away from --dione products such as andro etc.

read Big Cat's article, its very informative, or grab a Biochem book if you want more detailed info on exact pathways etc. even big cat;s artice is written from a bodybuilder's perspective, so it may not be completely unbiased, you can grab some independent studies from medical journals etc.
Pubmed is a good start... Link Removed (or do a search for Pubmed)
 
Originally posted by deaconbill
How safe is a cycle of T-1 Pro?  Do any of you know of any longterm side effects from a transdermal cycle?  Heard any horror stories?  Any body stats that one should be monitoring while on a cycle?  Any info would be appreciated.  Thanks!
Click to expand...
 

I think this is a sensitive subject or taboo and perhaps if we do not talk about it will not happen, wrong! It is good to talk about it.

Potential side prohormes and prosteroids side efects: Note the word Potential. What you need to know before you go for it.

Increased risk of prostate enlargement and cancer, decreased testicular size,Gynecostomia (bitch tits), acne, baldness, Insomnia, infertility, aching joints, muscle cramps, water retention, mental addiction, increased risk of psychosis, decrease/increased sex drive, increased risk of aggression, nose bleeds, risk of muscle tears, decreased in inmune response, increased of tendon injuries, increased of mood disturbances, increased risk of cardiovascular disease, risk liver and kidney cancer. " Some side effect are irreverisble, even with short term use" (Shugarman,2002). and yes he mention the transdermals, t-1, and andros, what a boomer.

Scary, but it is real, the above are manageable risk,  if you do your home work should be okay, I rather manage the above, that the ones of being fat can give you.  

Ref: Natural Muscle Magazine, October issue 2002, article by Alan E. Shugarman, M.S., R.D.
 
Thanks Rhino.  I had had achy elbow joints just since starting my cycle and had wondered if the cycle was responsible.  It isn't so bad that I stopped my cycle, though.  Thanks again.
 
Originally posted by deaconbill
Thanks Rhino.  I had had achy elbow joints just since starting my cycle and had wondered if the cycle was responsible.  It isn't so bad that I stopped my cycle, though.  Thanks again.
Click to expand...

 

No problem, here to help.
 
Got this off of the Avant Labs forum

Got this off of the avant labs forum

 

<SPAN class=postcolor>FACT 1! A group of bodybuilders who used steroids were compared to bodybuilders who had never used steroids. The men's hearts were examined using echocardiography, (a type of sonar picture that allows doctors to see the heart without having to use any invasive procedures). They found that during steroid cycles the users had left ventricles (the main pumping chamber of the heart) that were 25% greater in mass than the non-users! This increas in mass caused the walls of the steroid user's heart muscle to be almost 20% thicker while on steroids! Although the heart was bigger during active steroid use, the cardiovascular fitness of these individuals was nearly 18% less than non-users. When the steroid users were off the steroids, their heart size decreased, but never fully returned to its normal size!(1,2) Now, if some of you think that it was just a "coincidence" and nothing more, read very carefully the second fact.

FACT 2! A study published in the journal "Cardiology" (1997;88:50-51), offered a unique perspective of the effects of long term anabolic steroid usage and heart function. The study was unique because it involved fraternal twin bodybuilders, one of whom has used steroids for 15 years, while the other was drug free. Both of these men had trained for over 20 years. They were described in the study as "extremely large with profound muscular hypertrophy". They had won several state and national titles in bodybuilding and powerlifting. The twins had bodyfat levels below 10 percent, and followed the same diet and training regime on a yearly basis. The primary test to access their cardiac function was echocardiography. (As I previously said, it's a machine that uses reflected ultra sonic waves to show the structure and function of the heart.)

Both men showed normal blood pressure readings. The drug-free twin showed a testosterone level of 6.2 nanongrams per mililiter of blood, and the steroid twin had a higher than normal level of 11.5 ng/ml! (The normal range for testosterone is 2.8-8.8, and as you can easily understand, the steroid twin had testosterone levels almost 3 times the high normal level) The echocardiography tests showed that both men, with similar genetic backrounds and the same training and diet regimes, showed little difference in gross heart function. However, the steroid user showed a LARGER left ventricular wall size with a decreased ventricular compliance. (That means that the pumping chamber of his heart was LARGER than his brother's, while also being a bit stiffer!)

The heart stiffness that occurs in steroid-using bodybuilders is thought to be brought on by an increased sensitivity of heart muscle to catacholamines, such as epinephrine, induced by steroids. And guess what friends, this scenario may have played a role in the sudden deaths due to heart failure that have occured in a small percentage of regular steroid users.


Arnold had to have heart surgery anybody remeber why? </SPAN>
 
Re: Got this off of the Avant Labs forum

I think he had  failing tube in area in the heart needed repair if not he would had died, I saw the interview on TV, Explain about it but definely they went around the real reason for the problem.  Also Jesse Ventura had something similar. Went to surgey also.
 
Interested in more information? - this one is from PUB MED

Left ventricular wall thickening does occur in elite power athletes with or without anabolic steroid Use.

Dickerman RD, Schaller F, McConathy WJ.

Department of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Tex., USA.

Reports on the occurrence of left ventricular wall thickening in resistance-trained athletes have rejected the possibility for this physiological adaptation to occur without concomitant anabolic steroid abuse. Others have concluded short bursts of arterial hypertension that occur with maximal weight lifting are not sufficient to induce left ventricular wall thickening, and left ventricular wall thickness >/=13 mm should not be found in pure resistance-trained athletes. Therefore, we examined 4 elite resistance-trained athletes by two-dimensional echocardiography. In addition, we retrospectively examined the individual left ventricular dimensions of 13 bodybuilders from our previous echocardiographic studies. All 4 elite resistance-trained athletes had left ventricular wall thicknesses beyond 13 mm. One of the elite bodybuilders has the largest left ventricular wall thickness (16 mm) ever reported in a power athlete. Retrospectively, 43% of the drug-free bodybuilders and 100% of the steroid users had left ventricular wall thickness beyond the normal range of 11 mm. In addition, 1 drug-free subject and 3 steroid users were beyond the critical mark of 13 mm. No subjects demonstrated diastolic dysfunction. In contrast to previous reports, we have demonstrated that left ventricular wall thicknesses >/=13 mm can be found routinely in elite resistance-trained athletes. The use of anabolic steroids concomitant with intensive resistance exercise does appear to augment left ventricular size without dysfunction. Anabolic steroids may accelerate left ventricular wall thickening indirectly by increasing strength, thus augmenting the pressor response.

PMID: 9778553 [PubMed - indexed for MEDLINE]

We need more discussion about cardiomegaly as a consequence of anabolic steroids - what are the practical and realistic dangers. This needs to be discussed in a non biased way - free from pontificators that are warning us against all things considered against societies norms. For example - in the 19th century - masturbation was considered dangerous to unborn generations and could adverse health effects. We need to be reasonable and realistic in our concerns.
 
Wow!  Now I am immpressed with the posts.  I am not planning on quitting my cycle or anything like that, I just wanted to be aware of the info and sturies that have been done.  Interested in hearing more.  Thanks again.
 
Testosterone as Male Contraceptive

Another Interesting Article from Yahoo Health

"Hormone Therapy a Potential Male Contraceptive
December 05, 2002 02:31:47 PM PST, Reuters

An experimental hormone combination holds promise as a male contraceptive, the results of a new study suggest.
The combination, which includes a new formulation of the hormone testosterone, effectively suppressed sperm in all men in the small study. However, the study was stopped when some men experienced increases in liver enzymes, although the role of the hormone therapy in this increase is unclear.

Developing an effective and convenient male contraceptive has been difficult, in part because of the rapid rate at which men produce sperm. During a single month, when a woman's ovaries produce a single egg, a man produces millions of sperm.

Though testosterone is often linked with virility, treatment with the hormone actually suppresses the production of sperm, a process called spermatogenesis, by reducing levels of hormones called gonadotropins.

Unfortunately, too much testosterone can have harmful effects, such as reducing levels of HDL, the "good" form of cholesterol. To block this and other side effects, experimental male contraceptives often include another type of hormone, frequently a type used in female contraceptives.

In the new study, Dr. R. A. Anderson, of the MRC Human Reproductive Sciences Unit in Edinburgh, Scotland, and colleagues tested a combination that included a new formulation of testosterone designed to be longer-lasting than other forms of the hormone. Long-lasting testosterone would be beneficial not only in a male contraceptive, but also for the treatment of men with low testosterone levels.

In the study, 20 healthy Chinese men injected testosterone once every 4 weeks. At the start of the study, the men received implants containing the hormone etonogestrel, which mimics the effects of progesterone. The Netherlands-based drug company NV Organon provided the hormones.

By 12 weeks, all of the men experienced a substantial drop in sperm production. At that time, 80% of the men had achieved azoospermia, which is a complete lack of sperm in the semen, the researchers report in a recent issue of the journal Contraception.

Although the study was designed to last a year, Anderson and his colleagues soon halted the study when they observed that liver enzymes had risen in about half of the men--although all appeared healthy. The researchers are not sure what caused the increase, because in a separate group of men from the same region who were not taking the experimental contraceptive, about one third also had elevated liver enzymes.

Some men taking the contraceptive experienced several other changes, including weight gain and increases in blood pressure, oxygen-carrying molecules called hemoglobin, total blood volume and a type of LDL cholesterol. Also, in some men, testosterone levels increased to extremely high levels.

Although the researchers suggest that liver function should be followed carefully in future studies of the combination, they conclude that this formulation of testosterone offers several advantages over other forms of injectable testosterone that are currently available.

They call for further research of the product as both a treatment for testosterone deficiency and a possible male contraceptive.

SOURCE: Contraception 2002;66:357-364."

:saw:
 
Deaconbill, sorry no science or articles. When I notice a side effect that gets too uncomfortable for me, that is when I stop. So far that has worked well for me. Maybe I would have experienced more gains (if I would have pushed it), but to date I have had no long term side effects. Best of luck. Just my 2 cents.
 
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